STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
azo3245Conserved hypothetical secreted protein. Homology to ebA4328 of Azoarcus sp. EbN1 of 59% (gnl|keqq|eba:ebA4328(KEGG)). no domains predicted. signal peptide. TMH in signal peptide. (386 aa)    
Predicted Functional Partners:
tesA1
Probable acyl-CoA thioesterase. Homology to tesA of E. coli of 42% (sprot|TESA_ECOLI) Hydrolyzes long chain acyl thioesters (c12-c18): 2-lysophosphatidylcholine + h(2)o = glycerophosphocholine + a fatty acid anion. InterPro: GDSL lipolytic enzyme (IPR001087) Pfam: Lipase/Acylhydrolase with GDSL-like motif signal peptide no TMH; Family membership.
  
 0.854
tesA2
Putative acyl-CoA thioesterase. Homology to tesA of E. coli of 32% (sprot|TESA_ECOLI) Hydrolyzes long chain acyl thioesters (c12-c18): 2-lysophosphatidylcholine + h(2)o = glycerophosphocholine + a fatty acid anion. InterPro: GDSL lipolytic enzyme (IPR001087) Pfam: Lipase/Acylhydrolase GDSL-like motif signal peptide no TMH; Family membership.
  
 0.854
argB
ArgB protein; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily.
       0.773
fadD4
Long-chain-fatty-acid-CoA ligase; Esterification, concomitant with transport, of exogenous long-chain fatty acids into metabolically active coa thioesters for subsequent degradation or incorporation into phospholipids, TREMBL:Q8UET3 (39% identity); TREMBL:Q988H2 (38% identity). InterPro (IPR000873): AMP-dependent synthetase and ligase Pfam (PF00501): AMP-binding enzyme; High confidence in function and specificity.
 
     0.765
azo3252
Conserved hypothetical protein. Homology to ne2163 of N. europaea of 42% (trembl|Q82SY3). Pfam: Poshpopantetheine attachment site. A 4'-phosphopantetheine prosthetic group is attached through a serine. This prosthetic group acts as a a 'swinging arm' for the attachment of activated fatty acid and amino-acid groups. This domain forms a four helix bundle. no signal peptide. no TMHS.
  
 
 
 0.726
azo3268
Glycosyltransferase; InterPro: Glycosyl transferases group 1; Specificity unclear.
  
     0.723
azo0984
Conserved hypothetical secreted protein. Homology to NE1634 of Nitrosomonas europaea of 34% (trembl|Q82U71(SRS)) No domains predicted. No TMHs Signal peptide present; Conserved hypothetical protein.
  
     0.695
guaA
GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.
    
  0.679
lysA1
Diaminopimelate decarboxylase,; Specificity unclear.
 
     0.679
azo3276
Conserved hypothetical protein; Possibly related to cell surface polysaccharide biosynthesis, due to the presence of the gene in a polysaccharide synthesis gene cluster; Function unclear.
  
     0.655
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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