Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
azo3437Conserved hypothetical secreted protein. Homology to ebA3798 of Azoarcus sp. EbN1 of 42% (gnl|keqq|eba:ebA3798(KEGG)). Pfam: DUF534. This is a family of putative secreted proteins of unknown function. signal peptide. no TMHs; Conserved hypothetical protein. (309 aa)    
Predicted Functional Partners:
vsrB
Putative virulence regulator protein,ATPbind_ATPase. IPR005467; His_kinase. IPR003661; His_kinA_N. IPR003660; HAMP. IPR001789; Response_reg. Pfam: PF02518; HATPase_c. PF00512; HisKA. PF00672; HAMP. PF00072; Response_reg. SMART: SM00387; HATPase_c. SM00388; HisKA. SM00304; HAMP. SM00448; REC. Signal P reporting signal peptide. TMHMM reporting 2 transmembrane helices; Specificity unclear.
 
  
  0.850
azo0971
Conserved hypothetical ABC transporter, permease protein. PART OF THE BINDING-PROTEIN-DEPENDENT TRANSPORT SYSTEM. PROBABLY RESPONSIBLE FOR THE TRANSLOCATION OF THE SUBSTRATE ACROSS THE MEMBRANE. InterPro: Binding-system dependent bacterial transporters (araH livH/limM families) (IPR001851) Pfam: Branched-chain amino acid transport system/permease component no signal peptide 8 TMHs 2A78: Carboxylate/Amino Acid/Amine Tran; Specificity unclear.
 
    0.797
aggA
Putative outer membrane efflux protein. Homology to aggA from P. putida of 35%. The OEP family (outer membrane efflux protein) allow export of a variety of substrates in Gram negative bacteria. InterPro: Outer membrane efflux protein Pfam: Outer membrane efflux protein signal peptide no TMHs; Function unclear.
     
  0.686
irgA1
Putative TonB-dependent receptor; 23% TonB_boxC. Pfam:PF00593; TonB_dep_Rec; 1; High confidence in function and specificity.
 
     0.684
hylD
Putative HylD family secretion protein. Homology to hylD of E. coli of 24% (sprot|HLY4_ECOLI) Involved in the transport of hemolysin A. InterPro: HlyD family secretion protein; Gram-negative bacteril RTX secretion protein D Pfam: HylD family secretion protein no signal peptide no TMHs; Family membership.
     
  0.681
azo0835
Membrane fusion protein; The secretion of a number of proteins/molecules require the help of members belonging to the ABC transporter family and a membrane fusion protein belonging to the HlyD family,; Family membership.
     
  0.681
irgA2
Putative TonB-dependent receptor; 24% TonB_boxC. Pfam:PF00593; TonB_dep_Rec; 1. Signal peptide present; High confidence in function and specificity.
 
     0.673
azo2457
Putative sensory box histidine kinase,; Function unclear.
    
  0.662
azo3685
Putative hybrid sensor and regulator protein, MmoS) InterPro: IPR003594; ATPbind_ATPase. IPR005467; His_kinase. IPR003661; His_kinA_N. IPR008207; Hpt. IPR001610; PAC. IPR000700; PAS-assoc_C. IPR000014; PAS_domain. IPR001789; Response_reg. Pfam: PF02518; HATPase_c. PF00512; HisKA. PF00785; PAC. PF00989; PAS. PF00072; Response_reg. SMART: SM00387; HATPase_c. SM00388; HisKA. SM00073; HPT. SM00086; PAC. SM00091; PAS. SM00448; REC. TIGRFAM: TIGR00229; sensory_box. TMHMM reporting 2 transmembrane helices; Family membership.
    
  0.660
barA
Putative sensor-regulator protein,; Specificity unclear.
    
  0.657
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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