STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
glxBGlutamine amidotransferase, class-II protein, glxB (purF). Similar to sprot|GLXB_RHIME (46%) and to trembl|Q882P3 (49%). Glutamine amidotransferase catalyse the removal of the ammonia group from glutamine and then to transfer this group to a substrate to form a new carbon-nitrogen group. This catalytic activity is known as glutamine amidotransferase (GATase). On the basis of sequence similarities two classes of GATase domains have been identified class-I and class-II (also known as purF-type). Enzymes containing Class-II GATase domains include amido phosphoribosyltransferase, which cat [...] (302 aa)    
Predicted Functional Partners:
glxD
Glutamate synthase, large subunit. Similar to sprot|GLXD_RHIME (87%). Glutamate synthase (GltS) is a complex iron-sulphur flavoprotein that catalyses the reductive synthesis of L-glutamate from 2-oxoglutarate and L-glutamine via intramolecular channelling of ammonia, a reaction in the bacterial, yeast and plant pathways for ammonia assimilation. Pfam: Conserved region in glutamate synthase; Specificity unclear.
 
 
 0.974
glxC
Probable protein GlxC. Similar to sprot|GLXC_RHIME (59%) and to pir|A96211 (51%). Pfam (PF01493): GXGXG; Family membership.
 
  
 0.973
gltB
Ferredoxin-dependent glutamate synthase,; Specificity unclear.
   
 0.968
glnT
Glutamine synthetase III plays an essential role in the metabolism of nitrogen by catalyzing the condensation of glutamate and ammonia to form glutamine. Similar to trembl|Q98A06 (58%) and to sprot|GLN3_RHILP (38%). Pfam (PF03951): Glutamine synthetase, beta-Grasp domain Pfam(PF00120): Glutamine synthetase, catalytic domain; High confidence in function and specificity.
 
 
 0.958
azo3009
Putative DNA binding helix-turn helix protein,; Family membership.
 
   
 0.886
purL
Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.
    
 0.815
purD
Phosphoribosylamine--glycine ligase (Phosphoribosylglycinamide synthetase) (Glycinamide ribonucleotide synthetase) (GAR synthetase) (GARS); High confidence in function and specificity; Belongs to the GARS family.
    
 0.755
xanB
Probable xanthan biosynthesis protein XanB. Homology to xanB of X. campestris of 60% (sprot|XANB_XANCP(SRS)) Xanthan biosynthesis protein XanB is a multifunctional enzyme including Mannose-6-phosphate isomerase (EC 5.3.1.8) (Phosphomannose isomerase) (PMI) (Phosphohexomutase)and Mannose-1-phosphate guanylyl transferase (GDP) (EC 2.7.7.22) (GDP-mannose pyrophosphorylase) (GMP). InterPro: ADP-glucose pyrophosphorylase (IPR005835); Mannose-6-phosphate isomerase type II (IPR001538) Pfam: Nucleotidyl transferase, Mannose-6-phosphate isomerase no signal peptide no TMHs; Family membership.
    
 0.701
azo1959
Hypothetical protein SignalP reporting Non-secretory protein.
   
 
 0.579
dapE
Succinyl-diaminopimelate desuccinylase; Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls; Belongs to the peptidase M20A family. DapE subfamily.
   
 
 0.579
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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