Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
soxBSarcosine oxidase, subunit beta counts to the FAD dependent oxidoreductases. Similar to trembl|Q82M71 (29%) and to trembl|Q9V0K7 (26%). Pfam (PF01266): D-amino acid oxidase ProSite (PS50205): NAD binding site ProSite (PS50204): UBA/THIF-type NAD/FAD binding fold; Specificity unclear. (394 aa)    
Predicted Functional Partners:
gcvT
Glycine cleavage T proteins are part of the glycine cleavage multienzyme complex (GCV) found in bacteria and the mitochondria of eukaryotes. The T-protein is an aminomethyl transferase that catalyses the following reaction: (6S)-tetrahydrofolate + S-aminomethyldihydrolipoylprotein = (6R)-5,10-methylenetetrahydrofolate + NH3 + dihydrolipoylprotein Similar to sprot|GCST_NITEU (60%). Pfam: Glycine cleavage T-protein (aminomethyltransferase) TIGRfam (TIGR00528): Glycine cleavage T-protein (aminomethyl transferase); High confidence in function and specificity.
 
 0.971
gltB
Ferredoxin-dependent glutamate synthase,; Specificity unclear.
    
 0.879
ooxA
Putative opine oxidase subunit A. Homology to ooxA of A. tumefaciens of 37% (sprot|OOXA_AGRT4). OXIDATIVE CLEAVAGE OF OCTOPINE INTO L-ARGININE AND PYRUVATE (BY SIMILARITY). InterPro: FAD-dependent pyridine nucleotide-disulphide oxidoreductase (IPR001327), NAD-bining site (IPR000205) Pfam: Pyridine nucleotide-disulphide oxidoreductase no signal peptide no TMHs; Family membership.
 
 0.828
soxF
Probable sulfide dehydrogenase, falvoprotein subunit (Flavocytochrome C flavoprotein subunit). Homology to fccB of C. vinosum of 40% (sprot|DHSU_CHRVI). Pfam: Pyridine nucleotide-disulphide oxidoreductase signal peptide no TMHs; Family membership.
 
 
 0.816
gcvP
Glycine cleavage system P-protein; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.
   
 
 0.792
etfB4
Probable electron transfer flavoprotein, beta subunit. Homology to etfB of B. japonicum of 54% (sprot|ETFB_BRAJA). The electron transfer flavoprotein serves as a specific electron acceptor for some dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase)(By similarity). InterPro: Electron transfer flavoprotein beta-subunit (IPR000049) Pfam: Electron transfer flavoprotein beta subunit no signal peptide no TMHS; High confidence in function and specificity.
  
 
  0.684
etfA4
Probable electron transfer flavoprotein, alpha subunit. Homology to etfA of B. japonicum of 49% (sprot|ETFA_BRAJA) The electron transfer flavoprotein serves as a specific electron acceptor for some dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase)(By similarity). InterPro: Electron transfer flavoprotein alpha-subunit (IPR001308) Pfam: Electron transfer flavoprotein alpha subunit no signal peptide no TMHs; High confidence in function and specificity.
    
  0.654
azo3003
Conserved hypothetical transcriptional regulator,LysR family. Similar to SWISSPROT: sprot|NTCB_SYNP7 (18% Synechococcus sp. (strain PCC 7942) (Anacystis nidulans R2), nitrogen assimilation transcriptional activator NtcB) Pfam: PF00126 Bacterial regulatory helix-turn-helix protein, lysR family. HTH reporting nucleic acid binding motif; Family membership.
 
     0.641
azo3007
Conserved hypothetical protein. Homology to BB1278 of B.bronchiseptica of 35% (trembl:Q7WMW2). Has PF05962,Bacterial protein of unknown function (DUF886);IPR010282; This family consists of several hypothetical bacterial proteins of unknown function. No signal peptide or TMH present.
 
     0.629
etf2
Probable electron transfer flavoprotein-ubiquinone oxidoreductase; Accepts electrons from ETF and reduces ubiquinone.
    
 0.619
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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