| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| azo3171 | azo3172 | azo3171 | azo3172 | Conserved hypothetical protein. Homology to ne2236 of N. europaea of 58% (trembl:Q82SS1). No domains predicted. No signal peptide. No TMHs. | Putative long chain fatty acid coA ligase; It belongs to the ATP-dependent AMP-binding enzyme family. Entry name Q9X7Y5 Primary accession number Q9X7Y5 Identities = 193/609 (31%) InterPro IPR000873; AMP-bind. Pfam PF00501; AMP-binding; 2 Signal peptide probability: 0.006 Number of predicted TMHs: 0; Family membership. | 0.784 |
| azo3171 | azo3189 | azo3171 | azo3189 | Conserved hypothetical protein. Homology to ne2236 of N. europaea of 58% (trembl:Q82SS1). No domains predicted. No signal peptide. No TMHs. | NDPsugar dehydrogenase; CapL protein. Required for the biosynthesis of type 1 capsular polysaccharide. InterPro: UDP-glucose/GDP-mannose dehydrogenase family gutA: pts system glucitol/sorbitol-s; Specificity unclear. | 0.688 |
| azo3171 | coxC | azo3171 | azo3299 | Conserved hypothetical protein. Homology to ne2236 of N. europaea of 58% (trembl:Q82SS1). No domains predicted. No signal peptide. No TMHs. | Cytochrome c oxidase polypeptide III Subunits I II and III form the functional core of the enzyme complex. InterPro: Cytochrome c oxidase subunit III; High confidence in function and specificity. | 0.677 |
| azo3171 | cyaY | azo3171 | azo3652 | Conserved hypothetical protein. Homology to ne2236 of N. europaea of 58% (trembl:Q82SS1). No domains predicted. No signal peptide. No TMHs. | Putative CyaY protein; Involved in iron-sulfur (Fe-S) cluster assembly. May act as a regulator of Fe-S biogenesis. | 0.680 |
| azo3171 | galE1 | azo3171 | azo3173 | Conserved hypothetical protein. Homology to ne2236 of N. europaea of 58% (trembl:Q82SS1). No domains predicted. No signal peptide. No TMHs. | UDP-glucose 4-epimerase (EC 5.1.3.2) (Galactowaldenase) (UDP- galactose 4-epimerase). PLAYS AN ESSENTIAL ROLE IN THE INCORPORATION OF GALACTOSE INTO MENINGOCOCCAL LIPOPOLYSACCHARIDE SURFACE MOLECULES WHICH ARE IMPORTANT FOR PATHOGENESIS. hemL: glutamate-1-semialdehyde-21-amin; High confidence in function and specificity. | 0.859 |
| azo3171 | gltB | azo3171 | azo3642 | Conserved hypothetical protein. Homology to ne2236 of N. europaea of 58% (trembl:Q82SS1). No domains predicted. No signal peptide. No TMHs. | Ferredoxin-dependent glutamate synthase,; Specificity unclear. | 0.881 |
| azo3171 | guaA | azo3171 | azo1581 | Conserved hypothetical protein. Homology to ne2236 of N. europaea of 58% (trembl:Q82SS1). No domains predicted. No signal peptide. No TMHs. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.735 |
| azo3171 | mnaA | azo3171 | azo3278 | Conserved hypothetical protein. Homology to ne2236 of N. europaea of 58% (trembl:Q82SS1). No domains predicted. No signal peptide. No TMHs. | UDP-N-acetylglucosamine 2-epimerase (EC 5.1.3.14) (UDP-GlcNAc-2- epimerase). Catalyzes the reversible epimerization at C-2 of UDP-N- acetylglucosamine (UDP-GlcNAc) and thereby provides bacteria with UDP-N-acetylmannosamine (UDP-ManNAc) the activated donor of ManNAc residues (By similarity). InterPro: UDP-N-acetylglucosamine 2-epimerase; High confidence in function and specificity. | 0.891 |
| azo3171 | moaE | azo3171 | azo1564 | Conserved hypothetical protein. Homology to ne2236 of N. europaea of 58% (trembl:Q82SS1). No domains predicted. No signal peptide. No TMHs. | Molybdenum cofactor biosynthesis protein E; Molybdopterin converting factor subunit 2 (MPT synthase subunit 2) (Molybdopterin synthase subunit 2). Converts molybdopterin precursor Z into molybdopterin. This requires the incorporation of two sulfur atoms into precursor Z to generate a dithiolene group; High confidence in function and specificity. | 0.693 |
| azo3171 | nifS | azo3171 | azo0552 | Conserved hypothetical protein. Homology to ne2236 of N. europaea of 58% (trembl:Q82SS1). No domains predicted. No signal peptide. No TMHs. | Cysteine desulphurase; Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. | 0.714 |
| azo3172 | azo3171 | azo3172 | azo3171 | Putative long chain fatty acid coA ligase; It belongs to the ATP-dependent AMP-binding enzyme family. Entry name Q9X7Y5 Primary accession number Q9X7Y5 Identities = 193/609 (31%) InterPro IPR000873; AMP-bind. Pfam PF00501; AMP-binding; 2 Signal peptide probability: 0.006 Number of predicted TMHs: 0; Family membership. | Conserved hypothetical protein. Homology to ne2236 of N. europaea of 58% (trembl:Q82SS1). No domains predicted. No signal peptide. No TMHs. | 0.784 |
