node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
gltA | gltB | azo1554 | azo3642 | Probable citrate synthase. Homology to gltA of s. meliloti of 69% (sprot|CISY_RHIME). Citrate synthase is a member of a small family of enzymes that can directly form a carbon-carbon bond without the presence of metal ion cofactors. It catalyses the first reaction in the Krebs' cycle: Citrate + CoA = acetyl-CoA + H2 O + oxaloacetate InterPro: Citrate synthase (IPR002020) Pfam: Citrate synthase no signal peptide no TMHs; High confidence in function and specificity. | Ferredoxin-dependent glutamate synthase,; Specificity unclear. | 0.965 |
gltA | lpdA | azo1554 | azo1371 | Probable citrate synthase. Homology to gltA of s. meliloti of 69% (sprot|CISY_RHIME). Citrate synthase is a member of a small family of enzymes that can directly form a carbon-carbon bond without the presence of metal ion cofactors. It catalyses the first reaction in the Krebs' cycle: Citrate + CoA = acetyl-CoA + H2 O + oxaloacetate InterPro: Citrate synthase (IPR002020) Pfam: Citrate synthase no signal peptide no TMHs; High confidence in function and specificity. | Dihydrolipoamide dehydrogenase. Homology to lpdA of N. meningitides of 70% (trembl|Q59099). THE BRANCHED-CHAIN ALPHA-KETO DEHYDROGENASE COMPLEX CATALYZES THE OVERALL CONVERSION OF ALPHA-KETO ACIDS TO ACYL-COA AND CO(2). IT CONTAINS MULTIPLE COPIES OF 3 ENZYMATIC COMPONENTS: BRANCHED-CHAIN ALPHA-KETO ACID DECARBOXYLASE (E1) LIPOAMIDE ACYLTRANSFERASE (E2) AND LIPOAMIDE DEHYDROGENASE (E3) (BY SIMILARITY). InterPro: FAD-dependent pyridine nucleotide-disulphide oxidoreductase (IPR001327); Pyridine nucleotide-disulphide oxidoreductase, classI (IPR001100); biotin/Lipoyl attachment (IPR000089) [...] | 0.971 |
gltA | odhA | azo1554 | azo1555 | Probable citrate synthase. Homology to gltA of s. meliloti of 69% (sprot|CISY_RHIME). Citrate synthase is a member of a small family of enzymes that can directly form a carbon-carbon bond without the presence of metal ion cofactors. It catalyses the first reaction in the Krebs' cycle: Citrate + CoA = acetyl-CoA + H2 O + oxaloacetate InterPro: Citrate synthase (IPR002020) Pfam: Citrate synthase no signal peptide no TMHs; High confidence in function and specificity. | Probable 2-oxoglutarate dehydrogenase. Homology to odhA of A. eutrophus of 63% (sprot|ODO1_ALCEU). THE 2-OXOGLUTARATE DEHYDROGENASE COMPLEX CATALYZES THE OVERALL CONVERSION OF 2-OXOGLUTARATE TO SUCCINYL-COA & CO(2). IT CONTAINS MULTIPLE COPIES OF 3 ENZYMATIC COMPONENTS: 2-OXOGLUTARATE DEHYDROGENASE (E1) DIHYDROLIPOAMIDE SUCCINYLTRANSFERASE (E2) AND LIPOAMIDE DEHYDROGENASE (E3). InterPro: Dehydrogenase E1 component (IPR001017); Transletolase (IPR005474) Tigrfam: 2oxo_dh_E1: 2-oxoglutarate dehydrogenase, E1 component Pfam: Dehydrogenase E1 component, Transketolas, pyridine binding domain [...] | 0.960 |
gltA | odhB | azo1554 | azo1556 | Probable citrate synthase. Homology to gltA of s. meliloti of 69% (sprot|CISY_RHIME). Citrate synthase is a member of a small family of enzymes that can directly form a carbon-carbon bond without the presence of metal ion cofactors. It catalyses the first reaction in the Krebs' cycle: Citrate + CoA = acetyl-CoA + H2 O + oxaloacetate InterPro: Citrate synthase (IPR002020) Pfam: Citrate synthase no signal peptide no TMHs; High confidence in function and specificity. | Dihydrolipoamide S-succinyltransferase; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). | 0.917 |
