| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| azo1488 | azo3171 | azo1488 | azo3171 | Conserved hypothetical protein. Homology to Daro03003756 of Dechloromonas aromatica of 53% (gi|41722684|ref|ZP_00149673.1|(NBCI ENTREZ)). No domains predicted. No signal peptide. No TMHs. | Conserved hypothetical protein. Homology to ne2236 of N. europaea of 58% (trembl:Q82SS1). No domains predicted. No signal peptide. No TMHs. | 0.549 |
| azo2350 | azo3171 | azo2350 | azo3171 | Conserved hypothetical protein. Homology to orf of Desulfovibrio vulgaris of 41% (tremblnew|AAS97780(SRS)). No domain predicted. No TMHs. No signal peptide. | Conserved hypothetical protein. Homology to ne2236 of N. europaea of 58% (trembl:Q82SS1). No domains predicted. No signal peptide. No TMHs. | 0.568 |
| azo3171 | azo1488 | azo3171 | azo1488 | Conserved hypothetical protein. Homology to ne2236 of N. europaea of 58% (trembl:Q82SS1). No domains predicted. No signal peptide. No TMHs. | Conserved hypothetical protein. Homology to Daro03003756 of Dechloromonas aromatica of 53% (gi|41722684|ref|ZP_00149673.1|(NBCI ENTREZ)). No domains predicted. No signal peptide. No TMHs. | 0.549 |
| azo3171 | azo2350 | azo3171 | azo2350 | Conserved hypothetical protein. Homology to ne2236 of N. europaea of 58% (trembl:Q82SS1). No domains predicted. No signal peptide. No TMHs. | Conserved hypothetical protein. Homology to orf of Desulfovibrio vulgaris of 41% (tremblnew|AAS97780(SRS)). No domain predicted. No TMHs. No signal peptide. | 0.568 |
| azo3171 | azo3172 | azo3171 | azo3172 | Conserved hypothetical protein. Homology to ne2236 of N. europaea of 58% (trembl:Q82SS1). No domains predicted. No signal peptide. No TMHs. | Putative long chain fatty acid coA ligase; It belongs to the ATP-dependent AMP-binding enzyme family. Entry name Q9X7Y5 Primary accession number Q9X7Y5 Identities = 193/609 (31%) InterPro IPR000873; AMP-bind. Pfam PF00501; AMP-binding; 2 Signal peptide probability: 0.006 Number of predicted TMHs: 0; Family membership. | 0.785 |
| azo3171 | azo3189 | azo3171 | azo3189 | Conserved hypothetical protein. Homology to ne2236 of N. europaea of 58% (trembl:Q82SS1). No domains predicted. No signal peptide. No TMHs. | NDPsugar dehydrogenase; CapL protein. Required for the biosynthesis of type 1 capsular polysaccharide. InterPro: UDP-glucose/GDP-mannose dehydrogenase family gutA: pts system glucitol/sorbitol-s; Specificity unclear. | 0.654 |
| azo3171 | galE1 | azo3171 | azo3173 | Conserved hypothetical protein. Homology to ne2236 of N. europaea of 58% (trembl:Q82SS1). No domains predicted. No signal peptide. No TMHs. | UDP-glucose 4-epimerase (EC 5.1.3.2) (Galactowaldenase) (UDP- galactose 4-epimerase). PLAYS AN ESSENTIAL ROLE IN THE INCORPORATION OF GALACTOSE INTO MENINGOCOCCAL LIPOPOLYSACCHARIDE SURFACE MOLECULES WHICH ARE IMPORTANT FOR PATHOGENESIS. hemL: glutamate-1-semialdehyde-21-amin; High confidence in function and specificity. | 0.860 |
| azo3171 | gltB | azo3171 | azo3642 | Conserved hypothetical protein. Homology to ne2236 of N. europaea of 58% (trembl:Q82SS1). No domains predicted. No signal peptide. No TMHs. | Ferredoxin-dependent glutamate synthase,; Specificity unclear. | 0.869 |
