| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| azo1044 | azo2910 | azo1044 | azo2910 | Conserved hypothetical membrane protein. Homology to ebA4769 of Azoarcus sp. EbN1 of 53% (gnl|keqq|eba:ebA4769(KEGG)). Pfam: Cobalt transport protein. signal peptide. 3 TMHs; Family membership. | ATP-binding cassette (ABC) transporters form a large family of proteins responsible for translocation of a variety of compounds across biological membranes. They are composed of two transmembrane domains responsible for binding and transport and two nucleotide-binding domains responsible for coupling the energy of ATP hydrolysis to conformational changes in the TMDs, TREMBL:Q8FZX0 (58% identity); TREMBL:Q8U6Y9 (59% identity). InterPro (IPR003593): AAA ATPase. InterPro (IPR001687): ATP/GTP-binding site motif A (P-loop). InterPro (IPR003439): ABC transporter. Pfam (PF00005): ABC transpor [...] | 0.827 |
| azo1044 | azo3063 | azo1044 | azo3063 | Conserved hypothetical membrane protein. Homology to ebA4769 of Azoarcus sp. EbN1 of 53% (gnl|keqq|eba:ebA4769(KEGG)). Pfam: Cobalt transport protein. signal peptide. 3 TMHs; Family membership. | Conserved hypothetical membrane protein. Homology to CV2531 of C. violaceum of 37%. Tigrfam: 2A78: Carboxylate/Amino Acid/Amine Tranporter. Pfam: Integral membrane protein DUF6. probable 10 TMHs. probable signal peptide; Conserved hypothetical protein. | 0.435 |
| azo2371 | azo3063 | azo2371 | azo3063 | 30S ribosomal protein S4, truncated. Homology of aa 1 to 108 with rpsD of N. europaea of 67% (sprot|RS4B_NITEU(SRS)). With S5 and S12 plays an important role in translational accuracy (By similarity). Pfam: Ribosomal protein S4/S9 n-terminal domain. no signal peptide. no TMHs; Family membership; Belongs to the universal ribosomal protein uS4 family. | Conserved hypothetical membrane protein. Homology to CV2531 of C. violaceum of 37%. Tigrfam: 2A78: Carboxylate/Amino Acid/Amine Tranporter. Pfam: Integral membrane protein DUF6. probable 10 TMHs. probable signal peptide; Conserved hypothetical protein. | 0.455 |
| azo2910 | azo1044 | azo2910 | azo1044 | ATP-binding cassette (ABC) transporters form a large family of proteins responsible for translocation of a variety of compounds across biological membranes. They are composed of two transmembrane domains responsible for binding and transport and two nucleotide-binding domains responsible for coupling the energy of ATP hydrolysis to conformational changes in the TMDs, TREMBL:Q8FZX0 (58% identity); TREMBL:Q8U6Y9 (59% identity). InterPro (IPR003593): AAA ATPase. InterPro (IPR001687): ATP/GTP-binding site motif A (P-loop). InterPro (IPR003439): ABC transporter. Pfam (PF00005): ABC transpor [...] | Conserved hypothetical membrane protein. Homology to ebA4769 of Azoarcus sp. EbN1 of 53% (gnl|keqq|eba:ebA4769(KEGG)). Pfam: Cobalt transport protein. signal peptide. 3 TMHs; Family membership. | 0.827 |
| azo2910 | azo3063 | azo2910 | azo3063 | ATP-binding cassette (ABC) transporters form a large family of proteins responsible for translocation of a variety of compounds across biological membranes. They are composed of two transmembrane domains responsible for binding and transport and two nucleotide-binding domains responsible for coupling the energy of ATP hydrolysis to conformational changes in the TMDs, TREMBL:Q8FZX0 (58% identity); TREMBL:Q8U6Y9 (59% identity). InterPro (IPR003593): AAA ATPase. InterPro (IPR001687): ATP/GTP-binding site motif A (P-loop). InterPro (IPR003439): ABC transporter. Pfam (PF00005): ABC transpor [...] | Conserved hypothetical membrane protein. Homology to CV2531 of C. violaceum of 37%. Tigrfam: 2A78: Carboxylate/Amino Acid/Amine Tranporter. Pfam: Integral membrane protein DUF6. probable 10 TMHs. probable signal peptide; Conserved hypothetical protein. | 0.485 |
