STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pilGPilus protein, Response_reg. Pfam: PF00072; Response_reg. SMART: SM00448; REC. PilG protein. IS INVOLVED IN PILUS BIOSYNTHESIS AND TWITCHING MOTILITY. MAY ACT AS A SINGLE-DOMAIN RESPONSE REGULATOR WHOSE FUNCTION MAY BE TO RECEIVE A CERTAIN ENVIRONMENTAL SIGNAL(S) AND THEN TRANSDUCE THAT SIGNAL TO THE PILUS ASSEMBLY MACHINERY VIA SPECIFIC PROTEIN-PROTEIN INTERACTIONS; High confidence in function and specificity. (128 aa)    
Predicted Functional Partners:
pilI
Probable pilus biogenesis protein, CheW. Protein pilI. MAY BE A PART OF A SIGNAL-TRANSDUCTION SYSTEM THAT REGULATES TWITCHING MOTILITY BY CONTROLLING PILUS FUNCTION (EXTENSION AND RETRACTION). InterPro: CheW-like domain; High confidence in function and specificity.
 
 
 0.993
pilJ
Probable pilus biogenesis protein,; High confidence in function and specificity.
 
  0.991
azo2457
Putative sensory box histidine kinase,; Function unclear.
 
 0.980
pilL
Putative pilus biogenese protein, ATPbind_ATPase. IPR004358; Bact_sens_pr_C. IPR002545; CheW. IPR004105; H-kinase_dim. IPR005467; His_kinase. IPR008207; Hpt. IPR008208; Hpt_N. IPR001789; Response_reg. Pfam: PF01584; CheW. PF02895; H-kinase_dim. PF02518; HATPase_c. PF01627; Hpt. PF00072; Response_reg. SMART: SM00260; CheW. SM00387; HATPase_c. SM00073; HPT. SM00448; REC. HTH reporting nucleic acid binding motif; Function unclear.
 
0.979
azo3685
Putative hybrid sensor and regulator protein, MmoS) InterPro: IPR003594; ATPbind_ATPase. IPR005467; His_kinase. IPR003661; His_kinA_N. IPR008207; Hpt. IPR001610; PAC. IPR000700; PAS-assoc_C. IPR000014; PAS_domain. IPR001789; Response_reg. Pfam: PF02518; HATPase_c. PF00512; HisKA. PF00785; PAC. PF00989; PAS. PF00072; Response_reg. SMART: SM00387; HATPase_c. SM00388; HisKA. SM00073; HPT. SM00086; PAC. SM00091; PAS. SM00448; REC. TIGRFAM: TIGR00229; sensory_box. TMHMM reporting 2 transmembrane helices; Family membership.
 
0.975
gacS
Putative two-component hybrid sensor and regulator,; Family membership.
 
 0.971
azo2450
Putative two-component system sensor protein,; Function unclear.
 
0.969
barA
Putative sensor-regulator protein,; Specificity unclear.
 
0.965
azo2482
Putative hybrid sensor and regulator; Gene function unknown, no significant homology to proteins of known function. Typical domains for hybrid sensor and regulator are found. InterPro: IPR003594 ATPbind_ATPase. IPR004358 Bact_sens_pr_C. IPR005467 His_kinase. IPR003661 His_kinA_N. IPR001789 Response_reg. IPR008207 Hpt. IPR000014 PAS_domain. IPR001610 PAC. Pfam: PF00072 Response_reg. PF02518 HATPase_c. PF00512 HisKA. PF00989 PAS. PF00785 PAC. SMART: SM00387 HATPase_c. SM00388 HisKA. SM00448 REC. SM00091 PAS SM00086 PAC. TIGRFAM: TIGR00229 PAS domain S-box. Signal P reporting signal pepti [...]
 
0.965
azo2362
Putative sensor kinase/response regulator hybrid protein,; Specificity unclear.
 
 0.953
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.