STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
livM3Putative branched-chain amino acid transport permease. Homology to livM of E. coli of 31% as well as genes coding for a new pathway of aerobic benzoate meabolisme in A. evansii (77%). Part of the binding-protein-dependent transport system for branched-chain amino acids. Probably responsible for the translocation of the substrates across the membrane. Pfam: Branched-chain amino acid transport system. probable signal peptide probable 8 TMHs; Specificity unclear. (326 aa)    
Predicted Functional Partners:
azo3049
ABC transporter permease protein; Branched-chain amino acid transport system typically composed of a periplasmic substrate-binding protein, one or two reciprocally homologous integral inner-membrane proteins and one or two peripheral membrane ATP-binding proteins that couple energy to the active transport system.The integral inner-membrane proteins translocate the substrate across the membrane. Similar to trembl|Q84HI2 (91%), to trembl|Q89VI1 (47%), to sprot|LIVH_ECOLI (27%) and to sprot|BRAD_PSEAE (30%). Pfam (PF02653): Binding-system dependent bacterial transporters (araH, livH/limM [...]
 
 0.999
livG1
ATP-binding cassette (ABC) transporters are multidomain membrane proteins, responsible for the controlled efflux and influx of substances (allocrites) across cellular membranes. ATP-binding protein is for coupling the energy of ATP hydrolysis to conformational changes in the transmembrane domains. Similar to trembl|Q84HI3 (79%) and to sprot|LIVG_ECOLI (37%). Pfam (PF00005): ABC transporter ProSite (PS50101): ATP/GTP-binding site motif A (P-loop) Smart (SM00382): AAA ATPase superfamily; Specificity unclear.
 
  0.985
azo1125
ABC transporter permease protein; Branched-chain amino acid transport system typically composed of a periplasmic substrate-binding protein, one or two reciprocally homologous integral inner-membrane proteins and one or two peripheral membrane ATP-binding proteins that couple energy to the active transport system.The integral inner-membrane proteins translocate the substrate across the membrane. Similar to trembl|Q7W060 (64%) and to sprot|LIVH_ECOLI (24%). Pfam (PF02653): Branched-chain amino acid transport system / permease component TMHMM reporting eight Tmhelix; Specificity unclear.
 
 0.978
azo3046
ATP-binding cassette (ABC) transporters are multidomain membrane proteins, responsible for the controlled efflux and influx of substances (allocrites) across cellular membranes. ATP-binding protein is for coupling the energy of ATP hydrolysis to conformational changes in the transmembrane domains. Similar to trembl|Q84HI4 (80%) and to trembl|Q89VH8 (45%). Pfam (PF00005): ABC transporter Smart (SM00382): AAA ATPase superfamily ProSite (PS50101): ATP/GTP-binding site motif A (P-loop); Specificity unclear.
 
 0.970
azo1127
ATP-binding cassette (ABC) transporters are multidomain membrane proteins, responsible for the controlled efflux and influx of substances (allocrites) across cellular membranes. ATP binding domains are responsible for coupling the energy of ATP hydrolysis to conformational changes in the ransmembrane domains. Similar to trembl|Q7W058 (49%) and to sprot|LIVG_ECOLI (39%). Pfam (PF00005): ABC transporter Smart (SM00382): AAA ATPase superfamily; Specificity unclear.
 
  0.927
livJ
Putative leucine-specific binding protein; In enteric bacteria such E. coli and Salmonella typhimurium, periplasmic binding proteins are found to participate in the transport of amino acids, sugars and ions. Leucine-specific binding protein are coded by livK and livJ. Similar trembl|Q93FB9 (84%) and to sprot|LIVJ_ECOLI (21%). Pfam (PF01094): Receptor family ligand binding region Pfam (PF04392): Protein of unknown function (DUF534) SignalP reporting Signal peptide; Specificity unclear.
 
 
  0.920
azo0120
ABC transporter permease protein; Branched-chain amino acid transport system typically composed of a periplasmic substrate-binding protein, one or two reciprocally homologous integral inner-membrane proteins and one or two peripheral membrane ATP-binding proteins that couple energy to the active transport system.The integral inner-membrane proteins translocate the substrate across the membrane. Similar to trembl|Q92LQ5 (71%) and to trembl|Q8XU52 (69%). Pfam (PF02653): Binding-system dependent bacterial transporters (araH, livH/limM families) TMHMM reporting eight Tmhelix; Specificity u [...]
 
 
  0.919
livH
ABC transporter permease protein; Branched-chain amino acid transport system typically composed of a periplasmic substrate-binding protein, one or two reciprocally homologous integral inner-membrane proteins and one or two peripheral membrane ATP-binding proteins that couple energy to the active transport system.The integral inner-membrane proteins translocate the substrate across the membrane. Similar trembl|Q7NXX3 (60%), to sprot|BRAD_PSEAE (47%) and to sprot|LIVH_ECOLI (44%). Pfam (PF02653): Branched-chain amino acid transport system / permease component TMHMM reporting seven Tmheli [...]
 
 
  0.909
livG2
ABC transporter ATP-binding protein; Probable high-affinity branched-chain amino acid transport ATP-binding protein BraF. ATP-binding cassette (ABC) transporters are multidomain membrane proteins,responsible for the controlled efflux and influx of substances (allocrites) across cellular membranes. ATP-binding protein is for coupling the energy of ATP hydrolysis to conformational changes in the transmembrane domains. BraF is a COMPONENT OF THE HIGH AFFINITY LEUCINE ISOLEUCINE VALINE TRANSPORT SYSTEM (LIV-I) WHICH IS OPERATIVE WITHOUT NA(+) AND IS SPECIFIC FOR ALANINE AND THREONINE IN AD [...]
 
  0.903
azo1128
ATP-binding cassette (ABC) transporters are multidomain membrane proteins, responsible for the controlled efflux and influx of substances (allocrites) across cellular membranes. ATP-binding protein is for coupling the energy of ATP hydrolysis to conformational changes in the transmembrane domains. Similar to trembl|Q7W057 (65%) and to trembl|Q84HI4 (49%). Smart (SM00382): ATPase superfamily Pfam (PF00005): ABC transporter ProSite (PS50101): ATP/GTP-binding site motif A (P-loop); Specificity unclear.
 
 0.878
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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