node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
azo3321 | trpC | azo3321 | azo3322 | Conserved hypothetical membrane protein. Homology to rsc2383 of R. solanacearum of 31% (trembl|Q8XWT7(SRS)). no domains predicted .no signal peptide. 1 TMHs; Conserved hypothetical protein. | Indole-3-glycerol phosphate synthase (IGPS). catalytic activity:1-(2-carboxyphenylamino)-1-deoxy-d-ribulose 5-phosphate = 1-(indol-3-yl)glycerol 3-phosphate + co(2) + h(2)o. pathway: tryptophan biosynthesis; fourth step. InterPro: Indole-3-glycerol phosphate synthase; High confidence in function and specificity; Belongs to the TrpC family. | 0.789 |
azo3321 | trpD | azo3321 | azo3323 | Conserved hypothetical membrane protein. Homology to rsc2383 of R. solanacearum of 31% (trembl|Q8XWT7(SRS)). no domains predicted .no signal peptide. 1 TMHs; Conserved hypothetical protein. | 1,4-alpha-glucan branching enzyme; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). | 0.784 |
azo3321 | trpG | azo3321 | azo3324 | Conserved hypothetical membrane protein. Homology to rsc2383 of R. solanacearum of 31% (trembl|Q8XWT7(SRS)). no domains predicted .no signal peptide. 1 TMHs; Conserved hypothetical protein. | Anthranilate synthase component II (Glutamine amido-transferase). catalytic activity: chorismate + l-glutamine = anthranilate + pyruvate + l-glutamate. pathway: tryptophan biosynthesis; first step. TIGRFAM: trpG_papA: glutamine amidotransferase of anthranilate synthase or para-aminobenzoate synthase; High confidence in function and specificity. | 0.745 |
azo3364 | pabB | azo3364 | azo0198 | The glycosyl transferase family includes anthranilate phosphoribosyltransferase (TrpD, EC: 2.4.2.18) and thymidine phosphorylase (EC: 2.4.2.2). All these proteins can transfer a phosphorylated ribose substrate. Similar to sprot|YBIB_ECOLI (40%) and to sprot|TRPD_SULSO (25%). Pfam (PF02885): Glycosyl transferase, family 3; Family membership. | Para-aminobenzoate synthase component I (EC 4.1.3.-) (ADC synthase). CATALYZES THE BIOSYNTHESIS OF 4-AMINO-4-DEOXYCHORISMATE (ADC) FROM CHORISMATE AND GLUTAMINE. InterPro: Anthranilate synthase component I and chorismate binding enzyme pabB: para-aminobenzoate synthase component I; Specificity unclear. | 0.995 |
azo3364 | pheA | azo3364 | azo1068 | The glycosyl transferase family includes anthranilate phosphoribosyltransferase (TrpD, EC: 2.4.2.18) and thymidine phosphorylase (EC: 2.4.2.2). All these proteins can transfer a phosphorylated ribose substrate. Similar to sprot|YBIB_ECOLI (40%) and to sprot|TRPD_SULSO (25%). Pfam (PF02885): Glycosyl transferase, family 3; Family membership. | Bifunctional chorismate mutase/prephenate dehydratase P-protein, pheA,; High confidence in function and specificity. | 0.837 |
azo3364 | trpA | azo3364 | azo1048 | The glycosyl transferase family includes anthranilate phosphoribosyltransferase (TrpD, EC: 2.4.2.18) and thymidine phosphorylase (EC: 2.4.2.2). All these proteins can transfer a phosphorylated ribose substrate. Similar to sprot|YBIB_ECOLI (40%) and to sprot|TRPD_SULSO (25%). Pfam (PF02885): Glycosyl transferase, family 3; Family membership. | TrpA protein; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.884 |
azo3364 | trpB | azo3364 | azo1047 | The glycosyl transferase family includes anthranilate phosphoribosyltransferase (TrpD, EC: 2.4.2.18) and thymidine phosphorylase (EC: 2.4.2.2). All these proteins can transfer a phosphorylated ribose substrate. Similar to sprot|YBIB_ECOLI (40%) and to sprot|TRPD_SULSO (25%). Pfam (PF02885): Glycosyl transferase, family 3; Family membership. | TrpB protein; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.927 |
