STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pilBType IV pilus assembly protein; PilB encodes for a 14.2 kDa polypeptide showing similarity to FimF, a component of type I fimbriae of E. coli. It may be part of the pilus assembly complex or the pilus itself. (Reference: Doerr et al., 1998 Molecular Microbiology); Specificity unclear. (142 aa)    
Predicted Functional Partners:
pilA
Tfp structural protein; PilA encodes an unusually short (6.4 kDa)putative pilin precursor showing 100% sequence identity to the conserved N-terminus of the Pseudomonas aeruginosa type IV pilin. (Reference: Doerr et al., 1998 Molecular Microbiology); High confidence in function and specificity.
       0.578
azo3351
ATP-binding cassette (ABC) transporters form a large family of proteins responsible for translocation of a variety of compounds across biological membranes. They are composed of two transmembrane domains responsible for binding and transport and two nucleotide-binding domains responsible for coupling the energy of ATP hydrolysis to conformational changes in the TMDs, TREMBL:O59091 (37% identity); TREMBL:Q7NDM5 (40% identity). Pfam (PF00005): ABC transporter. TC (3.A.1): The ATP-binding Cassette (ABC) Superfamily; High confidence in function and specificity.
       0.467
azo3352
Similar to hypothetical protein GSU1500 of Geobacter sulfurreducens PCA (16%). TMHMM2 reporting one TMhelix. Sigcleave reporting one SignalPeptide. Coils2 reporting coiled coil region.
       0.467
azo3353
Conserved hypothetical membrane protein; In Myxococcus xanthus pilI are co-transcribed with pilH an ABC transporter homologue required for type IV pilus biogenesis and social gliding. pilI appear to be functionally related to pilH. Similar to membrane protein of Geobacter sulfurreducens PCA (14%) and weak; Conserved hypothetical protein.
       0.467
ampD2
N-acetyl-anhydromuramyl-L-alanine amidase; Putative signaling protein in beta-lactamase regulation. AMPD seems not to act as a direct sensor for beta-lactams. It hydrolyzes 16-anhydro-N-acetylmuramoyl-L-alanyl-D-3glutamyl-meso- diaminopimelic acid to the tripeptide L-alanyl-gamma-D-glutamyl- meso-diaminopimelate (By similarity), TREMBL:Q8KRJ4 (63% identity); SWISSPROT:P82974 (60% identity). Pfam (PF01510): N-acetylmuramoyl-L-alanine amidase; High confidence in function and specificity.
       0.464
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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