Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
azo3187Conserved hypothetical serine protease. Homology to mucD of N. europaea of 50% (trembl|Q82XA8). InterPro: Serine proteases trypsin family (IPR001254); Chymotrypsin serin protease family (S1) (IPR001314). Pfam: Trypsin. signal peptide. no TMHs; Family membership. (264 aa)    
Predicted Functional Partners:
azo3190
Conserved hypothetical protein; In part; Function unclear.
 
  
 0.919
azo3192
Putative two component sensor histidine kinase,; Family membership.
 
    0.916
azo3188
Soluble lytic murein transglycosylase precursor (EC 3.2.1.-) (Slt70). Murein-degrading enzyme. Catalyzes the cleavage of the glycosidic bonds between N-acetylmuramic acid and N- acetylglucosamine residues in peptidoglycan. May play a role in recycling of muropeptides during cell elongation and/or cell division (By similarity). InterPro: SLT domain; Family membership.
   
 0.856
glpK
Probable glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family.
   
 0.828
atoC
Probable acetoacetate metabolism regulatory protein,; Specificity unclear.
 
     0.758
azo3189
NDPsugar dehydrogenase; CapL protein. Required for the biosynthesis of type 1 capsular polysaccharide. InterPro: UDP-glucose/GDP-mannose dehydrogenase family gutA: pts system glucitol/sorbitol-s; Specificity unclear.
       0.754
azo0985
Conserved hypothetical protein, 35% identity (56% similarity) to TrEMBL;Q82U70. Signal peptide Present. No TMH reported Present.
 
     0.753
azo3274
Glycosyltransferase; InterPro: Glycosyl transferases group 1; Specificity unclear.
  
    0.750
azo3267
Conserved hypothetical membrane protein. Homology to RferDRAFT_3275 of Rhodoferax ferrireducens of 46%. Pfam: O-Antigen Polymerase. This group of bacterial proteins is involved in the synthesis of O-antigen, a lipopolysaccharide found in the outer membrane in gram-negative bacteria. The enzyme is coded for by the gene wzy which is part of the O-antigen gene cluster. No signal peptide. 9 TMHs; Family membership.
  
     0.748
azo3282
Conserved hypothetical polysaccharide chain length determinant protein. Homology to ebA4249 of Azoarcus sp. EbN1 of 66%. No signal peptide. 3 TMHS. Pfam: Wzz = Chain length determinant protein. This family includes proteins involved in lipopolysaccharide (lps) biosynthesis. This family comprises the whole length of chain length determinant protein (or wzz protein) that confers a modal distribution of chain length on the O-antigen component of lps. This region is also found as part of bacterial tyrosine kinases such as ETK_ECOLI; Family membership.
  
     0.744
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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