| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| azo0788 | azo3229 | azo0788 | azo3229 | Probable acyltransferase; Acyl-[acyl-carrier protein] can also acts as acyl donor.The animal enzyme is specific for the transfer of unsaturated fatty acyl groups. Catalytic Activity:-Acyl-CoA + 1-acyl-sn-glycerol 3-phosphate = CoA + 1,2-diacyl-sn-glycerol 3-phosphate. Entry name TREMBL:Q82VB2 Prim. accession # Q82VB2 InterPro:-IPR002123; Acyltransferase. Pfam:- PF01553; Acyltransferase; 1. Identity:- 56% Prediction: Signal peptide Signal peptide probability: 0.907 Number of predicted TMHs: 1; Family membership. | Putative hydrolase; Probable Hydrogenase expression/formation protein hupH. SIMILARITY:Belongs to the hupH/hyaF family SPROT:P48340: 37% identity, 54% similarity InterPro: IPR002725; DUF45. Pfam: PF01863; DUF45 Nonsecretory protein (Signal P predicted) No transmembrane helices (TMHMM predicted); High confidence in function and specificity. | 0.643 |
| azo1483 | azo3229 | azo1483 | azo3229 | Putative 5'-nucleotidase Has Signal Peptide. Has PF02872, 5'-nucleotidase, C-terminal domain; IPR008334, 5'-Nucleotdase_C; 5'-nucleotidases are enzymes that catalyze the hydrolysis ofphosphate esterified at carbon 5' of the ribose and deoxyribose portions of nucleotide molecules. 5'-nucleotidase is a ubiquitous enzyme found in a wide variety of species and which occurs in different cellular locations. The extracellular 5'-nucleotidase from mammals and electric ray isozyme is a homodimeric disulphide-bonded glycoprotein attached to the membrane by a GPI-anchor, and requires zinc for its [...] | Putative hydrolase; Probable Hydrogenase expression/formation protein hupH. SIMILARITY:Belongs to the hupH/hyaF family SPROT:P48340: 37% identity, 54% similarity InterPro: IPR002725; DUF45. Pfam: PF01863; DUF45 Nonsecretory protein (Signal P predicted) No transmembrane helices (TMHMM predicted); High confidence in function and specificity. | 0.496 |
| azo1483 | azo3230 | azo1483 | azo3230 | Putative 5'-nucleotidase Has Signal Peptide. Has PF02872, 5'-nucleotidase, C-terminal domain; IPR008334, 5'-Nucleotdase_C; 5'-nucleotidases are enzymes that catalyze the hydrolysis ofphosphate esterified at carbon 5' of the ribose and deoxyribose portions of nucleotide molecules. 5'-nucleotidase is a ubiquitous enzyme found in a wide variety of species and which occurs in different cellular locations. The extracellular 5'-nucleotidase from mammals and electric ray isozyme is a homodimeric disulphide-bonded glycoprotein attached to the membrane by a GPI-anchor, and requires zinc for its [...] | Probable Hypothetical protein Ta0487. trembl:Q7W4W1:50% identity, 62% similarity InterPro:IPR001453; MoCF_biosynth. Pfam: PF00994; MoCF_biosynth; 1. Eukaryotic and prokaryotic molybdoenzymes require a molybdopterin cofactor (MoCF) for their activity. The biosynthesis of this cofactor involves a complex multistep enzymatic pathway. One of the eukaryotic proteins involved in this pathway is the Drosophila protein cinnamon molyb_syn: molybdenum cofactor synthe No signal peptide. No transmembrane helices; Function unclear. | 0.550 |