gltA | sdhA | azo1554 | azo1551 | Probable citrate synthase. Homology to gltA of s. meliloti of 69% (sprot|CISY_RHIME). Citrate synthase is a member of a small family of enzymes that can directly form a carbon-carbon bond without the presence of metal ion cofactors. It catalyses the first reaction in the Krebs' cycle: Citrate + CoA = acetyl-CoA + H2 O + oxaloacetate InterPro: Citrate synthase (IPR002020) Pfam: Citrate synthase no signal peptide no TMHs; High confidence in function and specificity. | Probable succinate dehydrogenase, flavoprotein subunit. Homology to sdhA of C. burnetii of 54% (sprot|DHSA_COXBU) Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein,cytochrome b-556 and a hydrophobic protein. CATALYTIC ACTIVITY: Succinate + acceptor = fumarate + reduced acceptor. InterPro: Fumarate reductase/succinate dehydrogenase flavoprotein N-terminal (IPR003953); Fumarate reductase/succinate dehydrogenase FAD-binding site (IPR003952); Fumarate reductase/succinate dehydrogenase, C-terminal (IPR004112) Pfam: FAD-binding domain; Fumarate reduct [...] | 0.981 |
gltA | sdhB | azo1554 | azo1552 | Probable citrate synthase. Homology to gltA of s. meliloti of 69% (sprot|CISY_RHIME). Citrate synthase is a member of a small family of enzymes that can directly form a carbon-carbon bond without the presence of metal ion cofactors. It catalyses the first reaction in the Krebs' cycle: Citrate + CoA = acetyl-CoA + H2 O + oxaloacetate InterPro: Citrate synthase (IPR002020) Pfam: Citrate synthase no signal peptide no TMHs; High confidence in function and specificity. | Succinate dehydrogenase, iron-sulfur subunit. Homology to sdhB of C. burnetii of 59% (sprot|DHSB_COXBU). InterPro: Succinate dehydrogenase/fumarate reductase iron-sulfur protein (IPR004489); 4fe-4S ferredoxin, iron-sulfur binding domain (IPR001450); Ferredoxin (IPR1041) Pfam: 2Fe-2S iron-sulfur cluster binding domain Tigrfam: dhsB: succinate dehydrogenase and fumarat reductase iron-sulfur protein no TMHs; High confidence in function and specificity. | 0.983 |
gltA | sdhC | azo1554 | azo1549 | Probable citrate synthase. Homology to gltA of s. meliloti of 69% (sprot|CISY_RHIME). Citrate synthase is a member of a small family of enzymes that can directly form a carbon-carbon bond without the presence of metal ion cofactors. It catalyses the first reaction in the Krebs' cycle: Citrate + CoA = acetyl-CoA + H2 O + oxaloacetate InterPro: Citrate synthase (IPR002020) Pfam: Citrate synthase no signal peptide no TMHs; High confidence in function and specificity. | Succinate dehydrogenase cytochrome b-556 subunit,sdhC.58% Identity to TrEMBL;Q7NZ57.52% to TrEMBL;Q9JRJ0,36% to SwissProt;P10446. Has PF01127,Succinate dehydrogenase cytochrome b subunit;IPR000701 Sdh_cyt; Succinate dehydrogenase (SDH) is a membrane-bound complex of two main components: a membrane-extrinsic component composed of an FAD-binding flavoprotein and an iron-sulphur protein, and a hydrophobic component composed of a cytochrome b and a membrane anchor protein.The cytochrome b component is a mono heme transmembrane protein belonging to a family that includes cytochrome b-556 fr [...] | 0.906 |
gltA | sdhD | azo1554 | azo1550 | Probable citrate synthase. Homology to gltA of s. meliloti of 69% (sprot|CISY_RHIME). Citrate synthase is a member of a small family of enzymes that can directly form a carbon-carbon bond without the presence of metal ion cofactors. It catalyses the first reaction in the Krebs' cycle: Citrate + CoA = acetyl-CoA + H2 O + oxaloacetate InterPro: Citrate synthase (IPR002020) Pfam: Citrate synthase no signal peptide no TMHs; High confidence in function and specificity. | Succinate dehydrogenase, hydrophobic membrane anchor subunit. Homology to sdhD of C. burnetii of 41% (sprot|DHSD_COXBU). THIS IS THE HYDROPHOBIC COMPONENT OF THE SUCCINATE DEHYDROGENASE COMPLEX. IT IS SUGGESTED THAT IT IS REQUIRED TO ANCHOR THE CATALYTIC COMPONENTS TO THE CYTOPLASMIC MEMBRANE. no signal peptide 3 TMHS; Family membership. | 0.820 |
