Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
trkH1Membrane component of the potassium uptake system. 38% Cat_transpt. IPR004772; K_transptTrk. Pfam: PF02386; TrkH; 1. SignalP.present. TMHelix:9; High confidence in function and specificity. (442 aa)    
Predicted Functional Partners:
trkA1
Potassium uptake protein. Part of the constitutive potassium transport systems trkG and trkH. May regulate the transport activity of trkG and trkH systems. Binds to NAD+ and NADH.Peripherally bound to the inner side of the inner membrane via the trkG and trkH proteins. 41% NAD_BS. IPR006037; TrkAC. IPR003148; TrkA_N. Pfam:PF02080; TrkA_C; 1. PF02254; TrkA_N; 1. Pfam:KTN: NAD-binding domain; Specificity unclear.
 
 
 0.987
azo1529
NAD-binding domain of the Kef-type K+ transport system fused to a uncharacterized conserved domain; 42% K+channel_pore.IPR003148; TrkA_N. Pfam:PF02254; TrkA_N; 2. TMhelix:3; Function unclear.
  
 
 0.760
trkA2
Potassium uptake protein TrkA. Part of the constitutive potassium transport systems trkG and trkH. May regulate the transport activity of trkG and trkH systems. Binds to NAD+ and NADH.Peripherally bound to the inner side of the inner membrane via the trkG and trkH proteins. 51% NAD_BS.IPR006036; TrkA_Kuptake.IPR003148; TrkA_N. IPR006037; TrkAC. Pfam:PF02080; TrkA-C; 2.PF02254; TrkA-N; 2; High confidence in function and specificity.
  
 
 0.760
kdpD2
Probable sensor for high-affinity potassium transport system,; High confidence in function and specificity.
     
 0.607
azo3093
Two component system transcriptional regulatory protein, 53% Identity to TrEMBL;Q7W532,Q8XUU6. Has SMART;SM00448,REC, cheY-homologous receiver domain;IPR001789;CheY regulates the clockwise rotation of E. coli flagellar motors. This domain contains a phosphoacceptor site that is phosphorylated by histidine kinase homologues. Has OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription] Has PF00486, Transcriptional regulatory protein, C terminal;IPR001867 Trans_reg_C; This domain is almost al [...]
     
 0.600
azo0795
Probable glutathione-regulated potassium-efflux system protein (K(+)/H(+) antiporter). Transport system that facilitate potassium-efflux possibly by potassium-proton antiport. 50% Na_H_porter.IPR006037; TrkAC.IPR003148; TrkA_N. Pfam: PF00999; Na_H_Exchanger; 1.PF02080; TrkA_C; 1.PF02254; TrkA_N; 1. TMhelix: 11; High confidence in function and specificity; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.
   
 
 0.488
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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