STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hemLGlutamate-1-semialdehyde 2,1-aminomutase (GSA) (GSA-AT). TIGRFAM: hemL: glutamate-1-semialdehyde-21-ami; High confidence in function and specificity. (424 aa)    
Predicted Functional Partners:
hemB
Porphobilinogen synthase; Delta-aminolevulinic acid dehydratase chloroplast precursor (ALADH) (ALAD). InterPro: Delta-aminolevulinic acid dehydratase; High confidence in function and specificity; Belongs to the ALAD family.
 
 
 0.995
hemA
HemA protein; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
 
 0.993
cobA2
Uroporphyrin-III C-methyltransferase (Urogen III methylase) (SUMT) (Uroporphyrinogen III methylase) (UROM). TIGRFAM: dph5: diphthine synthase; High confidence in function and specificity; Belongs to the precorrin methyltransferase family.
 
  
 0.969
hemC
Hydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
 
  
 0.942
thiE
Thiamine-phosphate diphosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.
    
 0.849
hemD
HemD protein; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.
 
 
 0.817
cobA1
Uroporphyrin-III C-methyltransferase (EC 2.1.1.107) (Urogen III methylase) (SUMT) (Uroporphyrinogen III methylase) (UROM). CATALYZES BOTH METHYLATIONS AT C-2 AND C-7 OF UROGEN III LEADING TO PRECORRIN-1 AND PRECORRIN-2; THEIR OXIDATIVE ESTERIFICATION GIVES RESPECTIVELY FACTOR I OCTAMETHYL ESTER AND SIROHYDROCHLORIN (BY SIMILARITY). dph5: diphthine synthase; High confidence in function and specificity.
 
  
 0.790
azo2022
Conserved hypotheticalsecreted protein. Homology to bll4707 of B.japonicum of 40% (tremble:Q89L41). No domains predicted. Signal P reporting signal peptide present. No TMH reported to be present; Conserved hypothetical protein.
    
 0.781
azo0262
Hypothetical protein; Similar to TREMBL:Q9PFA7 (61% identity); TREMBL:Q87AD9 (61% identity); SWISSPROT:Q7VKH6 (34% identity); Function unclear; ORF1.
    
 0.719
azo0285
Conserved hypothetical acyl carrier protein. Homology to psptO5093 of P. syringae of 44% (trembl|Q87V48). Interpro: Phosphopanteteine-binding (IPR00613). Pfam: Phosphopantetheine attachment site (PF00550) Phosphopantetheine (or pantetheine 4' phosphate) is the prosthetic group of acyl carrier proteins (ACP) in some multienzyme complexes where it serves as a 'swinging arm' for the attachment of activated fatty acid and amino-acid groups. Tigrfam: acyl_carrier: acyl carrier protein. no signal peptide. no TMHs; Conserved hypothetical protein.
    
 0.719
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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