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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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[Homology]
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azo3445ABC transporter permease protein; Branched-chain amino acid transport system typically composed of a periplasmic substrate-binding protein, one or two reciprocally homologous integral inner-membrane proteins and one or two peripheral membrane ATP-binding proteins that couple energy to the active transport system.The integral inner-membrane proteins translocate the substrate across the membrane. Similar to trembl|Q881A7 (65%) and to sprot|LIVH_ECOLI (26%). Pfam (PF02653): Binding-system dependent bacterial transporters (araH, livH/limM families) TMHMM reporting eight Tmhelix. SignalP re [...] (308 aa)    
Predicted Functional Partners:
livM4
Putative branched-chain amino acid transport permease. Homology to livM of E. coli of 27%. Part of the binding-protein-dependent transport system for branched-chain amino acids. Probably responsible for the translocation of the substrates across the membrane. Pfam: Branched-chain amino acid transport system no signal peptide probalbe 10 TMHs; Specificity unclear.
 
 0.998
azo3446
ATP-binding cassette (ABC) transporters are multidomain membrane proteins, responsible for the controlled efflux and influx of substances (allocrites) across cellular membranes. ATP-binding protein is for coupling the energy of ATP hydrolysis to conformational changes in the transmembrane domains. Similar to trembl|Q881A6 (55%), to sprot|BRAF_PSEAE (34%) and to sprot|LIVG_ECOLI (33%). Pfam (PF00005): ABC transporter Smart (SM00382): AAA ATPase superfamily ProSite (PS50101): ATP/GTP-binding site motif A (P-loop); Specificity unclear.
 
 
 0.989
livF
ATP-binding cassette (ABC) transporters are multidomain membrane proteins, responsible for the controlled efflux and influx of substances (allocrites) across cellular membranes. ATP-binding protein is for coupling the energy of ATP hydrolysis to conformational changes in the transmembrane domains. Similar to trembl|Q7WQU7 (73%) and to trembl|Q89HM3 (54%). Pfam (PF00005): ABC transporter Smart (SM00382): AAA ATPase superfamily ProSite (PS50101): ATP/GTP-binding site motif A (P-loop); Specificity unclear.
 
 
 0.954
azo3443
Conserved hypothetical ABC-type branched-chain amino acid transport systems, periplasmic component. Homology to Raeut03002728 of R. eutropha of 58% (gi|45519901|ref|ZP_00171452.1|(NCBI ENTREZ)). Pfam: Receptor family ligand binding region. This family includes extracellular ligand binding domains of a wide range of receptors. This family also includes the bacterial amino acid binding proteins of known structure. Signal peptide present. TMH in signal peptide; Family membership.
 
 
 0.947
livG2
ABC transporter ATP-binding protein; Probable high-affinity branched-chain amino acid transport ATP-binding protein BraF. ATP-binding cassette (ABC) transporters are multidomain membrane proteins,responsible for the controlled efflux and influx of substances (allocrites) across cellular membranes. ATP-binding protein is for coupling the energy of ATP hydrolysis to conformational changes in the transmembrane domains. BraF is a COMPONENT OF THE HIGH AFFINITY LEUCINE ISOLEUCINE VALINE TRANSPORT SYSTEM (LIV-I) WHICH IS OPERATIVE WITHOUT NA(+) AND IS SPECIFIC FOR ALANINE AND THREONINE IN AD [...]
 
 
 0.944
livM6
Putative branched-chain amino acid transporter permease. Homology to livM of E. coli of 32%. Part of the binding-protein-dependent transport system for branched-chain amino acids. Probably responsible for the translocation of the substrates across the membrane. InterPro: Binding-system dependent bacterial transporters (araH livH/limM families) Pfam: Branched-chain amino acid transport system. signal peptide probable 10 TMHs; Specificity unclear.
 
 0.931
azo0313
ATP-binding cassette (ABC) transporters are multidomain membrane proteins, responsible for the controlled efflux and influx of substances (allocrites) across cellular membranes. The integral inner-membrane proteins translocate the substrate across the membrane. ATP-binding protein is for coupling the energy of ATP hydrolysis to conformational changes in the transmembrane domains. Similar to trembl|Q8XRX5 (54%) and to trembl|Q8UFI6 (47%). Pfam: ABC transporter Pfam (PF02653): Branched-chain amino acid transport system / permease component Smart : AAA ATPase SignalP reporting Signal pept [...]
 
 
 0.916
azo1992
ATP-binding cassette (ABC) transporters are multidomain membrane proteins, responsible for the controlled efflux and influx of substances (allocrites) across cellular membranes. The integral inner-membrane proteins translocate the substrate across the membrane. ATP-binding protein is for coupling the energy of ATP hydrolysis to conformational changes in the transmembrane domains. Similar to trembl|Q8XRX5 (52%) and to trembl|Q89CG4 (45%). Pfam (PF00005): ABC transporter Pfam (PF02653): Binding-system dependent bacterial transporters (araH, livH/limM families) Smart (SM00382): AAA ATPase [...]
 
 
 0.916
azo2502
Probable branched-chain amino acid ABC transporter,ATP binding protein,; Specificity unclear; Belongs to the binding-protein-dependent transport system permease family.
 
 
 0.916
azo3734
ATP-binding cassette (ABC) transporters are multidomain membrane proteins, responsible for the controlled efflux and influx of substances (allocrites) across cellular membranes. ATP-binding protein is for coupling the energy of ATP hydrolysis to conformational changes in the transmembrane domains. Similar to trembl|Q7NXX0 (58%) and to trembl|Q7VVD3 (59%). Smart: AAA ATPases; Specificity unclear.
 
 
 0.903
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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