gltA | sucC | azo1554 | azo3333 | Probable citrate synthase. Homology to gltA of s. meliloti of 69% (sprot|CISY_RHIME). Citrate synthase is a member of a small family of enzymes that can directly form a carbon-carbon bond without the presence of metal ion cofactors. It catalyses the first reaction in the Krebs' cycle: Citrate + CoA = acetyl-CoA + H2 O + oxaloacetate InterPro: Citrate synthase (IPR002020) Pfam: Citrate synthase no signal peptide no TMHs; High confidence in function and specificity. | Probable succinyl-CoA synthetase, beta chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.991 |
gltA | sucD | azo1554 | azo3332 | Probable citrate synthase. Homology to gltA of s. meliloti of 69% (sprot|CISY_RHIME). Citrate synthase is a member of a small family of enzymes that can directly form a carbon-carbon bond without the presence of metal ion cofactors. It catalyses the first reaction in the Krebs' cycle: Citrate + CoA = acetyl-CoA + H2 O + oxaloacetate InterPro: Citrate synthase (IPR002020) Pfam: Citrate synthase no signal peptide no TMHs; High confidence in function and specificity. | Probable succinyl-CoA synthetase, alpha chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.913 |
gltB | gltA | azo3642 | azo1554 | Ferredoxin-dependent glutamate synthase,; Specificity unclear. | Probable citrate synthase. Homology to gltA of s. meliloti of 69% (sprot|CISY_RHIME). Citrate synthase is a member of a small family of enzymes that can directly form a carbon-carbon bond without the presence of metal ion cofactors. It catalyses the first reaction in the Krebs' cycle: Citrate + CoA = acetyl-CoA + H2 O + oxaloacetate InterPro: Citrate synthase (IPR002020) Pfam: Citrate synthase no signal peptide no TMHs; High confidence in function and specificity. | 0.965 |
gltB | lpdA | azo3642 | azo1371 | Ferredoxin-dependent glutamate synthase,; Specificity unclear. | Dihydrolipoamide dehydrogenase. Homology to lpdA of N. meningitides of 70% (trembl|Q59099). THE BRANCHED-CHAIN ALPHA-KETO DEHYDROGENASE COMPLEX CATALYZES THE OVERALL CONVERSION OF ALPHA-KETO ACIDS TO ACYL-COA AND CO(2). IT CONTAINS MULTIPLE COPIES OF 3 ENZYMATIC COMPONENTS: BRANCHED-CHAIN ALPHA-KETO ACID DECARBOXYLASE (E1) LIPOAMIDE ACYLTRANSFERASE (E2) AND LIPOAMIDE DEHYDROGENASE (E3) (BY SIMILARITY). InterPro: FAD-dependent pyridine nucleotide-disulphide oxidoreductase (IPR001327); Pyridine nucleotide-disulphide oxidoreductase, classI (IPR001100); biotin/Lipoyl attachment (IPR000089) [...] | 0.965 |
gltB | odhA | azo3642 | azo1555 | Ferredoxin-dependent glutamate synthase,; Specificity unclear. | Probable 2-oxoglutarate dehydrogenase. Homology to odhA of A. eutrophus of 63% (sprot|ODO1_ALCEU). THE 2-OXOGLUTARATE DEHYDROGENASE COMPLEX CATALYZES THE OVERALL CONVERSION OF 2-OXOGLUTARATE TO SUCCINYL-COA & CO(2). IT CONTAINS MULTIPLE COPIES OF 3 ENZYMATIC COMPONENTS: 2-OXOGLUTARATE DEHYDROGENASE (E1) DIHYDROLIPOAMIDE SUCCINYLTRANSFERASE (E2) AND LIPOAMIDE DEHYDROGENASE (E3). InterPro: Dehydrogenase E1 component (IPR001017); Transletolase (IPR005474) Tigrfam: 2oxo_dh_E1: 2-oxoglutarate dehydrogenase, E1 component Pfam: Dehydrogenase E1 component, Transketolas, pyridine binding domain [...] | 0.961 |
