STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rpoDRNA polymerase sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. (662 aa)    
Predicted Functional Partners:
rpoB
DNA-directed RNA polymerase; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
 
 
 0.977
rpoA
DNA-directed RNA polymerase; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
 
 
 0.969
rpoZ
DNA-directed RNA polymerase; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
 
 
 
 0.962
rpoC
DNA-directed RNA polymerase; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
 
 
 0.960
dnaG
DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.
 
  
 0.951
nusA
Putative N utilization substance protein A; Participates in both transcription termination and antitermination.
 
 
 0.942
vfr
Probable cyclic amp receptor-like protein,; High confidence in function and specificity.
    
 
 0.913
sspA2
Probable Stringent starvation protein A. Homology to sspA of E. coli of 43% (sprot|SSPA_ECOLI). FORMS AN EQUIMOLAR COMPLEX WITH THE RNA POLYMERASE HOLOENZYME (RNAP) BUT NOT WITH THE CORE ENZYME. IT IS SYNTHESIZED PREDOMINANTLY WHEN CELLS ARE EXPOSED TO AMINO ACID STARVATION AT WHICH TIME IT ACCOUNTS FOR OVER 50% OF THE TOTAL PROTEIN SYNTHESIZED. Pfam: Glutatione S-transferase,N-terminale domaine no TMHs; Family membership; Belongs to the GST superfamily.
  
 
   0.906
ada
Methylated-DNA--[protein]-cysteine S-methyltransferase (6-O-methylguanine-DNA methyltransferase) (O-6-methylguanine-DNA-alkyltransferase) InterPro: Methylated-DNA--protein-cysteine methyltransferase; High confidence in function and specificity.
   
   0.894
soxR
Probable redox-sensitive transcriptional activator,; High confidence in function and specificity.
   
 
 0.874
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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