| azo1483 | ssm | azo1483 | azo2819 | Putative 5'-nucleotidase Has Signal Peptide. Has PF02872, 5'-nucleotidase, C-terminal domain; IPR008334, 5'-Nucleotdase_C; 5'-nucleotidases are enzymes that catalyze the hydrolysis ofphosphate esterified at carbon 5' of the ribose and deoxyribose portions of nucleotide molecules. 5'-nucleotidase is a ubiquitous enzyme found in a wide variety of species and which occurs in different cellular locations. The extracellular 5'-nucleotidase from mammals and electric ray isozyme is a homodimeric disulphide-bonded glycoprotein attached to the membrane by a GPI-anchor, and requires zinc for its [...] | Putative hydrolase; TREMBL:Q7NQN9: 48% identity; 66% similarity SPROT:P53078: 28% identity, 47% similarity InterPro :IPR006402; HAD-SF-IA-v3. IPR005833: Hlgnase/hydrlase. IPR005834: Hydrolase. IPR010237; Pyr-5-nucltdase. Pfam PF00702; Hydrolase; 1. PRINTS PR00413; HADHALOGNASE. TIGRFAMs TIGR01509; HAD-SF-IA-v3; 1. TIGR01993; Pyr-5-nucltdase; SSM1 protein. No signal peptide. No transmembrane helices. Could be an enzyme that inactivates 6-azauracil by modifying it. InterPro: Haloacid dehalogenase/epoxide hydrolase family otsB: trehalose-phosphatase; Family membership. | 0.499 |
| azo1483 | surE | azo1483 | azo1087 | Putative 5'-nucleotidase Has Signal Peptide. Has PF02872, 5'-nucleotidase, C-terminal domain; IPR008334, 5'-Nucleotdase_C; 5'-nucleotidases are enzymes that catalyze the hydrolysis ofphosphate esterified at carbon 5' of the ribose and deoxyribose portions of nucleotide molecules. 5'-nucleotidase is a ubiquitous enzyme found in a wide variety of species and which occurs in different cellular locations. The extracellular 5'-nucleotidase from mammals and electric ray isozyme is a homodimeric disulphide-bonded glycoprotein attached to the membrane by a GPI-anchor, and requires zinc for its [...] | Phosphoric-monoester phosphohydrolase; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.576 |
| azo3229 | azo0788 | azo3229 | azo0788 | Putative hydrolase; Probable Hydrogenase expression/formation protein hupH. SIMILARITY:Belongs to the hupH/hyaF family SPROT:P48340: 37% identity, 54% similarity InterPro: IPR002725; DUF45. Pfam: PF01863; DUF45 Nonsecretory protein (Signal P predicted) No transmembrane helices (TMHMM predicted); High confidence in function and specificity. | Probable acyltransferase; Acyl-[acyl-carrier protein] can also acts as acyl donor.The animal enzyme is specific for the transfer of unsaturated fatty acyl groups. Catalytic Activity:-Acyl-CoA + 1-acyl-sn-glycerol 3-phosphate = CoA + 1,2-diacyl-sn-glycerol 3-phosphate. Entry name TREMBL:Q82VB2 Prim. accession # Q82VB2 InterPro:-IPR002123; Acyltransferase. Pfam:- PF01553; Acyltransferase; 1. Identity:- 56% Prediction: Signal peptide Signal peptide probability: 0.907 Number of predicted TMHs: 1; Family membership. | 0.643 |
| azo3229 | azo1483 | azo3229 | azo1483 | Putative hydrolase; Probable Hydrogenase expression/formation protein hupH. SIMILARITY:Belongs to the hupH/hyaF family SPROT:P48340: 37% identity, 54% similarity InterPro: IPR002725; DUF45. Pfam: PF01863; DUF45 Nonsecretory protein (Signal P predicted) No transmembrane helices (TMHMM predicted); High confidence in function and specificity. | Putative 5'-nucleotidase Has Signal Peptide. Has PF02872, 5'-nucleotidase, C-terminal domain; IPR008334, 5'-Nucleotdase_C; 5'-nucleotidases are enzymes that catalyze the hydrolysis ofphosphate esterified at carbon 5' of the ribose and deoxyribose portions of nucleotide molecules. 5'-nucleotidase is a ubiquitous enzyme found in a wide variety of species and which occurs in different cellular locations. The extracellular 5'-nucleotidase from mammals and electric ray isozyme is a homodimeric disulphide-bonded glycoprotein attached to the membrane by a GPI-anchor, and requires zinc for its [...] | 0.496 |
