STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
adiAPutative orn/arg/lys decarboxylase. Homology to adiA of E. coli of 37% (sprot|ADIA_ECOLI). This family is composed of ornithine decarboxylases (ODC), arginine decarboxylases (ADC) and lysine decarboxylases (LDC), and belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase domain superfamily (fold I). These enzymes catalyse the decarboxylation of ornithine,arginine, or lysine, respectively using PLP as a co-factor. Pfam: Orn/Lys/Arg decarboxylase no signal peptide no TMHs; Specificity unclear. (747 aa)    
Predicted Functional Partners:
argH
ArgH protein; Argininosuccinate lyase (EC 4.3.2.1) (Arginosuccinase) (ASAL); High confidence in function and specificity.
     
 0.935
moxR1
MoxR protein (MxaR protein). MAY BE INVOLVED IN THE REGULATION OF FORMATION OF ACTIVE METHANOL DEHYDROGENASE. TREMBL:Q883V0: 60% identity, 73% similarity SMART: SM00382; AAA InterPro: IPR003593; AAA_ATPase. IPR001270; Chaprnin_clpA/B. IPR003442; UPF0079. Pfam: PF02367; UPF0079; Pfam: Mg_chelatase:Magnesium chelatase, subunit ChlI ruvB: Holliday junction DNA helicase Ru No signal peptide and transmembrane helices; High confidence in function and specificity.
    
 
 0.806
moxR2
MoxR protein, putative; MoxR protein (MxaR protein). MAY BE INVOLVED IN THE REGULATION OF FORMATION OF ACTIVE METHANOL DEHYDROGENASE. TREMBLnew:CAE55395: 54% identity, 71% similarity InterPro:IPR003593; AAA_ATPase. IPR000523; Mg_chelatse_chII. Pfam PF01078; Mg_chelatase; 1. SMART SM00382; AAA; 1 InterPro IPR003593; AAA_ATPas ruvB: Holliday junction DNA helicase Ru; High confidence in function and specificity.
    
 
 0.806
azo0085
Conserved hypothetical protein. Homology to RS04117 of R.solanacearum of 52% (tremble:Q8Y0H4) No domains predicted. No signal peptide. No TMHs.
  
     0.682
argA
Amino-acid N-acetyltransferases acting mainly on glutamate in the first step of the 'acetylated' ornithine biosynthesis pathway. For this reason it is also called N-acetylglutamate synthase. The enzyme may also act on aspartate. Similar to sprot|ARGA_YERPE (44%) and to sprot|ARGA_ECOLI (43%). Pfam (PF00696): Aspartokinase superfamily Pfam (PF00583): GCN5-related N-acetyltransferase; Specificity unclear.
     
 0.658
efp
Putative elongation factor P; Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
 
   
 0.631
azo1431
Conserved hypothetical protein; TREMBL: Q8Y0P5 : 81% identity, 90% similarity. Probable Cell division protein ftsH homolog (EC 3.4.24.-). InterPro:IPR003593; AAA_ATPase. IPR003959; AAA_ATPase_centr. Pfam: PF00004; AAA; ATPase family associated with various SMART: SM00382; AAA; Absence of transmembrane helices (TMHMM predicted) NON secretory protein ruvB: Holliday junction DNA helicase Ru; Specificity unclear.
    
 
 0.597
norQ
Nitric-oxide reductase ATP/GTP binding component,NorQ. 68% FGGY_kin. TMHMM:present SignalP: present; High confidence in function and specificity.
    
 
 0.597
speE2
Probable spermidine synthase; Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine; Belongs to the spermidine/spermine synthase family.
  
 
 0.590
speE1
Spermidine synthase (Putrescine aminopropyltransferase),; Conserved hypothetical protein.
  
 
 0.581
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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