STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
azo3336Conserved hypothetical protein,ybgI, 48% identity(67% similarity) to SwissProt;P75743(E.coli)SP|Q8XFW7. SwissProt;Q8XVA0(58% identity)Ralstonia solanacearum. TrEMBL;Q82UH6(53% identity)Nitrosomonas europaea. Has PF01784, NIF3 (NGG1p interacting factor 3);IPR002678, DUF34; This family contains several NIF3 (NGG1p interacting factor 3) protein homologues. NIF3 interacts with the yeast transcriptional coactivator NGG1p which is part of the ADA complex, the exact function of this interaction is unknown. (251 aa)    
Predicted Functional Partners:
ribAB
GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family.
    
  0.660
algW
Probable serine protease AlgW. Homology to algW of P. aeruginosa of 48% (trembl|Q51374). InterPro: Serine proteases trypsin family (IPR001254); PDZ domain (Also known as DHR or GLGF) (IPR001478); HtrA/DegQ protease family (IPR001940) Pfam: PDZ domain (Also known as DHR or GLGF); Trypsin no signal peptide 1 TMH; High confidence in function and specificity; Belongs to the peptidase S1C family.
  
    0.623
folE
FolE protein; GTP cyclohydrolase I (EC 3.5.4.16) (GTP-CH-I). folE: GTP cyclohydrolase I; High confidence in function and specificity.
    
 0.573
rmlB
dTDP-glucose 46-dehydratase (EC 4.2.1.46). InterPro: NAD dependent epimerase/dehydratase family; High confidence in function and specificity; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.
  
    0.565
pepD
Probable aminoacyl-histidine dipeptidase (EC 3.4.13.3) (Xaa-His dipeptidase) (X-His dipeptidase) (Beta-alanyl-histidine dipeptidase) (Carnosinase) (Peptidase D). Homology to pepD of E. coli of 44%. THIS DIPEPTIDASE HAS SPECIFICITY FOR THE UNUSUAL DIPEPTIDE BETA-ALANYL-L-HISTIDINE. InterPro: Peptidase family M20/M25/M40 (IPR002933) Pfam: Peptidase family M20/M25/M40 no signal peptide no TMHs; High confidence in function and specificity.
  
    0.559
metG
MetG protein; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
 
  
 0.557
ndk
Nucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
   
  0.555
pykA
Pyruvate kinase (PK) catalyses the final step in glycolysis, the conversion of phosphoenolpyruvate to pyruvate with concomitant phosphorylation of ADP to ATP:ADP + phosphoenolpyruvate = ATP + pyruvate. 52% Pyruvate_kinase. Pfam:PF00224; PK; 1.PF02887; PK_C; 1. TIGRFAMs:TIGR01064; pyruv_kin; 1; High confidence in function and specificity.
   
 0.555
folK
2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase (7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase) (HPPK) (6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase) (PPPK). InterPro: 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase Pfam:7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase; High confidence in function and specificity.
    
  0.514
folE2
Conserved hypothetical protein; Converts GTP to 7,8-dihydroneopterin triphosphate.
    
  0.504
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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