| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| aroK-2 | azo3045 | azo3055 | azo3045 | Conserved hypothetical protein; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. | Probable lactonase; TREMBL:Q84HI5: 83% identity, 89% similarity from Azoarcus evansii (gene name refereed as ORF2) Haloalkane dehalogenase (EC 3.8.1.5). Catalyzes hydrolytic cleavage of carbon-halogen bonds in halogenated aliphatic compounds leading to the formation of the corresponding primary alcohols halide ions and protons. Has a broad substrate specificity which includes mono- and di- chlorinated and brominated alkanes. The highest activity was found with 12-dibromoethane whereas low activity was measured with the analog 12-dichloroethane. InterPro: Alpha/beta hydrolase fold Descr [...] | 0.685 |
| aroK-2 | azo3053 | azo3055 | azo3053 | Conserved hypothetical protein; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. | Conserved hypothetical protein. Homology to an orf of A. evnasii of 79% (trembl|Q84HH9). no domains predicted. no signal peptide. no TMHS. | 0.821 |
| aroK-2 | azo3054 | azo3055 | azo3054 | Conserved hypothetical protein; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. | Aldehyde dehydrogenase (NAD+). Homology to the aldehyce dehydrogenase of the of the benzoate gene cluster of A. evansii of 81% (trembl|Q84HH8). Aldehyde dehydrogenases are enzymes which oxidize a wide variety of aliphatic and aromatic aldehydes using NADP as a cofactor. Here clustered with genes involved in the aerobic benzoate metabolism. InterPro: Aldehyde dehydrogenase family (IPR002086) Pfam: Aldehyde dehydrogenase family no signal peptide no TMHs; High confidence in function and specificity. | 0.540 |
| aroK-2 | azo3056 | azo3055 | azo3056 | Conserved hypothetical protein; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. | Probable enoyl-coa-hydratase/isomerase; Activity:- (3S)-3-hydroxyacyl-CoA = trans-2(or 3)-enoyl-CoA + H2O Entry name :- TREMBL:Q84HH6 InterPro :-IPR001753; EnCoA_hydrtse. Pfam:- PF00378; ECH; 1. Number of predicted TMHs: 0 Identities = 452/553 (81%); Family membership. | 0.935 |
| aroK-2 | boxA | azo3055 | azo3058 | Conserved hypothetical protein; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. | Benzoyl-CoA oxygenase component A. 84% 4Fe4S_ferredoxin. IPR001709; FPN_cyt_redctse. IPR001433; Oxred_FAD/NAD(P). Pfam:PF00037; Fer4; 2. PF00175; NAD_binding_1; 1; High confidence in function and specificity. | 0.862 |
| aroK-2 | boxB | azo3055 | azo3057 | Conserved hypothetical protein; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. | Benzoyl-CoA oxygenase component B. 85%; Function unclear. | 0.872 |
| aroK-2 | bzdA | azo3055 | azo3052 | Conserved hypothetical protein; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. | Probable benzoate-coa ligase; Entry name :- TREMBL:Q84HI0 Entry name :-TREMBL:Q8VUF1 InterPro IPR010071; AA_adenyl_dom. IPR000873; AMP-bind. IPR010192; MenE. Pfam PF00501; AMP-binding; 1 Identities = 414/532 (77%) Prediction: Non-secretory protein Signal peptide probability: 0.000 Number of predicted TMHs: 0; Family membership. | 0.755 |
| aroK-2 | livJ | azo3055 | azo3050 | Conserved hypothetical protein; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. | Putative leucine-specific binding protein; In enteric bacteria such E. coli and Salmonella typhimurium, periplasmic binding proteins are found to participate in the transport of amino acids, sugars and ions. Leucine-specific binding protein are coded by livK and livJ. Similar trembl|Q93FB9 (84%) and to sprot|LIVJ_ECOLI (21%). Pfam (PF01094): Receptor family ligand binding region Pfam (PF04392): Protein of unknown function (DUF534) SignalP reporting Signal peptide; Specificity unclear. | 0.541 |
