STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
azo3042NADPH quinone oxidoreductase, putative; ZP_00167050: 52% identity; 70% similarity. Quinone oxidoreductase (EC 1.6.5.5) (NADPH:quinone reductase) (Zeta- crystallin). DOES NOT HAVE ALCOHOL DEHYDROGENASE ACTIVITY. BINDS NADP AND ACTS THROUGH A ONE-ELECTRON TRANSFER PROCESS. ORTHOQUINONES ARE THE BEST SUBSTRATES. MAY ACT IN THE DETOXIFICATION OF XENOBIOTICS (BY SIMILARITY). InterPro: Zinc-containing alcohol dehydrogenase superfamily InterPro:IPR002085; Adh_zn_family. Pfam:PF00107; ADH_zinc_N TIGRFAM: 2A0302: arginine/ornithine antiporter tdh: L-threonine 3-dehydrogenase; Function unclear. (326 aa)    
Predicted Functional Partners:
azo2493
Conserved hypothetical protein; Entry name:- TREMBL:Q8XXS1 InterPro IPR002539; MaoC_dehydratas. Pfam PF01575; MaoC_dehydratas; 1. Identities = 74/154 (48%) Prediction: Non-secretory protein Signal peptide probability: 0.000 Number of predicted TMHs: 0.
 0.913
paaG4
Putative enoyl-CoA hydratase; COULD POSSIBLY OXIDIZES FATTY ACIDS USING SPECIFIC COMPONENTS (BY SIMILARITY). catalytic activity:-(3s)-3-hydroxyacyl-coa = trans-2(or 3)-enoyl- coa + H(2)o. Entry name:- SWISSPROT:PAAG_ECOLI InterPro:-IPR001753; EnCoA_hydrtse. Pfam:- PF00378; ECH; 1. Identities = 72/262 (27%) Number of predicted TMHs: 0; Family membership; Belongs to the enoyl-CoA hydratase/isomerase family.
   
 0.793
fadD2
Long-chain-fatty-acid--CoA ligase (EC 6.2.1.3) (Long-chain acyl-CoA synthetase). Esterification concomitant with transport of exogenous long-chain fatty acids into metabolically active CoA thioesters for subsequent degradation or incorporation into phospholipids, TREMBL:Q89CF2 (46% identity); TREMBL:Q89CJ5 (44% identity). Pfam (PF00501): AMP-binding enzyme; Specificity unclear.
 
 
 0.781
nagAa
Naphthalene 12-dioxygenase system ferredoxin--NAD(+) reductase component COMPONENT OF NAPHTHALENE DIOXYGENASE (NDO) MULTICOMPONENT ENZYME SYSTEM WHICH CATALYZES THE INCORPORATION OF BOTH ATOMS OF MOLECULAR OXYGEN INTO NAPHTHALENE TO FORM CIS- NAPHTHALENE DIHYDRODIOL. TRANSFERS ELECTRONS FROM FERREDOXIN (NDOA) TO NADH; High confidence in function and specificity.
     
 0.781
azo1695
Putative AMP-binding protein; Similar to TREMBL:Q9HWI3 (58% identity); TREMBL:Q89LN0 (56% identity); TREMBL:Q986M2 (56% identity). InterPro (IPR000873): AMP-dependent synthetase and ligase. Pfam (PF00501): AMP-binding enzyme; Function unclear.
 
 
 0.773
azo1985
Putative AMP-binding protein; Similar to TREMBL:Q89PS8 (59% identity). InterPro (IPR000873): AMP-dependent synthetase and ligase. Pfam (PF00501): AMP-binding enzyme; Function unclear.
 
 
 0.768
aas
AAS bifunctional protein [Includes: 2-acylglycerophosphoethanolamine acyltransferase (2-acyl-GPE acyltransferase); Acyl-acyl carrier protein synthetase (Acyl-ACP synthetase)]. PLAYS A ROLE IN LYSOPHOSPHOLIPID ACYLATION. TRANSFERS FATTY ACIDS TO THE 1-POSITION VIA AN ENZYME-BOUND ACYL-ACP INTERMEDIATE IN THE PRESENCE OF ATP AND MG(2+). ITS PHYSIOLOGICAL FUNCTION IS TO REGENERATE PTDETN FROM 2-ACYL-GPE FORMED BY TRANSACYLATION REACTIONS OR DEGRADATION BY PHOSPHOLIPASE A1, TREMBL:Q8FEA6 (52% identity); SWISSPROT:P31119 (52% identity). Pfam (PF00501): AMP-binding enzyme. Pfam (PF01553): Ac [...]
   
 0.756
fadD1
Long-chain-fatty-acid-CoA ligase; Esterification concomitant with transport of exogenous long-chain fatty acids into metabolically active CoA thioesters for subsequent degradation or incorporation into phospholipids, TREMBL:Q7NY16 (61% identity); TREMBL:Q7WLG0 (63% identity). InterPro (IPR000873): AMP-dependent synthetase and ligase Pfam (PF00501): AMP-binding enzyme; High confidence in function and specificity.
   
 0.737
ybgC
Probable thioesterase; Hypothetical protein HI0386. TREMBL:Q84HI6: 48% identity, 66% similarity 4-hydroxybenzoyl-CoA thioesterase is a protein of 141 amino-acid residues that assemble as an homotetramer. An aspartate in the N-terminal domain is thought to participate in the catalytic mechanism 4-hydroxybenzoyl-CoA + H2 O = 4-hydroxybenzoate + CoA IPR006683; Thioesterase superfamily IPR006684; 4-hydroxybenzoyl-CoA thioesterase Pfam:PF03061; 4HBT; No transmembrane helices (TMHMM predicted) TIGR00051: conserved hypothetical protein; High confidence in function and specificity.
       0.737
fadD3
Long-chain fatty-acid-CoA ligase; Esterification, concomitant with transport, of exogenous long-chain fatty acids into metabolically active CoA thioesters for subsequent degradation or incorporation into phospholipids, TREMBL:Q9F9U4 (61% identity); TREMBL:Q7NX49 (69% identity). Pfam (PF00501): AMP-binding enzyme; High confidence in function and specificity.
   
 0.737
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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