STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
coxCCytochrome c oxidase polypeptide III Subunits I II and III form the functional core of the enzyme complex. InterPro: Cytochrome c oxidase subunit III; High confidence in function and specificity. (283 aa)    
Predicted Functional Partners:
qoxB
Probable quniol oxidase, subunit II. Homology to qoxB of Rhodobacter sphaeroides of 41% (gi|4416093|gb|AAD20226.1|(NBCI ENTREZ)). InterPro: Cytochrome c oxidase subunit II (IPR002429); Cu(A) centre of cytochrome c oxidase, subunit II and nitrous oxide reductase (IPR001505). Pfam: Cytochrome c oxidase subunit II, periplasmic. no signal peptide. 2 TMHs; Family membership.
 
 0.999
qoxA
Probable quinol oxidase, subunit I. Homology to qoxA of R. sphaeroides of 52% (trembl|Q9Z605). InterPro: Cytochrome c oxidase subunit III (IPR000298); Cytochrome coxidase, subunit I (IPR000883) Pfam: Cytochrom C and quinol oxidase poly polypeptide signal peptide 17 TMHs; Family membership; Belongs to the heme-copper respiratory oxidase family.
 0.999
coxA
Probable cytochrome c oxidase, subunit I; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
 0.999
coxB
Conserved hypothetical cytochrome c oxidase,subunit II; Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).
 
 0.999
petB
Ubiquinol-cytochrome c reductase cytochrome b protein; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
 
 0.998
coxD
Putative protoheme IX farnesyltransferase; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
 
 
 0.998
azo3295
Putative Cytochrome aa3 oxidase assembly protein,42% Identity to TrEMBL;Q7P0G1, Q62F60. Has PF02628,Cytochrome oxidase assembly protein; IPR003780,COX15_CtaA; This is a family of integral membrane proteins. CtaA is required for cytochrome aa3 oxidase assembly in Bacillus subtilis. COX15 is required for cytochrome c oxidase assembly in yeast (P40086).
 
 
 0.993
nuoH
Putative NADH-ubiquinone oxidoreductase chain H; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.
  
 
 0.991
nuoM
Putative NADH-ubiquinone oxidoreductase, chain M; NADH-quinone oxidoreductase chain M (EC 1.6.99.5) (NADH dehydrogenase I chain M) (NDH-1 chain M). NDH-1 shuttles electrons from NADH via FMN and iron- sulfur (Fe-S) centers to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred four hydrogen ions are translocated across the cytoplasmic membrane) and thus conserves the redox energy in a proton gradient. InterPro: NADH-Ubiquino [...]
  
 
 0.991
atpB
Probable ATP synthase A chain; Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
   
 
 0.990
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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