| azo3171 | guaA | azo3171 | azo1581 | Conserved hypothetical protein. Homology to ne2236 of N. europaea of 58% (trembl:Q82SS1). No domains predicted. No signal peptide. No TMHs. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.791 |
| azo3171 | mnaA | azo3171 | azo3278 | Conserved hypothetical protein. Homology to ne2236 of N. europaea of 58% (trembl:Q82SS1). No domains predicted. No signal peptide. No TMHs. | UDP-N-acetylglucosamine 2-epimerase (EC 5.1.3.14) (UDP-GlcNAc-2- epimerase). Catalyzes the reversible epimerization at C-2 of UDP-N- acetylglucosamine (UDP-GlcNAc) and thereby provides bacteria with UDP-N-acetylmannosamine (UDP-ManNAc) the activated donor of ManNAc residues (By similarity). InterPro: UDP-N-acetylglucosamine 2-epimerase; High confidence in function and specificity. | 0.925 |
| azo3171 | thiS | azo3171 | azo3970 | Conserved hypothetical protein. Homology to ne2236 of N. europaea of 58% (trembl:Q82SS1). No domains predicted. No signal peptide. No TMHs. | Thiamine biosynthesis protein ThiS; Putative sulfur transfer protein involved in thimanin biosynsthesis; High confidence in function and specificity. | 0.807 |
| azo3171 | xanB | azo3171 | azo2085 | Conserved hypothetical protein. Homology to ne2236 of N. europaea of 58% (trembl:Q82SS1). No domains predicted. No signal peptide. No TMHs. | Probable xanthan biosynthesis protein XanB. Homology to xanB of X. campestris of 60% (sprot|XANB_XANCP(SRS)) Xanthan biosynthesis protein XanB is a multifunctional enzyme including Mannose-6-phosphate isomerase (EC 5.3.1.8) (Phosphomannose isomerase) (PMI) (Phosphohexomutase)and Mannose-1-phosphate guanylyl transferase (GDP) (EC 2.7.7.22) (GDP-mannose pyrophosphorylase) (GMP). InterPro: ADP-glucose pyrophosphorylase (IPR005835); Mannose-6-phosphate isomerase type II (IPR001538) Pfam: Nucleotidyl transferase, Mannose-6-phosphate isomerase no signal peptide no TMHs; Family membership. | 0.621 |
| azo3172 | azo3171 | azo3172 | azo3171 | Putative long chain fatty acid coA ligase; It belongs to the ATP-dependent AMP-binding enzyme family. Entry name Q9X7Y5 Primary accession number Q9X7Y5 Identities = 193/609 (31%) InterPro IPR000873; AMP-bind. Pfam PF00501; AMP-binding; 2 Signal peptide probability: 0.006 Number of predicted TMHs: 0; Family membership. | Conserved hypothetical protein. Homology to ne2236 of N. europaea of 58% (trembl:Q82SS1). No domains predicted. No signal peptide. No TMHs. | 0.785 |
| azo3172 | galE1 | azo3172 | azo3173 | Putative long chain fatty acid coA ligase; It belongs to the ATP-dependent AMP-binding enzyme family. Entry name Q9X7Y5 Primary accession number Q9X7Y5 Identities = 193/609 (31%) InterPro IPR000873; AMP-bind. Pfam PF00501; AMP-binding; 2 Signal peptide probability: 0.006 Number of predicted TMHs: 0; Family membership. | UDP-glucose 4-epimerase (EC 5.1.3.2) (Galactowaldenase) (UDP- galactose 4-epimerase). PLAYS AN ESSENTIAL ROLE IN THE INCORPORATION OF GALACTOSE INTO MENINGOCOCCAL LIPOPOLYSACCHARIDE SURFACE MOLECULES WHICH ARE IMPORTANT FOR PATHOGENESIS. hemL: glutamate-1-semialdehyde-21-amin; High confidence in function and specificity. | 0.927 |
