STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
cbbZProbable phosphoglycolate phosphatase; Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress. Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family. (223 aa)    
Predicted Functional Partners:
rpe
Ribulose-phosphate 3-epimerase(also known as pentose-5-phosphate 3-epimerase, PPE or Rpe), is the enzyme that converts D-ribulose 5-phosphate into D-xylulose 5-phosphate in Calvin's reductive pentose phosphate cycle. 71%Ribul_P_3_epim. Pfam:PF00834; Ribul_P_3_epim; 1. TIGRFAMs:TIGR01163; rpe; 1; High confidence in function and specificity.
 
  
 0.913
azo1615
TREMBL:Q7VSFO: Probable hydrolase, 55% identity,63% similarity Phosphoglycolate phosphatase (PGP). InterPro:PR006402; HAD-SF-IA-v3. IPR006439; HAD_SF_A_v1. IPR005834; Hydrolase. Pfam:PF00702; Hydrolase; Haloacid dehaloginase like hydrolase TIGRFAMs:TIGR01549; HAD-SF-IA-v1; TIGR01509; HAD-SF-IA-v3; serB: phosphoserine phosphatase SerB hstdl_phs_rel: histidinol phosphatase-; Function unclear.
  
  
 
0.898
glcD1
Probable glycolate oxidase subunit glcD. Homology to glcD of E. coli of 64% (sprot|GLCD_ECOLI) InterPro: FAD linked oxidase C-terminal (IPR004113); FAD linked oxidase N-terminal (IPR006093) Pfam: FAD binding domain; FAD linked oxidase, C-terminal domain Tigrfam: glcD: glycolate oxidase subunit GlcD no signal peptide no TMHs; High confidence in function and specificity.
    
 0.882
glcF
Probable glycolate oxidase iron-sulfur subunit. Homology to glcF of E. coli of 56% (sprot|GLCF_ECOLI) Pfam: Domain of unknown function (DUF224) (192-256 aa; 329-391 aa) no signal peptide no TMHs; High confidence in function and specificity.
     
 0.881
glcE
Probable glycolate oxidase subunit GlcE. Homology to glcE of E. coli of 47% (sprot|GLCE_ECOLI) InterPro: FAD linked oxidase N-terminal (IPR006093) Pfam: FAD binding domain Tigrfam: glcD: glycolate oxidase subunit GlcD no singla peptide no TMHs; High confidence in function and specificity.
    
 0.857
azo0826
Glycerate dehydrogenase (EC 1.1.1.29) (NADH-dependent hydroxypyruvate reductase) (HPR) (GDH) (Hydroxypyruvate dehydrogenase) (Glyoxylate reductase) (HPR-A). PLAYS A CENTRAL ROLE IN ASSIMILATION OF CARBON. IT CONVERTS HYDROXYPYRUVATE TO GLYCERATE AS A KEY STEP IN THE SERINE CYCLE AND MAY ALSO PLAY AN IMPORTANT ROLE IN C2 REACTIONS BY INTERCONVERTING GLYOXYLATE AND GLYCOLATE; Specificity unclear.
 
  
 0.827
guaB
IMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
  
 
 0.691
pheA
Bifunctional chorismate mutase/prephenate dehydratase P-protein, pheA,; High confidence in function and specificity.
  
 
 0.675
azo3328
General secretion pathway protein E,; Specificity unclear.
   
   0.635
azo2617
TREMBL:Q89L44: 48% identity.64% similarity. probable haloacid dehalogenase-like hydrolase. InterPro:IPR005834; Hydrolase. Pfam:PF00702; Hydrolase; Phosphoglycolate phosphatase(PGP). TIGR00099: conserved hypothetical prot; Function unclear.
  
  
  0.627
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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