| azo2910 | cbiQ | azo2910 | azo2221 | ATP-binding cassette (ABC) transporters form a large family of proteins responsible for translocation of a variety of compounds across biological membranes. They are composed of two transmembrane domains responsible for binding and transport and two nucleotide-binding domains responsible for coupling the energy of ATP hydrolysis to conformational changes in the TMDs, TREMBL:Q8FZX0 (58% identity); TREMBL:Q8U6Y9 (59% identity). InterPro (IPR003593): AAA ATPase. InterPro (IPR001687): ATP/GTP-binding site motif A (P-loop). InterPro (IPR003439): ABC transporter. Pfam (PF00005): ABC transpor [...] | Putative cobalt transport system permease protein; Part of the ABC transporter complex cbiKMQO involved in cobalt import. Similar to the cobalt transport membrane protein, CbiQ in A. pleuropneumoniae; Function unclear. | 0.827 |
| azo3063 | azo1044 | azo3063 | azo1044 | Conserved hypothetical membrane protein. Homology to CV2531 of C. violaceum of 37%. Tigrfam: 2A78: Carboxylate/Amino Acid/Amine Tranporter. Pfam: Integral membrane protein DUF6. probable 10 TMHs. probable signal peptide; Conserved hypothetical protein. | Conserved hypothetical membrane protein. Homology to ebA4769 of Azoarcus sp. EbN1 of 53% (gnl|keqq|eba:ebA4769(KEGG)). Pfam: Cobalt transport protein. signal peptide. 3 TMHs; Family membership. | 0.435 |
| azo3063 | azo2371 | azo3063 | azo2371 | Conserved hypothetical membrane protein. Homology to CV2531 of C. violaceum of 37%. Tigrfam: 2A78: Carboxylate/Amino Acid/Amine Tranporter. Pfam: Integral membrane protein DUF6. probable 10 TMHs. probable signal peptide; Conserved hypothetical protein. | 30S ribosomal protein S4, truncated. Homology of aa 1 to 108 with rpsD of N. europaea of 67% (sprot|RS4B_NITEU(SRS)). With S5 and S12 plays an important role in translational accuracy (By similarity). Pfam: Ribosomal protein S4/S9 n-terminal domain. no signal peptide. no TMHs; Family membership; Belongs to the universal ribosomal protein uS4 family. | 0.455 |
| azo3063 | azo2910 | azo3063 | azo2910 | Conserved hypothetical membrane protein. Homology to CV2531 of C. violaceum of 37%. Tigrfam: 2A78: Carboxylate/Amino Acid/Amine Tranporter. Pfam: Integral membrane protein DUF6. probable 10 TMHs. probable signal peptide; Conserved hypothetical protein. | ATP-binding cassette (ABC) transporters form a large family of proteins responsible for translocation of a variety of compounds across biological membranes. They are composed of two transmembrane domains responsible for binding and transport and two nucleotide-binding domains responsible for coupling the energy of ATP hydrolysis to conformational changes in the TMDs, TREMBL:Q8FZX0 (58% identity); TREMBL:Q8U6Y9 (59% identity). InterPro (IPR003593): AAA ATPase. InterPro (IPR001687): ATP/GTP-binding site motif A (P-loop). InterPro (IPR003439): ABC transporter. Pfam (PF00005): ABC transpor [...] | 0.485 |
| azo3063 | brkB | azo3063 | azo3062 | Conserved hypothetical membrane protein. Homology to CV2531 of C. violaceum of 37%. Tigrfam: 2A78: Carboxylate/Amino Acid/Amine Tranporter. Pfam: Integral membrane protein DUF6. probable 10 TMHs. probable signal peptide; Conserved hypothetical protein. | Exoribonuclease II; Putative Ribonuclease RNASE_BN Protein, 28% identity to TrEMBL;Q8XPH6. Has PF03631, Ribonuclease BN-like family;IPR004664, RNase_BN: This family contains integral membrane proteins with 5 to 6 predicted transmembrane spans. The family include ribonuclease BN that is involved in tRNA maturation P32146. This family of proteins does not seem to contain any completely conserved polar residues that would be expected in a nuclease enzyme, suggesting that many members of this family may not have this catalytic activity; Conserved hypothetical protein. | 0.464 |