| azo3045 | aroK-2 | azo3045 | azo3055 | Probable lactonase; TREMBL:Q84HI5: 83% identity, 89% similarity from Azoarcus evansii (gene name refereed as ORF2) Haloalkane dehalogenase (EC 3.8.1.5). Catalyzes hydrolytic cleavage of carbon-halogen bonds in halogenated aliphatic compounds leading to the formation of the corresponding primary alcohols halide ions and protons. Has a broad substrate specificity which includes mono- and di- chlorinated and brominated alkanes. The highest activity was found with 12-dibromoethane whereas low activity was measured with the analog 12-dichloroethane. InterPro: Alpha/beta hydrolase fold Descr [...] | Conserved hypothetical protein; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. | 0.685 |
| azo3045 | azo3051 | azo3045 | azo3051 | Probable lactonase; TREMBL:Q84HI5: 83% identity, 89% similarity from Azoarcus evansii (gene name refereed as ORF2) Haloalkane dehalogenase (EC 3.8.1.5). Catalyzes hydrolytic cleavage of carbon-halogen bonds in halogenated aliphatic compounds leading to the formation of the corresponding primary alcohols halide ions and protons. Has a broad substrate specificity which includes mono- and di- chlorinated and brominated alkanes. The highest activity was found with 12-dibromoethane whereas low activity was measured with the analog 12-dichloroethane. InterPro: Alpha/beta hydrolase fold Descr [...] | Conserved hypothetical protein. Homology Daro03002253 of Dechloromonas aromatica of 43% (gi|53730397|ref|ZP_00151095.2|(NBCI ENTREZ)). Pfam: Hemerythrin HHE cation binding domain. Iteration of the HHE family found it to be related to Hemerythrin. It also demonstrated that what has been described as a single domain in fact consists of two cation binding domains. Members of this family occur all across nature and are involved in a variety of processes. For instance, in Nereis diversicolor MP2_NERDI binds Cadmium so as to protect the organism from toxicity. However Hemerythrin is classica [...] | 0.467 |
| azo3045 | azo3053 | azo3045 | azo3053 | Probable lactonase; TREMBL:Q84HI5: 83% identity, 89% similarity from Azoarcus evansii (gene name refereed as ORF2) Haloalkane dehalogenase (EC 3.8.1.5). Catalyzes hydrolytic cleavage of carbon-halogen bonds in halogenated aliphatic compounds leading to the formation of the corresponding primary alcohols halide ions and protons. Has a broad substrate specificity which includes mono- and di- chlorinated and brominated alkanes. The highest activity was found with 12-dibromoethane whereas low activity was measured with the analog 12-dichloroethane. InterPro: Alpha/beta hydrolase fold Descr [...] | Conserved hypothetical protein. Homology to an orf of A. evnasii of 79% (trembl|Q84HH9). no domains predicted. no signal peptide. no TMHS. | 0.642 |
| azo3045 | azo3054 | azo3045 | azo3054 | Probable lactonase; TREMBL:Q84HI5: 83% identity, 89% similarity from Azoarcus evansii (gene name refereed as ORF2) Haloalkane dehalogenase (EC 3.8.1.5). Catalyzes hydrolytic cleavage of carbon-halogen bonds in halogenated aliphatic compounds leading to the formation of the corresponding primary alcohols halide ions and protons. Has a broad substrate specificity which includes mono- and di- chlorinated and brominated alkanes. The highest activity was found with 12-dibromoethane whereas low activity was measured with the analog 12-dichloroethane. InterPro: Alpha/beta hydrolase fold Descr [...] | Aldehyde dehydrogenase (NAD+). Homology to the aldehyce dehydrogenase of the of the benzoate gene cluster of A. evansii of 81% (trembl|Q84HH8). Aldehyde dehydrogenases are enzymes which oxidize a wide variety of aliphatic and aromatic aldehydes using NADP as a cofactor. Here clustered with genes involved in the aerobic benzoate metabolism. InterPro: Aldehyde dehydrogenase family (IPR002086) Pfam: Aldehyde dehydrogenase family no signal peptide no TMHs; High confidence in function and specificity. | 0.406 |