| azo3229 | azo3230 | azo3229 | azo3230 | Putative hydrolase; Probable Hydrogenase expression/formation protein hupH. SIMILARITY:Belongs to the hupH/hyaF family SPROT:P48340: 37% identity, 54% similarity InterPro: IPR002725; DUF45. Pfam: PF01863; DUF45 Nonsecretory protein (Signal P predicted) No transmembrane helices (TMHMM predicted); High confidence in function and specificity. | Probable Hypothetical protein Ta0487. trembl:Q7W4W1:50% identity, 62% similarity InterPro:IPR001453; MoCF_biosynth. Pfam: PF00994; MoCF_biosynth; 1. Eukaryotic and prokaryotic molybdoenzymes require a molybdopterin cofactor (MoCF) for their activity. The biosynthesis of this cofactor involves a complex multistep enzymatic pathway. One of the eukaryotic proteins involved in this pathway is the Drosophila protein cinnamon molyb_syn: molybdenum cofactor synthe No signal peptide. No transmembrane helices; Function unclear. | 0.677 |
| azo3229 | azo3231 | azo3229 | azo3231 | Putative hydrolase; Probable Hydrogenase expression/formation protein hupH. SIMILARITY:Belongs to the hupH/hyaF family SPROT:P48340: 37% identity, 54% similarity InterPro: IPR002725; DUF45. Pfam: PF01863; DUF45 Nonsecretory protein (Signal P predicted) No transmembrane helices (TMHMM predicted); High confidence in function and specificity. | Conserved hypothetical membrane protein. Homology to ebA4352 of Azoarcus sp. EbN1 of 31% (gnl|keqq|eba:ebA4352(KEGG)). Has PF04401, Protein of unknown function (DUF540); IPR007496 DUF540; Uncharacterised bacterial integral membrane protein,possibly involved in cysteine biosynthesis. Speculated to be involved in sulphate transport. no signal peptide. 6 TMHs; Conserved hypothetical protein. | 0.706 |
| azo3229 | azo3233 | azo3229 | azo3233 | Putative hydrolase; Probable Hydrogenase expression/formation protein hupH. SIMILARITY:Belongs to the hupH/hyaF family SPROT:P48340: 37% identity, 54% similarity InterPro: IPR002725; DUF45. Pfam: PF01863; DUF45 Nonsecretory protein (Signal P predicted) No transmembrane helices (TMHMM predicted); High confidence in function and specificity. | Conserved hypothetical membrane protein. Homology to ne1459 of N. europaea of 49% (trembl|Q82UM4). Pfam: Cytochrome C assembly protein. no signal peptide. 8 TMHs; Conserved hypothetical protein. | 0.478 |
| azo3229 | ffh | azo3229 | azo3232 | Putative hydrolase; Probable Hydrogenase expression/formation protein hupH. SIMILARITY:Belongs to the hupH/hyaF family SPROT:P48340: 37% identity, 54% similarity InterPro: IPR002725; DUF45. Pfam: PF01863; DUF45 Nonsecretory protein (Signal P predicted) No transmembrane helices (TMHMM predicted); High confidence in function and specificity. | Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual componen [...] | 0.663 |