| azo3063 | cbiQ | azo3063 | azo2221 | Conserved hypothetical membrane protein. Homology to CV2531 of C. violaceum of 37%. Tigrfam: 2A78: Carboxylate/Amino Acid/Amine Tranporter. Pfam: Integral membrane protein DUF6. probable 10 TMHs. probable signal peptide; Conserved hypothetical protein. | Putative cobalt transport system permease protein; Part of the ABC transporter complex cbiKMQO involved in cobalt import. Similar to the cobalt transport membrane protein, CbiQ in A. pleuropneumoniae; Function unclear. | 0.435 |
| azo3063 | ispA | azo3063 | azo1199 | Conserved hypothetical membrane protein. Homology to CV2531 of C. violaceum of 37%. Tigrfam: 2A78: Carboxylate/Amino Acid/Amine Tranporter. Pfam: Integral membrane protein DUF6. probable 10 TMHs. probable signal peptide; Conserved hypothetical protein. | Geranyltranstransferase; Geranylgeranyl pyrophosphate synthetase chloroplast precursor (GGPP synthetase) (GGPS) [Includes: Dimethylallyltransferase (EC 2.5.1.1); Geranyltranstransferase (EC 2.5.1.10); Farnesyltranstransferase (EC 2.5.1.29)]. catalyzes the trans-addition of the three molecules of ipp onto dmapp to form geranylgeranyl pyrophosphate. InterPro: Polyprenyl synthetase; High confidence in function and specificity; Belongs to the FPP/GGPP synthase family. | 0.459 |
| azo3063 | ispB | azo3063 | azo1014 | Conserved hypothetical membrane protein. Homology to CV2531 of C. violaceum of 37%. Tigrfam: 2A78: Carboxylate/Amino Acid/Amine Tranporter. Pfam: Integral membrane protein DUF6. probable 10 TMHs. probable signal peptide; Conserved hypothetical protein. | Octaprenyl-diphosphate synthase; Polyprenyl synthetase,82% identity to TrEMBL;Q5P1Y1. Has Pfam;PF00348, Polyprenyl synthetase.(IPR000092,Polyprenyl_synt)A variety of isoprenoid compounds are synthesized by various organisms. For example in eukaryotes the isoprenoid biosynthetic pathway is responsible for the synthesis of a variety of end products including cholesterol, dolichol, ubiquinone or coenzyme Q. In bacteria this pathway leads to the synthesis of isopentenyl tRNA, isoprenoid quinones, and sugar carrier lipids. Among the enzymes that participate in that pathway, are a number of [...] | 0.459 |
| azo3063 | lrp1 | azo3063 | azo3064 | Conserved hypothetical membrane protein. Homology to CV2531 of C. violaceum of 37%. Tigrfam: 2A78: Carboxylate/Amino Acid/Amine Tranporter. Pfam: Integral membrane protein DUF6. probable 10 TMHs. probable signal peptide; Conserved hypothetical protein. | Leucine-responsive regulatory protein. Mediates a global response to leucine. Exogenous leucine affects the expression of a number of different opreons; Lrp mediates this effect for at least some of these operons. For example it is regulator of the branched-chain amino acid transport genes. Similar to SWISSPROT: sprot|LRP_ECOLI (40% Escherichia coli, leucine-responsive regulatory protein Lrp) InterPro: IPR000485 HTH_AsnC_lrp. Pfam: PF01037 AsnC family. HTH reporting nucleic acid binding motif; High confidence in function and specificity. | 0.461 |
| azo3063 | rpsD | azo3063 | azo3392 | Conserved hypothetical membrane protein. Homology to CV2531 of C. violaceum of 37%. Tigrfam: 2A78: Carboxylate/Amino Acid/Amine Tranporter. Pfam: Integral membrane protein DUF6. probable 10 TMHs. probable signal peptide; Conserved hypothetical protein. | 30S ribosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit. | 0.455 |