gltB | odhB | azo3642 | azo1556 | Ferredoxin-dependent glutamate synthase,; Specificity unclear. | Dihydrolipoamide S-succinyltransferase; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). | 0.794 |
gltB | sdhA | azo3642 | azo1551 | Ferredoxin-dependent glutamate synthase,; Specificity unclear. | Probable succinate dehydrogenase, flavoprotein subunit. Homology to sdhA of C. burnetii of 54% (sprot|DHSA_COXBU) Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein,cytochrome b-556 and a hydrophobic protein. CATALYTIC ACTIVITY: Succinate + acceptor = fumarate + reduced acceptor. InterPro: Fumarate reductase/succinate dehydrogenase flavoprotein N-terminal (IPR003953); Fumarate reductase/succinate dehydrogenase FAD-binding site (IPR003952); Fumarate reductase/succinate dehydrogenase, C-terminal (IPR004112) Pfam: FAD-binding domain; Fumarate reduct [...] | 0.479 |
gltB | sdhC | azo3642 | azo1549 | Ferredoxin-dependent glutamate synthase,; Specificity unclear. | Succinate dehydrogenase cytochrome b-556 subunit,sdhC.58% Identity to TrEMBL;Q7NZ57.52% to TrEMBL;Q9JRJ0,36% to SwissProt;P10446. Has PF01127,Succinate dehydrogenase cytochrome b subunit;IPR000701 Sdh_cyt; Succinate dehydrogenase (SDH) is a membrane-bound complex of two main components: a membrane-extrinsic component composed of an FAD-binding flavoprotein and an iron-sulphur protein, and a hydrophobic component composed of a cytochrome b and a membrane anchor protein.The cytochrome b component is a mono heme transmembrane protein belonging to a family that includes cytochrome b-556 fr [...] | 0.446 |
gltB | sdhD | azo3642 | azo1550 | Ferredoxin-dependent glutamate synthase,; Specificity unclear. | Succinate dehydrogenase, hydrophobic membrane anchor subunit. Homology to sdhD of C. burnetii of 41% (sprot|DHSD_COXBU). THIS IS THE HYDROPHOBIC COMPONENT OF THE SUCCINATE DEHYDROGENASE COMPLEX. IT IS SUGGESTED THAT IT IS REQUIRED TO ANCHOR THE CATALYTIC COMPONENTS TO THE CYTOPLASMIC MEMBRANE. no signal peptide 3 TMHS; Family membership. | 0.420 |
gltB | sucC | azo3642 | azo3333 | Ferredoxin-dependent glutamate synthase,; Specificity unclear. | Probable succinyl-CoA synthetase, beta chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.961 |
gltB | sucD | azo3642 | azo3332 | Ferredoxin-dependent glutamate synthase,; Specificity unclear. | Probable succinyl-CoA synthetase, alpha chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.965 |
lpdA | gltA | azo1371 | azo1554 | Dihydrolipoamide dehydrogenase. Homology to lpdA of N. meningitides of 70% (trembl|Q59099). THE BRANCHED-CHAIN ALPHA-KETO DEHYDROGENASE COMPLEX CATALYZES THE OVERALL CONVERSION OF ALPHA-KETO ACIDS TO ACYL-COA AND CO(2). IT CONTAINS MULTIPLE COPIES OF 3 ENZYMATIC COMPONENTS: BRANCHED-CHAIN ALPHA-KETO ACID DECARBOXYLASE (E1) LIPOAMIDE ACYLTRANSFERASE (E2) AND LIPOAMIDE DEHYDROGENASE (E3) (BY SIMILARITY). InterPro: FAD-dependent pyridine nucleotide-disulphide oxidoreductase (IPR001327); Pyridine nucleotide-disulphide oxidoreductase, classI (IPR001100); biotin/Lipoyl attachment (IPR000089) [...] | Probable citrate synthase. Homology to gltA of s. meliloti of 69% (sprot|CISY_RHIME). Citrate synthase is a member of a small family of enzymes that can directly form a carbon-carbon bond without the presence of metal ion cofactors. It catalyses the first reaction in the Krebs' cycle: Citrate + CoA = acetyl-CoA + H2 O + oxaloacetate InterPro: Citrate synthase (IPR002020) Pfam: Citrate synthase no signal peptide no TMHs; High confidence in function and specificity. | 0.971 |