STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
azo3296Conserved hypothetical membrane protein. Homology to RS03338 of Ralstonia solanacearum of 36% (trembl|Q8Y2G6(SRS)). No domains predicted. No signal peptide. 1 TMHs; Conserved hypothetical protein. (217 aa)    
Predicted Functional Partners:
coxB
Conserved hypothetical cytochrome c oxidase,subunit II; Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).
 
 
 0.976
azo3295
Putative Cytochrome aa3 oxidase assembly protein,42% Identity to TrEMBL;Q7P0G1, Q62F60. Has PF02628,Cytochrome oxidase assembly protein; IPR003780,COX15_CtaA; This is a family of integral membrane proteins. CtaA is required for cytochrome aa3 oxidase assembly in Bacillus subtilis. COX15 is required for cytochrome c oxidase assembly in yeast (P40086).
 
 
 0.974
azo3297
Conserved hypothetical secreted protein. Homology to NE1012 of N.europaea of 31% (tremble:Q82VQ4). No domains predicted. Signal peptide present. No TMHs; Conserved hypothetical protein.
 
  
 0.968
coxD
Putative protoheme IX farnesyltransferase; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
 
  
 0.945
coxG
CoxG protein; Cytochrome c oxidase assembly protein ctaG. Exerts its effect at some terminal stage of cytochrome c oxidase synthesis probably by being involved in the insertion of the copper B into subunit I (By similarity); High confidence in function and specificity.
 
 
 0.889
qoxB
Probable quniol oxidase, subunit II. Homology to qoxB of Rhodobacter sphaeroides of 41% (gi|4416093|gb|AAD20226.1|(NBCI ENTREZ)). InterPro: Cytochrome c oxidase subunit II (IPR002429); Cu(A) centre of cytochrome c oxidase, subunit II and nitrous oxide reductase (IPR001505). Pfam: Cytochrome c oxidase subunit II, periplasmic. no signal peptide. 2 TMHs; Family membership.
 
 
 0.881
azo3298
Conserved hypothetical membrane protein. Homology to rs0336 of R. solanacearum of 53% (trembl|Q8Y2G8(SRS)). no domains predicted. signal peptide. 1 TMH; Conserved hypothetical protein.
 
     0.819
senC
SCO1/SenC family protein; SCO2 protein homolog mitochondrial precursor. Acts as a copper chaperone transporting copper to the Cu(A) site on the cytochrome c oxidase subunit II (COX2). InterPro: SCO1/SenC TREMBL:Q8Y2G3: 56% identity, 74% similarity InterPro:IPR003782; SCO1_SenC. Pfam: PF02630; SCO1-SenC dsbE: periplasmic protein thiol:disulf Presence of signal peptide (SignalP predicted) No TMH's present; Family membership.
 
     0.809
coxC
Cytochrome c oxidase polypeptide III Subunits I II and III form the functional core of the enzyme complex. InterPro: Cytochrome c oxidase subunit III; High confidence in function and specificity.
 
  
 0.807
azo2154
Conserved hypothetical secreted protein. 33% similarity to TrEMBL Q8XQF8 PROBABLE SIGNAL PEPTIDE PROTEIN [RS05314] [Ralstonia solanacearum (Pseudomonas solanacearum)]. No domains predicted. Signal P reporting signal peptide present. No TMH reported being present; Conserved hypothetical protein.
  
 
 0.734
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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