| azo3045 | azo3056 | azo3045 | azo3056 | Probable lactonase; TREMBL:Q84HI5: 83% identity, 89% similarity from Azoarcus evansii (gene name refereed as ORF2) Haloalkane dehalogenase (EC 3.8.1.5). Catalyzes hydrolytic cleavage of carbon-halogen bonds in halogenated aliphatic compounds leading to the formation of the corresponding primary alcohols halide ions and protons. Has a broad substrate specificity which includes mono- and di- chlorinated and brominated alkanes. The highest activity was found with 12-dibromoethane whereas low activity was measured with the analog 12-dichloroethane. InterPro: Alpha/beta hydrolase fold Descr [...] | Probable enoyl-coa-hydratase/isomerase; Activity:- (3S)-3-hydroxyacyl-CoA = trans-2(or 3)-enoyl-CoA + H2O Entry name :- TREMBL:Q84HH6 InterPro :-IPR001753; EnCoA_hydrtse. Pfam:- PF00378; ECH; 1. Number of predicted TMHs: 0 Identities = 452/553 (81%); Family membership. | 0.764 |
| azo3045 | boxA | azo3045 | azo3058 | Probable lactonase; TREMBL:Q84HI5: 83% identity, 89% similarity from Azoarcus evansii (gene name refereed as ORF2) Haloalkane dehalogenase (EC 3.8.1.5). Catalyzes hydrolytic cleavage of carbon-halogen bonds in halogenated aliphatic compounds leading to the formation of the corresponding primary alcohols halide ions and protons. Has a broad substrate specificity which includes mono- and di- chlorinated and brominated alkanes. The highest activity was found with 12-dibromoethane whereas low activity was measured with the analog 12-dichloroethane. InterPro: Alpha/beta hydrolase fold Descr [...] | Benzoyl-CoA oxygenase component A. 84% 4Fe4S_ferredoxin. IPR001709; FPN_cyt_redctse. IPR001433; Oxred_FAD/NAD(P). Pfam:PF00037; Fer4; 2. PF00175; NAD_binding_1; 1; High confidence in function and specificity. | 0.686 |
| azo3045 | boxB | azo3045 | azo3057 | Probable lactonase; TREMBL:Q84HI5: 83% identity, 89% similarity from Azoarcus evansii (gene name refereed as ORF2) Haloalkane dehalogenase (EC 3.8.1.5). Catalyzes hydrolytic cleavage of carbon-halogen bonds in halogenated aliphatic compounds leading to the formation of the corresponding primary alcohols halide ions and protons. Has a broad substrate specificity which includes mono- and di- chlorinated and brominated alkanes. The highest activity was found with 12-dibromoethane whereas low activity was measured with the analog 12-dichloroethane. InterPro: Alpha/beta hydrolase fold Descr [...] | Benzoyl-CoA oxygenase component B. 85%; Function unclear. | 0.747 |
| azo3045 | bzdA | azo3045 | azo3052 | Probable lactonase; TREMBL:Q84HI5: 83% identity, 89% similarity from Azoarcus evansii (gene name refereed as ORF2) Haloalkane dehalogenase (EC 3.8.1.5). Catalyzes hydrolytic cleavage of carbon-halogen bonds in halogenated aliphatic compounds leading to the formation of the corresponding primary alcohols halide ions and protons. Has a broad substrate specificity which includes mono- and di- chlorinated and brominated alkanes. The highest activity was found with 12-dibromoethane whereas low activity was measured with the analog 12-dichloroethane. InterPro: Alpha/beta hydrolase fold Descr [...] | Probable benzoate-coa ligase; Entry name :- TREMBL:Q84HI0 Entry name :-TREMBL:Q8VUF1 InterPro IPR010071; AA_adenyl_dom. IPR000873; AMP-bind. IPR010192; MenE. Pfam PF00501; AMP-binding; 1 Identities = 414/532 (77%) Prediction: Non-secretory protein Signal peptide probability: 0.000 Number of predicted TMHs: 0; Family membership. | 0.765 |
