| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| dnaB | dnaG | azo0722 | azo3226 | DnaB protein; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. | 0.994 |
| dnaB | metG | azo0722 | azo3203 | DnaB protein; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. | MetG protein; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | 0.541 |
| dnaB | priA | azo0722 | azo3978 | DnaB protein; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. | Primosomal protein N' (Replication factor Y); Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. | 0.918 |
| dnaB | recQ | azo0722 | azo3318 | DnaB protein; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. | ATP-dependent DNA helicase recQ (EC 3.6.1.-). INVOLVED IN THE RECF RECOMBINATION PATHWAY; ITS GENE EXPRESSION IS UNDER THE REGULATION OF THE SOS SYSTEM. IT IS A DNA HELICASE. recq: ATP-dependent DNA helicase RecQ; High confidence in function and specificity. | 0.920 |
| dnaB | ruvA | azo0722 | azo0602 | DnaB protein; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. | Holliday junction DNA helicase; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. | 0.849 |
| dnaB | ruvB | azo0722 | azo0601 | DnaB protein; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. | Holliday junction DNA helicase; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. | 0.626 |
| dnaB | ruvC | azo0722 | azo0571 | DnaB protein; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. | Crossover junction endodeoxyribonuclease; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. | 0.413 |
| dnaB | ycjD | azo0722 | azo3067 | DnaB protein; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. | Hypothetical protein ycjD,50% identity(65% similarity) to SwissProt;P45736. Has PF04480, Protein of unknown function (DUF559);IPR007569; No SIgnal Peptide or TMH present. vsr: DNA mismatch endonuclease (vsr). | 0.741 |
| dnaG | dnaB | azo3226 | azo0722 | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. | DnaB protein; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. | 0.994 |
| dnaG | metG | azo3226 | azo3203 | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. | MetG protein; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | 0.557 |
| dnaG | priA | azo3226 | azo3978 | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. | Primosomal protein N' (Replication factor Y); Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. | 0.902 |
| dnaG | recQ | azo3226 | azo3318 | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. | ATP-dependent DNA helicase recQ (EC 3.6.1.-). INVOLVED IN THE RECF RECOMBINATION PATHWAY; ITS GENE EXPRESSION IS UNDER THE REGULATION OF THE SOS SYSTEM. IT IS A DNA HELICASE. recq: ATP-dependent DNA helicase RecQ; High confidence in function and specificity. | 0.905 |
| dnaG | ruvA | azo3226 | azo0602 | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. | Holliday junction DNA helicase; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. | 0.674 |
| dnaG | ruvB | azo3226 | azo0601 | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. | Holliday junction DNA helicase; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. | 0.738 |
| dnaG | ruvC | azo3226 | azo0571 | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. | Crossover junction endodeoxyribonuclease; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. | 0.426 |
| dnaG | uvrB | azo3226 | azo1611 | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. | Excinuclease ABC subunit B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...] | 0.402 |
| dnaG | ycjD | azo3226 | azo3067 | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. | Hypothetical protein ycjD,50% identity(65% similarity) to SwissProt;P45736. Has PF04480, Protein of unknown function (DUF559);IPR007569; No SIgnal Peptide or TMH present. vsr: DNA mismatch endonuclease (vsr). | 0.758 |
| hisA | metG | azo3345 | azo3203 | Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase, HisA. Similar to sprot|HIS4_RALSO (76%) and to sprot|HIS4_AZOBR (52%). Proteins involved in steps 4 and 6 of the histidine biosynthesis pathway are contained in one family. These enzymes are called His6 and His7 in eukaryotes and HisA and HisF in prokaryotes. HisA is a phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase, involved in the fourth step of histidine biosynthesis. TIGRFAM (TIGR00007): phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase Pfam: Histidine biosynthesis [...] | MetG protein; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | 0.510 |
| hisA | ycjD | azo3345 | azo3067 | Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase, HisA. Similar to sprot|HIS4_RALSO (76%) and to sprot|HIS4_AZOBR (52%). Proteins involved in steps 4 and 6 of the histidine biosynthesis pathway are contained in one family. These enzymes are called His6 and His7 in eukaryotes and HisA and HisF in prokaryotes. HisA is a phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase, involved in the fourth step of histidine biosynthesis. TIGRFAM (TIGR00007): phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase Pfam: Histidine biosynthesis [...] | Hypothetical protein ycjD,50% identity(65% similarity) to SwissProt;P45736. Has PF04480, Protein of unknown function (DUF559);IPR007569; No SIgnal Peptide or TMH present. vsr: DNA mismatch endonuclease (vsr). | 0.739 |
| metG | dnaB | azo3203 | azo0722 | MetG protein; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | DnaB protein; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. | 0.541 |