| azo3189 | azo3171 | azo3189 | azo3171 | NDPsugar dehydrogenase; CapL protein. Required for the biosynthesis of type 1 capsular polysaccharide. InterPro: UDP-glucose/GDP-mannose dehydrogenase family gutA: pts system glucitol/sorbitol-s; Specificity unclear. | Conserved hypothetical protein. Homology to ne2236 of N. europaea of 58% (trembl:Q82SS1). No domains predicted. No signal peptide. No TMHs. | 0.654 |
| azo3189 | mnaA | azo3189 | azo3278 | NDPsugar dehydrogenase; CapL protein. Required for the biosynthesis of type 1 capsular polysaccharide. InterPro: UDP-glucose/GDP-mannose dehydrogenase family gutA: pts system glucitol/sorbitol-s; Specificity unclear. | UDP-N-acetylglucosamine 2-epimerase (EC 5.1.3.14) (UDP-GlcNAc-2- epimerase). Catalyzes the reversible epimerization at C-2 of UDP-N- acetylglucosamine (UDP-GlcNAc) and thereby provides bacteria with UDP-N-acetylmannosamine (UDP-ManNAc) the activated donor of ManNAc residues (By similarity). InterPro: UDP-N-acetylglucosamine 2-epimerase; High confidence in function and specificity. | 0.994 |
| azo3189 | xanB | azo3189 | azo2085 | NDPsugar dehydrogenase; CapL protein. Required for the biosynthesis of type 1 capsular polysaccharide. InterPro: UDP-glucose/GDP-mannose dehydrogenase family gutA: pts system glucitol/sorbitol-s; Specificity unclear. | Probable xanthan biosynthesis protein XanB. Homology to xanB of X. campestris of 60% (sprot|XANB_XANCP(SRS)) Xanthan biosynthesis protein XanB is a multifunctional enzyme including Mannose-6-phosphate isomerase (EC 5.3.1.8) (Phosphomannose isomerase) (PMI) (Phosphohexomutase)and Mannose-1-phosphate guanylyl transferase (GDP) (EC 2.7.7.22) (GDP-mannose pyrophosphorylase) (GMP). InterPro: ADP-glucose pyrophosphorylase (IPR005835); Mannose-6-phosphate isomerase type II (IPR001538) Pfam: Nucleotidyl transferase, Mannose-6-phosphate isomerase no signal peptide no TMHs; Family membership. | 0.556 |
| galE1 | azo3171 | azo3173 | azo3171 | UDP-glucose 4-epimerase (EC 5.1.3.2) (Galactowaldenase) (UDP- galactose 4-epimerase). PLAYS AN ESSENTIAL ROLE IN THE INCORPORATION OF GALACTOSE INTO MENINGOCOCCAL LIPOPOLYSACCHARIDE SURFACE MOLECULES WHICH ARE IMPORTANT FOR PATHOGENESIS. hemL: glutamate-1-semialdehyde-21-amin; High confidence in function and specificity. | Conserved hypothetical protein. Homology to ne2236 of N. europaea of 58% (trembl:Q82SS1). No domains predicted. No signal peptide. No TMHs. | 0.860 |
| galE1 | azo3172 | azo3173 | azo3172 | UDP-glucose 4-epimerase (EC 5.1.3.2) (Galactowaldenase) (UDP- galactose 4-epimerase). PLAYS AN ESSENTIAL ROLE IN THE INCORPORATION OF GALACTOSE INTO MENINGOCOCCAL LIPOPOLYSACCHARIDE SURFACE MOLECULES WHICH ARE IMPORTANT FOR PATHOGENESIS. hemL: glutamate-1-semialdehyde-21-amin; High confidence in function and specificity. | Putative long chain fatty acid coA ligase; It belongs to the ATP-dependent AMP-binding enzyme family. Entry name Q9X7Y5 Primary accession number Q9X7Y5 Identities = 193/609 (31%) InterPro IPR000873; AMP-bind. Pfam PF00501; AMP-binding; 2 Signal peptide probability: 0.006 Number of predicted TMHs: 0; Family membership. | 0.927 |
| gltB | azo3171 | azo3642 | azo3171 | Ferredoxin-dependent glutamate synthase,; Specificity unclear. | Conserved hypothetical protein. Homology to ne2236 of N. europaea of 58% (trembl:Q82SS1). No domains predicted. No signal peptide. No TMHs. | 0.869 |