STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
azo3253Conserved hypothetical protein. Homology to Mmc102002678 of Magnetococcus sp. MC-1 of 44% (gi|48831833|ref|ZP_00288884.1|(NBCI ENTREZ)). No domains predicted. No TMHs. No signal peptide. (411 aa)    
Predicted Functional Partners:
azo3251
Conserved hypothetical protein; Probable Adenylate cyclase (EC 4.6.1.1) (ATP pyrophosphate-lyase) (Adenylyl cyclase). TREMBL:Q82SY4:40% identity, 57% similarity. InterPro:IPR000379; Ser_estrs Pfam:UPF0007:Uncharacterized protein family UPF000 thiE: thiamine-phosphate pyrophosphorylas No transmembrane helices; Function unclear.
 
 
  0.862
azo3250
Conserved hypothetical protein. Homology to ne2161 of N. europaea of 45% (trembl|Q82SY5). Interpro: Esterase/lipase/thioesterase family. no damians predicted. no signal peptide. no TMHs.
 
  
  0.859
azo3252
Conserved hypothetical protein. Homology to ne2163 of N. europaea of 42% (trembl|Q82SY3). Pfam: Poshpopantetheine attachment site. A 4'-phosphopantetheine prosthetic group is attached through a serine. This prosthetic group acts as a a 'swinging arm' for the attachment of activated fatty acid and amino-acid groups. This domain forms a four helix bundle. no signal peptide. no TMHS.
 
 
   0.832
azo3256
Conserved hypothetical polysaccharide biosynthesis protein, related to GumJ. Homology to ebA4295 of Azoarcus sp. EbN1 of 42%. Pfam: Polysaccharide biosynthesis protein. Members of this family are integral membrane proteins. Many members of the family are implicated in production of polysaccharide. The family includes RfbX part of the O antigen biosynthesis operon. The family includes SpoVB from Bacillus subtilis SP5B_BACSU, which is involved in spore cortex biosynthesis. No signal peptide. 10 TMHs; Family membership.
 
 
 0.788
azo3254
Hypothetical protein predicted by Glimmer/Critica; May be related to biosynthesos of cell surface carbohydrates / polysaccharides.
       0.773
azo3267
Conserved hypothetical membrane protein. Homology to RferDRAFT_3275 of Rhodoferax ferrireducens of 46%. Pfam: O-Antigen Polymerase. This group of bacterial proteins is involved in the synthesis of O-antigen, a lipopolysaccharide found in the outer membrane in gram-negative bacteria. The enzyme is coded for by the gene wzy which is part of the O-antigen gene cluster. No signal peptide. 9 TMHs; Family membership.
 
 
  0.757
azo3276
Conserved hypothetical protein; Possibly related to cell surface polysaccharide biosynthesis, due to the presence of the gene in a polysaccharide synthesis gene cluster; Function unclear.
 
     0.614
mnaA
UDP-N-acetylglucosamine 2-epimerase (EC 5.1.3.14) (UDP-GlcNAc-2- epimerase). Catalyzes the reversible epimerization at C-2 of UDP-N- acetylglucosamine (UDP-GlcNAc) and thereby provides bacteria with UDP-N-acetylmannosamine (UDP-ManNAc) the activated donor of ManNAc residues (By similarity). InterPro: UDP-N-acetylglucosamine 2-epimerase; High confidence in function and specificity.
 
 
 0.611
azo3275
Conserved hypothetical membrane protein. Homology to NE1797 of Nitrosomonas europaea of 33% (trembl|Q82TS7(SRS)). no domains predicted. signal peptide. 7 TMHs; Conserved hypothetical protein.
 
    0.608
glgB1
Putative 1,4-alpha-glucan branching enzyme; Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position; Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
   
  0.593
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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