| azo3229 | gloA2 | azo3229 | azo3228 | Putative hydrolase; Probable Hydrogenase expression/formation protein hupH. SIMILARITY:Belongs to the hupH/hyaF family SPROT:P48340: 37% identity, 54% similarity InterPro: IPR002725; DUF45. Pfam: PF01863; DUF45 Nonsecretory protein (Signal P predicted) No transmembrane helices (TMHMM predicted); High confidence in function and specificity. | Lactoylglutathione lyase; Glyoxalase I catalyzes the first step of the glyoxal pathway. S-lactoylglutathione is then converted by glyoxalase II to lactic acid. Similar to trembl|Q9HY85 (74%) and to sprot|LGUL_NEIMA (70%). Pfam (PF00903): Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily ProDom (PD002334): Glyoxalase I; High confidence in function and specificity. | 0.772 |
| azo3229 | ndk | azo3229 | azo0923 | Putative hydrolase; Probable Hydrogenase expression/formation protein hupH. SIMILARITY:Belongs to the hupH/hyaF family SPROT:P48340: 37% identity, 54% similarity InterPro: IPR002725; DUF45. Pfam: PF01863; DUF45 Nonsecretory protein (Signal P predicted) No transmembrane helices (TMHMM predicted); High confidence in function and specificity. | Nucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.420 |
| azo3229 | ssm | azo3229 | azo2819 | Putative hydrolase; Probable Hydrogenase expression/formation protein hupH. SIMILARITY:Belongs to the hupH/hyaF family SPROT:P48340: 37% identity, 54% similarity InterPro: IPR002725; DUF45. Pfam: PF01863; DUF45 Nonsecretory protein (Signal P predicted) No transmembrane helices (TMHMM predicted); High confidence in function and specificity. | Putative hydrolase; TREMBL:Q7NQN9: 48% identity; 66% similarity SPROT:P53078: 28% identity, 47% similarity InterPro :IPR006402; HAD-SF-IA-v3. IPR005833: Hlgnase/hydrlase. IPR005834: Hydrolase. IPR010237; Pyr-5-nucltdase. Pfam PF00702; Hydrolase; 1. PRINTS PR00413; HADHALOGNASE. TIGRFAMs TIGR01509; HAD-SF-IA-v3; 1. TIGR01993; Pyr-5-nucltdase; SSM1 protein. No signal peptide. No transmembrane helices. Could be an enzyme that inactivates 6-azauracil by modifying it. InterPro: Haloacid dehalogenase/epoxide hydrolase family otsB: trehalose-phosphatase; Family membership. | 0.425 |
| azo3229 | surE | azo3229 | azo1087 | Putative hydrolase; Probable Hydrogenase expression/formation protein hupH. SIMILARITY:Belongs to the hupH/hyaF family SPROT:P48340: 37% identity, 54% similarity InterPro: IPR002725; DUF45. Pfam: PF01863; DUF45 Nonsecretory protein (Signal P predicted) No transmembrane helices (TMHMM predicted); High confidence in function and specificity. | Phosphoric-monoester phosphohydrolase; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.420 |
| azo3230 | azo1483 | azo3230 | azo1483 | Probable Hypothetical protein Ta0487. trembl:Q7W4W1:50% identity, 62% similarity InterPro:IPR001453; MoCF_biosynth. Pfam: PF00994; MoCF_biosynth; 1. Eukaryotic and prokaryotic molybdoenzymes require a molybdopterin cofactor (MoCF) for their activity. The biosynthesis of this cofactor involves a complex multistep enzymatic pathway. One of the eukaryotic proteins involved in this pathway is the Drosophila protein cinnamon molyb_syn: molybdenum cofactor synthe No signal peptide. No transmembrane helices; Function unclear. | Putative 5'-nucleotidase Has Signal Peptide. Has PF02872, 5'-nucleotidase, C-terminal domain; IPR008334, 5'-Nucleotdase_C; 5'-nucleotidases are enzymes that catalyze the hydrolysis ofphosphate esterified at carbon 5' of the ribose and deoxyribose portions of nucleotide molecules. 5'-nucleotidase is a ubiquitous enzyme found in a wide variety of species and which occurs in different cellular locations. The extracellular 5'-nucleotidase from mammals and electric ray isozyme is a homodimeric disulphide-bonded glycoprotein attached to the membrane by a GPI-anchor, and requires zinc for its [...] | 0.550 |
