STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
bzdAProbable benzoate-coa ligase; Entry name :- TREMBL:Q84HI0 Entry name :-TREMBL:Q8VUF1 InterPro IPR010071; AA_adenyl_dom. IPR000873; AMP-bind. IPR010192; MenE. Pfam PF00501; AMP-binding; 1 Identities = 414/532 (77%) Prediction: Non-secretory protein Signal peptide probability: 0.000 Number of predicted TMHs: 0; Family membership. (532 aa)    
Predicted Functional Partners:
azo3056
Probable enoyl-coa-hydratase/isomerase; Activity:- (3S)-3-hydroxyacyl-CoA = trans-2(or 3)-enoyl-CoA + H2O Entry name :- TREMBL:Q84HH6 InterPro :-IPR001753; EnCoA_hydrtse. Pfam:- PF00378; ECH; 1. Number of predicted TMHs: 0 Identities = 452/553 (81%); Family membership.
 
 
  0.843
boxA
Benzoyl-CoA oxygenase component A. 84% 4Fe4S_ferredoxin. IPR001709; FPN_cyt_redctse. IPR001433; Oxred_FAD/NAD(P). Pfam:PF00037; Fer4; 2. PF00175; NAD_binding_1; 1; High confidence in function and specificity.
 
  
 0.811
abmA
2-amninobenzoyl-CoA monooxygenase/reductase (EC 1.14.13.40) Homology to abmA of A. evansii of 86% (trembl|Q93FB8(SRS). natural fusion protein of a monooxygenase and a reductase; contains flavin. Pfam: Monooxygnease; NADH:flavin oxidoreductase/NADH oxidorecutase. no signal peptide. no TMHs; High confidence in function and specificity.
 
 0.802
pepM
Phosphoenolpyruvate phosphomutase precursor(Phosphoenolpyruvate mutase) (PEP mutase) (PEP phosphomutase).FORMATION OF A CARBON-PHOSPHORUS BOND BY CONVERTING PHOSPHOENOLPYRUVATE (PEP) TO PHOSPHONOPYRUVATE (P-PYR). 34% Isocit_lyase_ph; High confidence in function and specificity.
 
 
 0.801
azo3053
Conserved hypothetical protein. Homology to an orf of A. evnasii of 79% (trembl|Q84HH9). no domains predicted. no signal peptide. no TMHS.
 
     0.799
boxB
Benzoyl-CoA oxygenase component B. 85%; Function unclear.
 
     0.780
azo3045
Probable lactonase; TREMBL:Q84HI5: 83% identity, 89% similarity from Azoarcus evansii (gene name refereed as ORF2) Haloalkane dehalogenase (EC 3.8.1.5). Catalyzes hydrolytic cleavage of carbon-halogen bonds in halogenated aliphatic compounds leading to the formation of the corresponding primary alcohols halide ions and protons. Has a broad substrate specificity which includes mono- and di- chlorinated and brominated alkanes. The highest activity was found with 12-dibromoethane whereas low activity was measured with the analog 12-dichloroethane. InterPro: Alpha/beta hydrolase fold Descr [...]
 
  
  0.765
aroK-2
Conserved hypothetical protein; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family.
 
 
 
 0.755
fadB1
Probable enoyl-CoA hydratase / 3-hydroxyacyl-CoA dehydrogenase; Alpha-subunit of fatty acid oxidation complex. Entry name TREMBL:Q8G968 Prim. accession # Q8G968 Identities = 373/642 (58%) InterPro IPR006108; 3HCDH_C. IPR006176; 3HCDH_N. Prediction: Non-secretory protein Signal peptide probability: 0.000 Number of predicted TMHs: 0 IPR008927; 6DGDH_C_like. IPR001753; EnCoA_hydrtse. Pfam PF00725; 3HCDH; 1. PF02737; 3HCDH_N; 1. PF00378; ECH; 1; Family membership.
  
 
 0.753
fadB2
Short-chain enoyl-CoA hydratase activity. Activity:- 3S)-3-hydroxyacyl-CoA = trans-2(or 3)-enoyl-CoA + H2O Entry name TREMBL:Q8P986 Prim. accession # Q8P986 InterPro IPR006108; 3HCDH_C. IPR006176; 3HCDH_N. IPR008927; 6DGDH_C_like. IPR001753; EnCoA_hydrtse. IPR000205; NAD_BS. Pfam PF00725; 3HCDH; 1. PF02737; 3HCDH_N; 1. PF00378; ECH; 1. Identities = 468/796 (58%) Prediction: Signal peptide Signal peptide probability: 0.980 Number of predicted TMHs: 0; Family membership.
  
 
 0.753
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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