STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
azo2999Conserved hypothetical secreted protein. Homology to NE2572 of N.europaea of 46% (tremble:Q82RZ3). Has PF05951, Bacterial protein of unknown function (DUF882);IPR010275; This family consists of a series of hypothetical bacterial proteins of unknown function. Signal Peptide Present. No TMH present; Conserved hypothetical protein. (193 aa)    
Predicted Functional Partners:
ycbB
Putative periplasmic protein [ycbB], 39% identity(57% similarity) to TrEMBL;Q82RZ2.Q9A853(30% identity) Signal Peptide Present. Has PF01471, Putative peptidoglycan binding domain; IPR002477 PG_binding; This domain, peptidoglycan binding domain 1, may have a general peptidoglycan binding function. It is composed of three helices and is found at the N or C terminus of a variety of enzymes involved in bacterial cell wall degradation. * Muramoyl-pentapeptide carboxypeptidase (EC:3.4.17.8) * N-acetylmuramoyl-L-alanine amidase cwlA precursor (cell wall) hydrolase, autolysin, EC:3.5.1.28) * A [...]
 
     0.928
azo0398
Putative beta lactamase; Probable Hypothetical protein ycbL. TREMBL:Q8Y2S7-43% identity,57% similarity. TIGRFAM:2A0115-Benzoate transport proteins belong to this group. Benzyl alcohol,benzaldehyde, benzoate, and anthranilate are metabolized via catechol, cis,cis-muconate, and the beta-ketoadipate pathway in some bacteria InterPro: Metallo-beta-lactamase superfamily Pfam:Metallo Beta lactamase superfamily, Phage lysozyme TMHMM predicted transmembrane heleces ftsZ: cell division protein FtsZ; Function unclear.
  
    0.556
ycbL
Hypothetical protein ycbL. TREMBL:Q7P1X5-63% identity. Interpro:IPR001279-Blactamase like Pfam-GlyoxylaseII family relationship. Phosphoribosylglycinamide synthetase,Respiratory chain NADH dehydrogenase; KH domain and RTX toxin acyltransferase family relationship. ispD: 4-diphosphocytidyl-2C-methyl-D-ery; High confidence in function and specificity.
  
    0.556
azo3001
Conserved hypothetical membrane protein. Homology to XAC149 of X. axonopodis of 41% (trembl|Q8PLP4(SRS)). Pfam: DedA family. This family combines the DedA related proteins and YIAN/YGIK family. Members of this family are not functionally characterised. These proteins contain multiple predicted transmembrane regions. no signal peptide. 4 TMHs; Conserved hypothetical protein.
       0.520
azo0296
InterPro:IPR001279- Metallo-beta-lactamase superfamily,glyoxalase II family, that catalyse the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid. TREMBL:Q7WEK1-55% Identity. Pfam-Presence of phosphoribosyltransferase, tissue factor, and GMP reductaseC like domains Signal P predicting signal peptide and TMHMM predicting transmembrane helices. ccoP: cytochrome c oxidase cbb3-type s; High confidence in function and specificity.
  
    0.425
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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