| azo3063 | uppS | azo3063 | azo1905 | Conserved hypothetical membrane protein. Homology to CV2531 of C. violaceum of 37%. Tigrfam: 2A78: Carboxylate/Amino Acid/Amine Tranporter. Pfam: Integral membrane protein DUF6. probable 10 TMHs. probable signal peptide; Conserved hypothetical protein. | Probable undecaprenyl pyrophosphate synthetase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids. | 0.603 |
| brkB | azo3063 | azo3062 | azo3063 | Exoribonuclease II; Putative Ribonuclease RNASE_BN Protein, 28% identity to TrEMBL;Q8XPH6. Has PF03631, Ribonuclease BN-like family;IPR004664, RNase_BN: This family contains integral membrane proteins with 5 to 6 predicted transmembrane spans. The family include ribonuclease BN that is involved in tRNA maturation P32146. This family of proteins does not seem to contain any completely conserved polar residues that would be expected in a nuclease enzyme, suggesting that many members of this family may not have this catalytic activity; Conserved hypothetical protein. | Conserved hypothetical membrane protein. Homology to CV2531 of C. violaceum of 37%. Tigrfam: 2A78: Carboxylate/Amino Acid/Amine Tranporter. Pfam: Integral membrane protein DUF6. probable 10 TMHs. probable signal peptide; Conserved hypothetical protein. | 0.464 |
| cbiQ | azo2910 | azo2221 | azo2910 | Putative cobalt transport system permease protein; Part of the ABC transporter complex cbiKMQO involved in cobalt import. Similar to the cobalt transport membrane protein, CbiQ in A. pleuropneumoniae; Function unclear. | ATP-binding cassette (ABC) transporters form a large family of proteins responsible for translocation of a variety of compounds across biological membranes. They are composed of two transmembrane domains responsible for binding and transport and two nucleotide-binding domains responsible for coupling the energy of ATP hydrolysis to conformational changes in the TMDs, TREMBL:Q8FZX0 (58% identity); TREMBL:Q8U6Y9 (59% identity). InterPro (IPR003593): AAA ATPase. InterPro (IPR001687): ATP/GTP-binding site motif A (P-loop). InterPro (IPR003439): ABC transporter. Pfam (PF00005): ABC transpor [...] | 0.827 |
| cbiQ | azo3063 | azo2221 | azo3063 | Putative cobalt transport system permease protein; Part of the ABC transporter complex cbiKMQO involved in cobalt import. Similar to the cobalt transport membrane protein, CbiQ in A. pleuropneumoniae; Function unclear. | Conserved hypothetical membrane protein. Homology to CV2531 of C. violaceum of 37%. Tigrfam: 2A78: Carboxylate/Amino Acid/Amine Tranporter. Pfam: Integral membrane protein DUF6. probable 10 TMHs. probable signal peptide; Conserved hypothetical protein. | 0.435 |
| ispA | azo3063 | azo1199 | azo3063 | Geranyltranstransferase; Geranylgeranyl pyrophosphate synthetase chloroplast precursor (GGPP synthetase) (GGPS) [Includes: Dimethylallyltransferase (EC 2.5.1.1); Geranyltranstransferase (EC 2.5.1.10); Farnesyltranstransferase (EC 2.5.1.29)]. catalyzes the trans-addition of the three molecules of ipp onto dmapp to form geranylgeranyl pyrophosphate. InterPro: Polyprenyl synthetase; High confidence in function and specificity; Belongs to the FPP/GGPP synthase family. | Conserved hypothetical membrane protein. Homology to CV2531 of C. violaceum of 37%. Tigrfam: 2A78: Carboxylate/Amino Acid/Amine Tranporter. Pfam: Integral membrane protein DUF6. probable 10 TMHs. probable signal peptide; Conserved hypothetical protein. | 0.459 |