Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
azo3285Conserved hypothetical secreted protein. Homology to NE2243 of Nitrosomonas europaea of 43% (trembl|Q82SR4(SRS). No domains predicted. Signal peptide present. No TMH reported present; Conserved hypothetical protein. (437 aa)    
Predicted Functional Partners:
azo3287
Conserved hypothetical secreted protein. Homology to NE2245 of Nitrosomonas europaea of 51% (tremble:Q82SR2). No domains predicted. Signal peptide present. No TMH present; Conserved hypothetical protein.
 
   
 0.893
azo1307
Probable vgr-related protein,41% identity (55% similarity) to TrEMBL;Q7NY43. TrEMBL;Q8XSF8 Has (IPR006533 Rhs_Vgr)PF04524:Protein of unknown function, DUF586;This family contains a conserved region in several bacterial proteins of unknown function. Coils2 program predicts presence of a coiled coil.
   
  0.840
vgrG
Probable vgr-related protein, 44% identity(54% similarity) to TrEMBL; Q7P238.TrEMBL;Q8XRU3(44% identity). Signal Peptide Present. Has SMART;SM00438,Repressor of transcription;IPR000967, Znf_NFX1;This domain is presumed to be a zinc binding domain. The following pattern describes the zinc finger: C-X(1-6)-H-X-C-X3-C(H/C)-X(3-4)-(H/C)-X(1-10)-C,where X can be any amino acid, and numbers in brackets indicate the number of residues. The two position can be either his or cys. This domain is found in the human transcriptional repressor NK-X1, a repressor of HLA-DRA transcription; the Drosoph [...]
   
  0.840
azo3876
Conserved hypothetical protein; Rhs family protein,vgrG 38% identity(54% similarity) to TrEMBL;Q747T8. TrEMBL;O52672. Signal Peptide Present. Has PF04524, Protein of unknown function,DUF586;IPR006533, Rhs_Vgr:This family contains a conserved region in several bacterial proteins of unknown function. These sequences represent the Vgr family of proteins,associated with some classes of Rhs elements. This model does not include a large octapeptide repeat region,VGXXXXXX, found in the Vgr of Rhs classes G and E. Has PF06715, Gp5 C-terminal repeat (2 copies);IPR010609,Gp5_C:This repeat compos [...]
   
  0.840
azo3286
ATP-binding cassette (ABC) transporters form a large family of proteins responsible for translocation of a variety of compounds across biological membranes. They are composed of two transmembrane domains responsible for binding and transport and two nucleotide-binding domains responsible for coupling the energy of ATP hydrolysis to conformational changes in the TMDs. Similar to TREMBL:Q82SR3 (67% identity); TREMBL:Q92NU9 (48% identity); SWISSPROT:Q58206 (45% identity). InterPro (IPR003439): ABC transporter. InterPro (IPR001687): ATP/GTP-binding site motif A (P-loop). InterPro (IPR00359 [...]
 
     0.836
azo1311
Conserved hypothetical protein Has 2 PF05488 PAAR motif(IPR008727);This motif is found usually in pairs in a family of bacterial membrane proteins. It is also found as a triplet of tandem repeats comprising the entire length in a another family of hypothetical proteins; Function unclear.
     
  0.744
lolE3
Permease component of an ABC transporter system; Part of a lipoprotein translocation system (translocates lipoproteins from the inner membrane to periplasmic chaperone, LolA, which transfers the lipoproteins to an outer membrane receptor, LolB, which anchors the lipoprotein to the outer membrane of the Gram-negative bacterial cell envelope); Specificity unclear.
 
     0.725
azo3176
Permease component of an ABC-transporter system; Region start changed from 3485680 to 3485581 (99 bases).
 
     0.716
azo3284
Conserved hypothetical protein. Homology to ne2229 of N. europaea of 38% (trembl|Q82SS7). no domains predicted. no signal peptide. no TMHs.
 
     0.669
azo1545
Hypotheical protein. No good homology of the entire protein with the data base. No domains predicted. No THs. No signal peptide.
  
 
 0.590
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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