| azo3230 | azo3229 | azo3230 | azo3229 | Probable Hypothetical protein Ta0487. trembl:Q7W4W1:50% identity, 62% similarity InterPro:IPR001453; MoCF_biosynth. Pfam: PF00994; MoCF_biosynth; 1. Eukaryotic and prokaryotic molybdoenzymes require a molybdopterin cofactor (MoCF) for their activity. The biosynthesis of this cofactor involves a complex multistep enzymatic pathway. One of the eukaryotic proteins involved in this pathway is the Drosophila protein cinnamon molyb_syn: molybdenum cofactor synthe No signal peptide. No transmembrane helices; Function unclear. | Putative hydrolase; Probable Hydrogenase expression/formation protein hupH. SIMILARITY:Belongs to the hupH/hyaF family SPROT:P48340: 37% identity, 54% similarity InterPro: IPR002725; DUF45. Pfam: PF01863; DUF45 Nonsecretory protein (Signal P predicted) No transmembrane helices (TMHMM predicted); High confidence in function and specificity. | 0.677 |
| azo3230 | azo3231 | azo3230 | azo3231 | Probable Hypothetical protein Ta0487. trembl:Q7W4W1:50% identity, 62% similarity InterPro:IPR001453; MoCF_biosynth. Pfam: PF00994; MoCF_biosynth; 1. Eukaryotic and prokaryotic molybdoenzymes require a molybdopterin cofactor (MoCF) for their activity. The biosynthesis of this cofactor involves a complex multistep enzymatic pathway. One of the eukaryotic proteins involved in this pathway is the Drosophila protein cinnamon molyb_syn: molybdenum cofactor synthe No signal peptide. No transmembrane helices; Function unclear. | Conserved hypothetical membrane protein. Homology to ebA4352 of Azoarcus sp. EbN1 of 31% (gnl|keqq|eba:ebA4352(KEGG)). Has PF04401, Protein of unknown function (DUF540); IPR007496 DUF540; Uncharacterised bacterial integral membrane protein,possibly involved in cysteine biosynthesis. Speculated to be involved in sulphate transport. no signal peptide. 6 TMHs; Conserved hypothetical protein. | 0.822 |
| azo3230 | azo3233 | azo3230 | azo3233 | Probable Hypothetical protein Ta0487. trembl:Q7W4W1:50% identity, 62% similarity InterPro:IPR001453; MoCF_biosynth. Pfam: PF00994; MoCF_biosynth; 1. Eukaryotic and prokaryotic molybdoenzymes require a molybdopterin cofactor (MoCF) for their activity. The biosynthesis of this cofactor involves a complex multistep enzymatic pathway. One of the eukaryotic proteins involved in this pathway is the Drosophila protein cinnamon molyb_syn: molybdenum cofactor synthe No signal peptide. No transmembrane helices; Function unclear. | Conserved hypothetical membrane protein. Homology to ne1459 of N. europaea of 49% (trembl|Q82UM4). Pfam: Cytochrome C assembly protein. no signal peptide. 8 TMHs; Conserved hypothetical protein. | 0.562 |
| azo3230 | ffh | azo3230 | azo3232 | Probable Hypothetical protein Ta0487. trembl:Q7W4W1:50% identity, 62% similarity InterPro:IPR001453; MoCF_biosynth. Pfam: PF00994; MoCF_biosynth; 1. Eukaryotic and prokaryotic molybdoenzymes require a molybdopterin cofactor (MoCF) for their activity. The biosynthesis of this cofactor involves a complex multistep enzymatic pathway. One of the eukaryotic proteins involved in this pathway is the Drosophila protein cinnamon molyb_syn: molybdenum cofactor synthe No signal peptide. No transmembrane helices; Function unclear. | Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual componen [...] | 0.794 |