STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pilSTwo component system sensor protein,; High confidence in function and specificity. (517 aa)    
Predicted Functional Partners:
pilR
Two component system response regulator,; High confidence in function and specificity.
 
 0.982
azo3381
Hypothetical signaling protein.
  
 0.936
azo1817
Conserved hypothetical two-component hybrid sensor and regulator. Homology to ebA6890 of Azoarcus sp. EbN1 of 56% (gnl|keqq|eba:ebA6890(KEGG)). InterPro: IPR003594 ATPbind_ATPase. IPR004358 Bact_sens_pr_C. IPR005467 His_kinase. IPR003661 His_kinA_N. IPR009082 His_kin_homodim. IPR001610 PAC. IPR000700 PAS-assoc_C. IPR000014 PAS_domain. IPR001789 Response_reg. Pfam: PF02518 HATPase_c. PF00512 HisKA. PF00785 PAC. PF00989 PAS. PF00072 Response_reg. SMART: SM00387 HATPase_c. SM00388 HisKA. SM00086 PAC. SM00091 PAS. SM00448 REC. TIGRFAM: TIGR00229 sensory_box; 3 TMHMM reporting 7 transmembra [...]
 
 
0.906
vsrB
Putative virulence regulator protein,ATPbind_ATPase. IPR005467; His_kinase. IPR003661; His_kinA_N. IPR003660; HAMP. IPR001789; Response_reg. Pfam: PF02518; HATPase_c. PF00512; HisKA. PF00672; HAMP. PF00072; Response_reg. SMART: SM00387; HATPase_c. SM00388; HisKA. SM00304; HAMP. SM00448; REC. Signal P reporting signal peptide. TMHMM reporting 2 transmembrane helices; Specificity unclear.
 
 0.884
azo2450
Putative two-component system sensor protein,; Function unclear.
 
 
0.861
azo2457
Putative sensory box histidine kinase,; Function unclear.
 
 
 0.861
azo2362
Putative sensor kinase/response regulator hybrid protein,; Specificity unclear.
 
 
 0.829
ntrX
Probable nitrogen assimilation regulatory protein,; High confidence in function and specificity.
 
 0.823
azo3358
Hypothetical membrane protein. No real homology of the entire protein to the data bank. no domains predicted no signal peptide 1TMH.
       0.811
pilG
Pilus protein, Response_reg. Pfam: PF00072; Response_reg. SMART: SM00448; REC. PilG protein. IS INVOLVED IN PILUS BIOSYNTHESIS AND TWITCHING MOTILITY. MAY ACT AS A SINGLE-DOMAIN RESPONSE REGULATOR WHOSE FUNCTION MAY BE TO RECEIVE A CERTAIN ENVIRONMENTAL SIGNAL(S) AND THEN TRANSDUCE THAT SIGNAL TO THE PILUS ASSEMBLY MACHINERY VIA SPECIFIC PROTEIN-PROTEIN INTERACTIONS; High confidence in function and specificity.
  
 
 0.805
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.