| azo3045 | livJ | azo3045 | azo3050 | Probable lactonase; TREMBL:Q84HI5: 83% identity, 89% similarity from Azoarcus evansii (gene name refereed as ORF2) Haloalkane dehalogenase (EC 3.8.1.5). Catalyzes hydrolytic cleavage of carbon-halogen bonds in halogenated aliphatic compounds leading to the formation of the corresponding primary alcohols halide ions and protons. Has a broad substrate specificity which includes mono- and di- chlorinated and brominated alkanes. The highest activity was found with 12-dibromoethane whereas low activity was measured with the analog 12-dichloroethane. InterPro: Alpha/beta hydrolase fold Descr [...] | Putative leucine-specific binding protein; In enteric bacteria such E. coli and Salmonella typhimurium, periplasmic binding proteins are found to participate in the transport of amino acids, sugars and ions. Leucine-specific binding protein are coded by livK and livJ. Similar trembl|Q93FB9 (84%) and to sprot|LIVJ_ECOLI (21%). Pfam (PF01094): Receptor family ligand binding region Pfam (PF04392): Protein of unknown function (DUF534) SignalP reporting Signal peptide; Specificity unclear. | 0.637 |
| azo3051 | azo3045 | azo3051 | azo3045 | Conserved hypothetical protein. Homology Daro03002253 of Dechloromonas aromatica of 43% (gi|53730397|ref|ZP_00151095.2|(NBCI ENTREZ)). Pfam: Hemerythrin HHE cation binding domain. Iteration of the HHE family found it to be related to Hemerythrin. It also demonstrated that what has been described as a single domain in fact consists of two cation binding domains. Members of this family occur all across nature and are involved in a variety of processes. For instance, in Nereis diversicolor MP2_NERDI binds Cadmium so as to protect the organism from toxicity. However Hemerythrin is classica [...] | Probable lactonase; TREMBL:Q84HI5: 83% identity, 89% similarity from Azoarcus evansii (gene name refereed as ORF2) Haloalkane dehalogenase (EC 3.8.1.5). Catalyzes hydrolytic cleavage of carbon-halogen bonds in halogenated aliphatic compounds leading to the formation of the corresponding primary alcohols halide ions and protons. Has a broad substrate specificity which includes mono- and di- chlorinated and brominated alkanes. The highest activity was found with 12-dibromoethane whereas low activity was measured with the analog 12-dichloroethane. InterPro: Alpha/beta hydrolase fold Descr [...] | 0.467 |
| azo3051 | azo3053 | azo3051 | azo3053 | Conserved hypothetical protein. Homology Daro03002253 of Dechloromonas aromatica of 43% (gi|53730397|ref|ZP_00151095.2|(NBCI ENTREZ)). Pfam: Hemerythrin HHE cation binding domain. Iteration of the HHE family found it to be related to Hemerythrin. It also demonstrated that what has been described as a single domain in fact consists of two cation binding domains. Members of this family occur all across nature and are involved in a variety of processes. For instance, in Nereis diversicolor MP2_NERDI binds Cadmium so as to protect the organism from toxicity. However Hemerythrin is classica [...] | Conserved hypothetical protein. Homology to an orf of A. evnasii of 79% (trembl|Q84HH9). no domains predicted. no signal peptide. no TMHS. | 0.584 |
| azo3051 | bzdA | azo3051 | azo3052 | Conserved hypothetical protein. Homology Daro03002253 of Dechloromonas aromatica of 43% (gi|53730397|ref|ZP_00151095.2|(NBCI ENTREZ)). Pfam: Hemerythrin HHE cation binding domain. Iteration of the HHE family found it to be related to Hemerythrin. It also demonstrated that what has been described as a single domain in fact consists of two cation binding domains. Members of this family occur all across nature and are involved in a variety of processes. For instance, in Nereis diversicolor MP2_NERDI binds Cadmium so as to protect the organism from toxicity. However Hemerythrin is classica [...] | Probable benzoate-coa ligase; Entry name :- TREMBL:Q84HI0 Entry name :-TREMBL:Q8VUF1 InterPro IPR010071; AA_adenyl_dom. IPR000873; AMP-bind. IPR010192; MenE. Pfam PF00501; AMP-binding; 1 Identities = 414/532 (77%) Prediction: Non-secretory protein Signal peptide probability: 0.000 Number of predicted TMHs: 0; Family membership. | 0.752 |