STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
azo3358Hypothetical membrane protein. No real homology of the entire protein to the data bank. no domains predicted no signal peptide 1TMH. (113 aa)    
Predicted Functional Partners:
pilR
Two component system response regulator,; High confidence in function and specificity.
       0.811
pilS
Two component system sensor protein,; High confidence in function and specificity.
       0.811
azo1221
Conserved hypothetical aromatic/alkene monooxygenase, subunit beta Homology to blr3679 of B. japonicum of 53% (trembl|Q89P04(SRS) Bacterial aromatic/alkene monooxygenase is a multicomponent enzyme that catabolises phenol and some of its methylated derivatives (like methane and toulene). Interpro: Methane/Penol/Toluene hydroxylase (IPR003430) Pfam: Methane/Penol/Toluene hydroxylase (PF02332) no signal peptide no TMHs; Specificity unclear.
   
 0.791
lapL
Phenol hydroxylase p1 protein. Catabolizes phenol and some of its methylated derivates. P1 is required for growth on phenol and for in vitro phenol hydroxylase activity. Similar to SWISSPROT: sprot|DMPL_PSESP (52% Pseudomonas sp. (strain CF600), DmpL) / TREMBL: trembl|Q7WYF3 (67% Pseudomonas sp. KL28, LapL) InterPro: IPR003430 Phenol_Hydrox. Pfam: PF02332 Methane/Phenol/Toluene Hydroxylase. Part of the lap operon: In Pseudomonas sp. strain KL28 the genes,designated as lap (for long-chain alkylphenols), encoding enzymes for the catabolic 3- and 4-alkylphenol degradation pathway. The lap [...]
   
 0.791
poxB
Probable Phenol hydroxylase, subunit P1,65% identity(69% similarity) to TrEMBL;Q7WYF3 LapL [lapL] [Pseudomonas sp. KL28]. Has PF02332;Methane/Phenol/Toluene Hydroxylase domain;IPR003430: Bacterial phenol hydroxylase (EC: 1.14.13.7) is a multicomponent enzyme that catabolises phenol and some of its methylated derivatives. This family contains both the P1 and P3 polypeptides of phenol hydroxlase and the alpha and beta chain of methane hydroxylase protein A. Methane hydroxylase protein A (EC: 1.14.13.25) is responsible for the initial oxygenation of methane to methanol in methanotrophs. I [...]
   
 0.791
lapM
Phenol 2-monooxygenase p2 component,; High confidence in function and specificity.
   
  0.714
lapO
Phenol 2-monooxygenase p4 component,; High confidence in function and specificity.
   
  0.714
poxE
Probable phenol hydroxylase, subunit P4; Pseudomonas sp. phenol hydroxylase P4 protein (EC 1.14.13.7, (phenol 2-monooxygenase P4 component). CATABOLIZES PHENOL AND SOME OF ITS METHYLATED DERIVATIVES. P4 IS REQUIRED FOR GROWTH ON PHENOL AND FOR IN VITRO PHENOL HYDROXYLASE ACTIVITY; High confidence in function and specificity.
   
  0.714
poxC
Probable phenol hydrolase, subunit P2. Catabolizes phenol and some of its methylated derivatives. p2 is required for growth on phenol, and for in vitro phenol hydroxylase activity. Similar to SWISSPROT:P19731 (47% similarity,71% identity). Pfam (PF02406): MmoB/DmpM family; High confidence in function and specificity.
   
  0.714
ybdL
Aminotransferases share certain mechanistic features with other pyridoxal-phosphate dependent enzymes,such as the covalent binding of the pyridoxal-phosphate group to a lysine residue. On the basis of sequence similarity, these various enzymes can be grouped into subfamilies; these sequences are defined by the aminotransferases class-I pyridoxal-phosphate attachment site signature, which contains the lysine residue involved in pyridoxal-phosphate binding. Similar to trembl|Q8XXV2 (58%) and to sprot|YBDL_ECOLI (52%). Pfam (PF00155): Aminotransferases class-I pyridoxal-phosphate-binding [...]
       0.642
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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