STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pilATfp structural protein; PilA encodes an unusually short (6.4 kDa)putative pilin precursor showing 100% sequence identity to the conserved N-terminus of the Pseudomonas aeruginosa type IV pilin. (Reference: Doerr et al., 1998 Molecular Microbiology); High confidence in function and specificity. (59 aa)    
Predicted Functional Partners:
pilC
Type 4 pilus biogenesis protein; Pilus assembly protein PilC is a component of the pilus biogenesis apparatus, similarity to pir|B35384 (50%). This apparatus is responsible for the stabilization, translocation and assembly of the monomeric pilin subunits into the pilus organelle. InterPro (IPR001992): Bacterial type II secretion system protein. InterPro (IPR003004): Bacterial general secretion pathway protein F Pfam (PF00482): Bacterial type II secretion system protein TMHMM reporting three TMH; High confidence in function and specificity.
 
  
 0.801
azo2180
Conserved hypothetical prepilin like protein; In P. aeruginosa PilE is probable involved in pilus biogenesis and in twitching motility. Similarity to PilE of Ralstonia eutropha (33%) TMHMM reporting one TMhelix. Pfam: pilin domain; Conserved hypothetical protein.
 
  
 0.752
pilM
Type 4 fimbrial biogenesis protein PilM, similarity to trembl|Q82SK1 (56%)and to pir|S77726 (47%). Four genes,pilM-P, encode the necessary proteins and pilM is required for the assembly of the type IV fimbriae in Pseudomonas aeruginosa; Specificity unclear.
 
   
 0.746
pilB2
Pilus assembly protein PilB is a component of the pilus biogenesis apparatus,; High confidence in function and specificity.
 
 0.699
pilD
Prepilin peptidase; Cleaves type-4 fimbrial leader sequence and methylates the N- terminal (generally Phe) residue.
 
  
 0.679
pilO
Type 4 fimbrial biogenesis protein PilO, similarity to pir|S77728 (40%). PilO proteins are involved in the assembly of pilin. TMHMM reporting one TMH; Specificity unclear.
 
   
 0.665
azo3328
General secretion pathway protein E,; Specificity unclear.
 
 0.664
gspE3
General secretion pathway protein E,; Specificity unclear.
 
 0.656
gspF2
General secretion pathway protein F,similar trembl|Q88HD6 (39%). The general (type II) secretion pathway (GSP) within Gram-negative bacteria is a signal sequence-dependent process responsible for protein export. The process has two stages: exoproteins are first translocated across the inner membrane by the general signal-dependent export pathway (GEP), and then across the outer membrane by a species-specific accessory mechanism. InterPro (IPR001992): Bacterial type II secretion system protein. InterPro (IPR003004): Bacterial general secretion pathway protein F Pfam (PF00482): Bacterial [...]
 
  
 0.642
gspF1
General secretion pathway protein F; Type II secretory pathway component F,; Specificity unclear.
 
  
 0.639
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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