STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
azo3023Probable outer membrane receptor TonB-dependent for iron transport. 41% AAC74533.1 InterPro: IPR000531 TonB_receptor.IPR010105; TonB_siderophor. Pfam: PF00593; TonB_dep_Rec; 1. TonB-box domain; High confidence in function and specificity. (705 aa)    
Predicted Functional Partners:
azo3024
Hypotheical secreted protein. No homology of the entire protein to the data bank. no domains predicted. no TMHs. signal peptide.
       0.773
gumB
Putative capsule polysaccharide export protein precursor.May be involved in polysaccharide polymerization or transport. 36% Poly_export. Pfam:PF02563; Poly_export; 1. Signal peptide: present; Family membership.
  
  
  0.667
wza
Conserved hypothetical polysaccharid export protein. Homology to wza of Azoarcus sp. EbN1 of 80%. Pfam: Polysaccharide biosynthesis/export protein. This is a family of periplasmic proteins involved in polysaccharide biosynthesis and/or export. No TMHs. Signal peptide present., ; Family membership.
  
  
  0.667
azo0984
Conserved hypothetical secreted protein. Homology to NE1634 of Nitrosomonas europaea of 34% (trembl|Q82U71(SRS)) No domains predicted. No TMHs Signal peptide present; Conserved hypothetical protein.
  
  
  0.646
ompA1
Outer membrane protein P.III precursor (Gonococcal protein III) (PIII). InterPro: Bacterial outer membrane protein; High confidence in function and specificity.
  
  
 0.619
azo0235
Conserved hypothetical membrane protein. Homology to an orf of Rubrivivax gelatinosus of 55% (gi|47575633|ref|ZP_00245668.1|(NBCI ENTREZ)). No domains predicted. No signal peptide. 1 TMHs; Conserved hypothetical protein.
  
 
 0.608
tolA
Conserved hypothetical membrane protein. Homology to tolA of N. europaea of 39% (trembl|Q82XP0). no domains predicted InterPro: Proline-rich region (IPR000694) no signal peptide 1 TMHs; Conserved hypothetical protein.
  
 
 0.608
tonB1
Putative TonB protein. Homology to tonb2 of P. aeruginosa of 39% (TREMBL:Q9RMT3). To complete transport of bound iron across the inner membrane, a second receptor complex is needed. The major component of this is tonB, a 27kDa protein that facilitates energy transfer from the proton motive force to outer receptors Pfam: Gram-negative bacterial TonB protein no signal peptide 1 TMH; Function unclear.
  
 
 0.608
azo0708
Conserved hypothetical secreted protein. Homology to ne1626 of N. europaea of 46% (trembl|Q82U75) no domains predicted signal peptide TMH in signal peptide; Conserved hypothetical protein.
  
 
 0.608
tonB2
Periplasmic biopolymer transport protein linking inner and outer membranes; Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins. Belongs to the TonB family.
  
 
 0.608
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
Server load: medium (62%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.