azo3364 | trpC | azo3364 | azo3322 | The glycosyl transferase family includes anthranilate phosphoribosyltransferase (TrpD, EC: 2.4.2.18) and thymidine phosphorylase (EC: 2.4.2.2). All these proteins can transfer a phosphorylated ribose substrate. Similar to sprot|YBIB_ECOLI (40%) and to sprot|TRPD_SULSO (25%). Pfam (PF02885): Glycosyl transferase, family 3; Family membership. | Indole-3-glycerol phosphate synthase (IGPS). catalytic activity:1-(2-carboxyphenylamino)-1-deoxy-d-ribulose 5-phosphate = 1-(indol-3-yl)glycerol 3-phosphate + co(2) + h(2)o. pathway: tryptophan biosynthesis; fourth step. InterPro: Indole-3-glycerol phosphate synthase; High confidence in function and specificity; Belongs to the TrpC family. | 0.928 |
azo3364 | trpD | azo3364 | azo3323 | The glycosyl transferase family includes anthranilate phosphoribosyltransferase (TrpD, EC: 2.4.2.18) and thymidine phosphorylase (EC: 2.4.2.2). All these proteins can transfer a phosphorylated ribose substrate. Similar to sprot|YBIB_ECOLI (40%) and to sprot|TRPD_SULSO (25%). Pfam (PF02885): Glycosyl transferase, family 3; Family membership. | 1,4-alpha-glucan branching enzyme; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). | 0.557 |
azo3364 | trpE | azo3364 | azo3325 | The glycosyl transferase family includes anthranilate phosphoribosyltransferase (TrpD, EC: 2.4.2.18) and thymidine phosphorylase (EC: 2.4.2.2). All these proteins can transfer a phosphorylated ribose substrate. Similar to sprot|YBIB_ECOLI (40%) and to sprot|TRPD_SULSO (25%). Pfam (PF02885): Glycosyl transferase, family 3; Family membership. | Anthranilate synthase; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia. | 0.974 |
azo3364 | trpF | azo3364 | azo1046 | The glycosyl transferase family includes anthranilate phosphoribosyltransferase (TrpD, EC: 2.4.2.18) and thymidine phosphorylase (EC: 2.4.2.2). All these proteins can transfer a phosphorylated ribose substrate. Similar to sprot|YBIB_ECOLI (40%) and to sprot|TRPD_SULSO (25%). Pfam (PF02885): Glycosyl transferase, family 3; Family membership. | N-(5-phosphoribosyl)anthranilate isomerase (PRAI) catalyzes the third step of tryptophan biosynthesis. Similar to sprot|TRPF_RALSO (56%) and to sprot|TRPF_PSEAE (58%). Pfam (PF00697): N-(5'phosphoribosyl)anthranilate isomerase (PRAI); High confidence in function and specificity. | 0.935 |
azo3364 | trpG | azo3364 | azo3324 | The glycosyl transferase family includes anthranilate phosphoribosyltransferase (TrpD, EC: 2.4.2.18) and thymidine phosphorylase (EC: 2.4.2.2). All these proteins can transfer a phosphorylated ribose substrate. Similar to sprot|YBIB_ECOLI (40%) and to sprot|TRPD_SULSO (25%). Pfam (PF02885): Glycosyl transferase, family 3; Family membership. | Anthranilate synthase component II (Glutamine amido-transferase). catalytic activity: chorismate + l-glutamine = anthranilate + pyruvate + l-glutamate. pathway: tryptophan biosynthesis; first step. TIGRFAM: trpG_papA: glutamine amidotransferase of anthranilate synthase or para-aminobenzoate synthase; High confidence in function and specificity. | 0.934 |
pabB | azo3364 | azo0198 | azo3364 | Para-aminobenzoate synthase component I (EC 4.1.3.-) (ADC synthase). CATALYZES THE BIOSYNTHESIS OF 4-AMINO-4-DEOXYCHORISMATE (ADC) FROM CHORISMATE AND GLUTAMINE. InterPro: Anthranilate synthase component I and chorismate binding enzyme pabB: para-aminobenzoate synthase component I; Specificity unclear. | The glycosyl transferase family includes anthranilate phosphoribosyltransferase (TrpD, EC: 2.4.2.18) and thymidine phosphorylase (EC: 2.4.2.2). All these proteins can transfer a phosphorylated ribose substrate. Similar to sprot|YBIB_ECOLI (40%) and to sprot|TRPD_SULSO (25%). Pfam (PF02885): Glycosyl transferase, family 3; Family membership. | 0.995 |
