Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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[Homology]
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azo3137Conserved hypothetical membrane protein. This is a family of hypothetical proteins. A number of the sequence records state they are transmembrane proteins or putative permeases.It is not clear what source suggested that these proteins might be permeases and this information should be treated with caution. TREMBL:Q82Y01: 39% identity; 58% similarity. TREMBL:Q8XW51: 37% identity; 53% similarity. InterPro:IPR002549 Pfam: PF01594:Protein of unknown function DUF70 Signal P predicted signal peptide and TMHMM predicted transmembrane helices; Conserved hypothetical protein. (372 aa)    
Predicted Functional Partners:
azo3138
Putative chromosomal replication initiator protein; Region start changed from 3447165 to 3447246 (-81 bases); Belongs to the DnaA family.
 
   
 0.816
atpE
Probable ATP synthase C chain; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
     
  0.684
azo3139
Haloacid dehalogenase-like hydrolase family is structurally different from the alpha/beta hydrolase family (abhydrolase). This family includes L-2-haloacid dehalogenase, epoxide hydrolases and phosphatases. Similar to trembl|Q82XZ3 (63%) and to pir|B83604 (47%). Pfam (PF00702): haloacid dehalogenase-like hydrolase; Family membership.
       0.675
purC
Phosphoribosylaminoimidazolesuccinocarboxamide synthase (Phosphoribosylaminoimidazole-succinocarboxamide synthase) (SAICAR synthase); High confidence in function and specificity; Belongs to the SAICAR synthetase family.
      0.635
purM
Phosphoribosylformylglycinamidine cyclo-ligase (Phosphoribosyl-aminoimidazole synthetase) (Phosphoribosylaminoimidazole synthetase) (AIR synthase) (AIR synthetase) (AIRS) InterPro: Phosphoribosylformylglycinamidine cyclo-ligase; High confidence in function and specificity.
       0.515
pcnB
Probable poly(A) polymerase; Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control. Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.
       0.497
folK
2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase (7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase) (HPPK) (6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase) (PPPK). InterPro: 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase Pfam:7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase; High confidence in function and specificity.
       0.497
azo3142
Conserved hypothetical membrane protein. Homology to PA1577 of Pseudomonas aeruginosa of 69% (trembl|Q9I3E0). Has PF04342, IPR007437;Protein of unknown function, DUF486;This family contains several proteins of uncharacterised function. No signal peptide. 4 TMHs; Conserved hypothetical protein.
       0.496
azo3143
Deoxyguanosine kinase, probable (2.7.1.113) InterPro: Thymidylate kinase DTMP_kinase: thymidylate kinase; Family membership.
       0.496
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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