STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
azo3329Putative 3',5'-cyclic-nucleotide phosphodiesterase; Probable 35-cyclic-nucleotide phosphodiesterase precursor (EC 3.1.4.17) (PDEase) (3:5-CNP). TREMBL:Q8ZD92:28% identity, 47% similarity InterPro; IPR001279; Blactmase-like. IPR000396; Pdiesterase2. Pfam: PF00753; Lactamase_B No transmembrane helices TIGR00010: deoxyribonuclease TatD fami; Function unclear. (232 aa)    
Predicted Functional Partners:
azo3330
FHA-domain containing protein; Conserved hypothetical protein which may be involved into signal transduction processes. Important Domain: Pfam:PF00498 FHA domain. The forkhead-associated (FHA) domain is a phosphopeptide recognition domain found in many regulatory proteins. It displays specificity for phosphothreonine-containing epitopes but will also recognise phosphotyrosine with relatively high affinity. The domain is present in a diverse range of proteins, such as kinases, phosphatases, kinesins, transcription factors,RNA-binding proteins and metabolic enzymes.
 
     0.796
azo1660
Conserved hypothetical protein; Possible aldose 1-epimerase.Aldose 1-epimerase (mutarotase), responsible for the anomeric interconversion of D-glucose and other aldoses between their alpha- and beta-forms. InterPro:IPR008183; Ald1_epimerase. Pfam:PF01263; Aldose_epim; 1; Belongs to the glucose-6-phosphate 1-epimerase family.
  
 
   0.781
azo0631
HD-domain containing protein.
 
   0.736
azo1058
Conserved hypothetical secreted proteins. Homology to of Dechloromonas aromatica of 56% (gi|41723709|ref|ZP_00150619.1|(NBCI ENTREZ)). Signal Peptide Present. No TMH present. Has PF03734:(IPR005490)ErfK/YbiS/YcfS/YnhG;This family of proteins are found in a range of bacteria. The conserved region contains a conserved histidine and cysteine,suggesting that these proteins have an enzymatic activity. Several members of this family contain peptidoglycan binding domains. So these proteins may use peptidoglycan or a precursor as a substrate; Conserved hypothetical protein.
  
     0.698
azo3328
General secretion pathway protein E,; Specificity unclear.
 
     0.697
azo1059
Conserved hypothetical secreted protein. Homology to Daro03002816 of Dechloromonas aromatica of 42% (gi|53730051|ref|ZP_00348646.1|(NBCI ENTREZ)). domain structure: 59 aa - 92 aa TRP; 93 aa- 126 aa TRP; 127 aa -155 aa TRP. InterPro: TPR repeat (IPR001440); Type I antifreeze protein (IPR000104). Pfam: TRP Domain. signal peptide. no TMHs; Conserved hypothetical protein.
  
 
   0.661
pppL
Putative phosphoprotein phosphatase,; Family membership.
 
     0.513
rpe
Ribulose-phosphate 3-epimerase(also known as pentose-5-phosphate 3-epimerase, PPE or Rpe), is the enzyme that converts D-ribulose 5-phosphate into D-xylulose 5-phosphate in Calvin's reductive pentose phosphate cycle. 71%Ribul_P_3_epim. Pfam:PF00834; Ribul_P_3_epim; 1. TIGRFAMs:TIGR01163; rpe; 1; High confidence in function and specificity.
       0.497
azo0628
Putative adenylate/guanylate cyclase,; Conserved hypothetical protein.
 
   
 0.487
azo1256
Putative serin/threonine protein kinase, only very low similarity to SWISSPROT: sprot|PKSC_STRCO (13% Streptomyces coelicolor, serine/threonine protein kinase PksC (EC 2.7.11.1)) / TREMBL: trembl|Q9S478 (13% Myxococcus xanthus, Pkn4). Pfam: PF00069 Pkinase. SMART:SM00221 STYKc (Protein kinase; unclassified specificity). SM00065 GAF (Domain present in phytochromes and cGMP-specific phosphodiesterases); Family membership.
 
     0.466
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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