STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pilIProbable pilus biogenesis protein, CheW. Protein pilI. MAY BE A PART OF A SIGNAL-TRANSDUCTION SYSTEM THAT REGULATES TWITCHING MOTILITY BY CONTROLLING PILUS FUNCTION (EXTENSION AND RETRACTION). InterPro: CheW-like domain; High confidence in function and specificity. (170 aa)    
Predicted Functional Partners:
pilL
Putative pilus biogenese protein, ATPbind_ATPase. IPR004358; Bact_sens_pr_C. IPR002545; CheW. IPR004105; H-kinase_dim. IPR005467; His_kinase. IPR008207; Hpt. IPR008208; Hpt_N. IPR001789; Response_reg. Pfam: PF01584; CheW. PF02895; H-kinase_dim. PF02518; HATPase_c. PF01627; Hpt. PF00072; Response_reg. SMART: SM00260; CheW. SM00387; HATPase_c. SM00073; HPT. SM00448; REC. HTH reporting nucleic acid binding motif; Function unclear.
 
 0.998
pilJ
Probable pilus biogenesis protein,; High confidence in function and specificity.
 
 0.996
pilG
Pilus protein, Response_reg. Pfam: PF00072; Response_reg. SMART: SM00448; REC. PilG protein. IS INVOLVED IN PILUS BIOSYNTHESIS AND TWITCHING MOTILITY. MAY ACT AS A SINGLE-DOMAIN RESPONSE REGULATOR WHOSE FUNCTION MAY BE TO RECEIVE A CERTAIN ENVIRONMENTAL SIGNAL(S) AND THEN TRANSDUCE THAT SIGNAL TO THE PILUS ASSEMBLY MACHINERY VIA SPECIFIC PROTEIN-PROTEIN INTERACTIONS; High confidence in function and specificity.
 
 
 0.993
pilH
Pilus protein, Response_reg. Pfam: PF00072; Response_reg. SMART: SM00448; REC. PilH protein. MAY BE A PART OF A SIGNAL-TRANSDUCTION SYSTEM THAT REGULATES TWITCHING MOTILITY BY CONTROLLING PILUS FUNCTION (EXTENSION AND RETRACTION); High confidence in function and specificity.
 
 
 0.991
tcp
Putative citrate chemoreceptor protein; Salmonella typhimurium shows an attractant response to citrate and a repellent response to phenol, and a chemoreceptor mediating these responses has been identified and named Tcp (taxis to citrate and away from phenol). Similar to sprot|MCPC_SALTY (32%)and to trembl|Q82TM2. InterPro (IPR004089): Bacterial chemotaxis sensory transducer InterPro (IPR003660): HAMP InterPro (IPR004090): Methyl-accepting chemotaxis protein InterPro (IPR001610): PAC InterPro (IPR000014): PAS_domain Pfam (PF00672): HAMP Pfam (PF00015): MCPsignal Pfam (PF00785): PAC Pfam [...]
  
 0.947
cheA1
Putative chemotaxis histidine kinase protein,ATPbind_ATPase. IPR004358; Bact_sens_pr_C. IPR002545; CheW. IPR004105; H-kinase_dim. IPR005467; His_kinase. IPR008207; Hpt. IPR008208; Hpt_N. Pfam: PF01584; CheW. PF02895; H-kinase_dim. PF02518; HATPase_c. PF01627; Hpt. SMART: SM00260; CheW. SM00387; HATPase_c. SM00073; HPT. Chemotaxis protein cheA (EC 2.7.3.-). INVOLVED IN THE TRANSMISSION OF SENSORY SIGNALS FROM THE CHEMORECEPTORS TO THE FLAGELLAR MOTORS. CHEA IS AUTOPHOSPHORYLATED; IT CAN TRANSFER ITS PHOSPHATE GROUP TO EITHER CHEB OR CHEY; High confidence in function and specificity.
  
 0.935
cheA2
Chemotaxis protein cheA; INVOLVED IN THE TRANSMISSION OF SENSORY SIGNALS FROM THE CHEMORECEPTORS TO THE FLAGELLAR MOTORS. CHEA IS AUTOPHOSPHORYLATED; IT CAN TRANSFER ITS PHOSPHATE GROUP TO EITHER CHEB OR CHEY. EMBL AE005411; AAG56878.1; -. AP002559; BAB36021.1; -. PIR B85802; B85802. F90953; F90953. InterPro IPR003594; ATPbind_ATPase. IPR004358; Bact_sens_pr_C. IPR002545; CheW. IPR000629; DEAD_box. IPR004105; H-kinase_dim. IPR005467; His_kinase. IPR009082; His_kin_homodim. IPR008207; Hpt. IPR008208; Hpt_N. Pfam PF01584; CheW; 1. PF02895; H-kinase_dim; 1. PF02518; HATPase_c; 1. PF01627; [...]
  
 0.935
cheA3
Chemotaxis histidine kinase protein,ATPbind_ATPase. IPR004358; Bact_sens_pr_C. IPR002545; CheW. IPR004105; H-kinase_dim. IPR005467; His_kinase. IPR008207; Hpt. IPR008208; Hpt_N. Pfam: PF01584; CheW. PF02895; H-kinase_dim. PF02518; HATPase_c. PF01627; Hpt. SMART: SM00260; CheW. SM00387; HATPase_c. SM00073; HPT. Chemotaxis protein cheA (EC 2.7.3.-). INVOLVED IN THE TRANSMISSION OF SENSORY SIGNALS FROM THE CHEMORECEPTORS TO THE FLAGELLAR MOTORS. CHEA IS AUTOPHOSPHORYLATED; IT CAN TRANSFER ITS PHOSPHATE GROUP TO EITHER CHEB OR CHEY; High confidence in function and specificity.
  
 0.935
azo3381
Hypothetical signaling protein.
  
 0.929
azo1817
Conserved hypothetical two-component hybrid sensor and regulator. Homology to ebA6890 of Azoarcus sp. EbN1 of 56% (gnl|keqq|eba:ebA6890(KEGG)). InterPro: IPR003594 ATPbind_ATPase. IPR004358 Bact_sens_pr_C. IPR005467 His_kinase. IPR003661 His_kinA_N. IPR009082 His_kin_homodim. IPR001610 PAC. IPR000700 PAS-assoc_C. IPR000014 PAS_domain. IPR001789 Response_reg. Pfam: PF02518 HATPase_c. PF00512 HisKA. PF00785 PAC. PF00989 PAS. PF00072 Response_reg. SMART: SM00387 HATPase_c. SM00388 HisKA. SM00086 PAC. SM00091 PAS. SM00448 REC. TIGRFAM: TIGR00229 sensory_box; 3 TMHMM reporting 7 transmembra [...]
  
 0.899
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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