pabB | pheA | azo0198 | azo1068 | Para-aminobenzoate synthase component I (EC 4.1.3.-) (ADC synthase). CATALYZES THE BIOSYNTHESIS OF 4-AMINO-4-DEOXYCHORISMATE (ADC) FROM CHORISMATE AND GLUTAMINE. InterPro: Anthranilate synthase component I and chorismate binding enzyme pabB: para-aminobenzoate synthase component I; Specificity unclear. | Bifunctional chorismate mutase/prephenate dehydratase P-protein, pheA,; High confidence in function and specificity. | 0.981 |
pabB | trpA | azo0198 | azo1048 | Para-aminobenzoate synthase component I (EC 4.1.3.-) (ADC synthase). CATALYZES THE BIOSYNTHESIS OF 4-AMINO-4-DEOXYCHORISMATE (ADC) FROM CHORISMATE AND GLUTAMINE. InterPro: Anthranilate synthase component I and chorismate binding enzyme pabB: para-aminobenzoate synthase component I; Specificity unclear. | TrpA protein; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.974 |
pabB | trpB | azo0198 | azo1047 | Para-aminobenzoate synthase component I (EC 4.1.3.-) (ADC synthase). CATALYZES THE BIOSYNTHESIS OF 4-AMINO-4-DEOXYCHORISMATE (ADC) FROM CHORISMATE AND GLUTAMINE. InterPro: Anthranilate synthase component I and chorismate binding enzyme pabB: para-aminobenzoate synthase component I; Specificity unclear. | TrpB protein; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.972 |
pabB | trpC | azo0198 | azo3322 | Para-aminobenzoate synthase component I (EC 4.1.3.-) (ADC synthase). CATALYZES THE BIOSYNTHESIS OF 4-AMINO-4-DEOXYCHORISMATE (ADC) FROM CHORISMATE AND GLUTAMINE. InterPro: Anthranilate synthase component I and chorismate binding enzyme pabB: para-aminobenzoate synthase component I; Specificity unclear. | Indole-3-glycerol phosphate synthase (IGPS). catalytic activity:1-(2-carboxyphenylamino)-1-deoxy-d-ribulose 5-phosphate = 1-(indol-3-yl)glycerol 3-phosphate + co(2) + h(2)o. pathway: tryptophan biosynthesis; fourth step. InterPro: Indole-3-glycerol phosphate synthase; High confidence in function and specificity; Belongs to the TrpC family. | 0.997 |
pabB | trpD | azo0198 | azo3323 | Para-aminobenzoate synthase component I (EC 4.1.3.-) (ADC synthase). CATALYZES THE BIOSYNTHESIS OF 4-AMINO-4-DEOXYCHORISMATE (ADC) FROM CHORISMATE AND GLUTAMINE. InterPro: Anthranilate synthase component I and chorismate binding enzyme pabB: para-aminobenzoate synthase component I; Specificity unclear. | 1,4-alpha-glucan branching enzyme; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). | 0.998 |
pabB | trpE | azo0198 | azo3325 | Para-aminobenzoate synthase component I (EC 4.1.3.-) (ADC synthase). CATALYZES THE BIOSYNTHESIS OF 4-AMINO-4-DEOXYCHORISMATE (ADC) FROM CHORISMATE AND GLUTAMINE. InterPro: Anthranilate synthase component I and chorismate binding enzyme pabB: para-aminobenzoate synthase component I; Specificity unclear. | Anthranilate synthase; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia. | 0.926 |
pabB | trpF | azo0198 | azo1046 | Para-aminobenzoate synthase component I (EC 4.1.3.-) (ADC synthase). CATALYZES THE BIOSYNTHESIS OF 4-AMINO-4-DEOXYCHORISMATE (ADC) FROM CHORISMATE AND GLUTAMINE. InterPro: Anthranilate synthase component I and chorismate binding enzyme pabB: para-aminobenzoate synthase component I; Specificity unclear. | N-(5-phosphoribosyl)anthranilate isomerase (PRAI) catalyzes the third step of tryptophan biosynthesis. Similar to sprot|TRPF_RALSO (56%) and to sprot|TRPF_PSEAE (58%). Pfam (PF00697): N-(5'phosphoribosyl)anthranilate isomerase (PRAI); High confidence in function and specificity. | 0.975 |