| azo3172 | galE1 | azo3172 | azo3173 | Putative long chain fatty acid coA ligase; It belongs to the ATP-dependent AMP-binding enzyme family. Entry name Q9X7Y5 Primary accession number Q9X7Y5 Identities = 193/609 (31%) InterPro IPR000873; AMP-bind. Pfam PF00501; AMP-binding; 2 Signal peptide probability: 0.006 Number of predicted TMHs: 0; Family membership. | UDP-glucose 4-epimerase (EC 5.1.3.2) (Galactowaldenase) (UDP- galactose 4-epimerase). PLAYS AN ESSENTIAL ROLE IN THE INCORPORATION OF GALACTOSE INTO MENINGOCOCCAL LIPOPOLYSACCHARIDE SURFACE MOLECULES WHICH ARE IMPORTANT FOR PATHOGENESIS. hemL: glutamate-1-semialdehyde-21-amin; High confidence in function and specificity. | 0.924 |
| azo3189 | azo3171 | azo3189 | azo3171 | NDPsugar dehydrogenase; CapL protein. Required for the biosynthesis of type 1 capsular polysaccharide. InterPro: UDP-glucose/GDP-mannose dehydrogenase family gutA: pts system glucitol/sorbitol-s; Specificity unclear. | Conserved hypothetical protein. Homology to ne2236 of N. europaea of 58% (trembl:Q82SS1). No domains predicted. No signal peptide. No TMHs. | 0.688 |
| azo3189 | mnaA | azo3189 | azo3278 | NDPsugar dehydrogenase; CapL protein. Required for the biosynthesis of type 1 capsular polysaccharide. InterPro: UDP-glucose/GDP-mannose dehydrogenase family gutA: pts system glucitol/sorbitol-s; Specificity unclear. | UDP-N-acetylglucosamine 2-epimerase (EC 5.1.3.14) (UDP-GlcNAc-2- epimerase). Catalyzes the reversible epimerization at C-2 of UDP-N- acetylglucosamine (UDP-GlcNAc) and thereby provides bacteria with UDP-N-acetylmannosamine (UDP-ManNAc) the activated donor of ManNAc residues (By similarity). InterPro: UDP-N-acetylglucosamine 2-epimerase; High confidence in function and specificity. | 0.993 |
| coxC | azo3171 | azo3299 | azo3171 | Cytochrome c oxidase polypeptide III Subunits I II and III form the functional core of the enzyme complex. InterPro: Cytochrome c oxidase subunit III; High confidence in function and specificity. | Conserved hypothetical protein. Homology to ne2236 of N. europaea of 58% (trembl:Q82SS1). No domains predicted. No signal peptide. No TMHs. | 0.677 |
| cyaY | azo3171 | azo3652 | azo3171 | Putative CyaY protein; Involved in iron-sulfur (Fe-S) cluster assembly. May act as a regulator of Fe-S biogenesis. | Conserved hypothetical protein. Homology to ne2236 of N. europaea of 58% (trembl:Q82SS1). No domains predicted. No signal peptide. No TMHs. | 0.680 |
| cyaY | moaE | azo3652 | azo1564 | Putative CyaY protein; Involved in iron-sulfur (Fe-S) cluster assembly. May act as a regulator of Fe-S biogenesis. | Molybdenum cofactor biosynthesis protein E; Molybdopterin converting factor subunit 2 (MPT synthase subunit 2) (Molybdopterin synthase subunit 2). Converts molybdopterin precursor Z into molybdopterin. This requires the incorporation of two sulfur atoms into precursor Z to generate a dithiolene group; High confidence in function and specificity. | 0.745 |
| cyaY | nifS | azo3652 | azo0552 | Putative CyaY protein; Involved in iron-sulfur (Fe-S) cluster assembly. May act as a regulator of Fe-S biogenesis. | Cysteine desulphurase; Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. | 0.920 |
| galE1 | azo3171 | azo3173 | azo3171 | UDP-glucose 4-epimerase (EC 5.1.3.2) (Galactowaldenase) (UDP- galactose 4-epimerase). PLAYS AN ESSENTIAL ROLE IN THE INCORPORATION OF GALACTOSE INTO MENINGOCOCCAL LIPOPOLYSACCHARIDE SURFACE MOLECULES WHICH ARE IMPORTANT FOR PATHOGENESIS. hemL: glutamate-1-semialdehyde-21-amin; High confidence in function and specificity. | Conserved hypothetical protein. Homology to ne2236 of N. europaea of 58% (trembl:Q82SS1). No domains predicted. No signal peptide. No TMHs. | 0.859 |
| galE1 | azo3172 | azo3173 | azo3172 | UDP-glucose 4-epimerase (EC 5.1.3.2) (Galactowaldenase) (UDP- galactose 4-epimerase). PLAYS AN ESSENTIAL ROLE IN THE INCORPORATION OF GALACTOSE INTO MENINGOCOCCAL LIPOPOLYSACCHARIDE SURFACE MOLECULES WHICH ARE IMPORTANT FOR PATHOGENESIS. hemL: glutamate-1-semialdehyde-21-amin; High confidence in function and specificity. | Putative long chain fatty acid coA ligase; It belongs to the ATP-dependent AMP-binding enzyme family. Entry name Q9X7Y5 Primary accession number Q9X7Y5 Identities = 193/609 (31%) InterPro IPR000873; AMP-bind. Pfam PF00501; AMP-binding; 2 Signal peptide probability: 0.006 Number of predicted TMHs: 0; Family membership. | 0.924 |