| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| algH | azo1411 | azo3459 | azo1411 | Transcriptional regulator,; Specificity unclear; Belongs to the UPF0301 (AlgH) family. | Conserved hypothetical ribonucleoside reductase; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. | 0.979 |
| algH | deaD | azo3459 | azo2122 | Transcriptional regulator,; Specificity unclear; Belongs to the UPF0301 (AlgH) family. | ATP-dependent RNA helicase; DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation. | 0.665 |
| algH | dnaN | azo3459 | azo0002 | Transcriptional regulator,; Specificity unclear; Belongs to the UPF0301 (AlgH) family. | DNA-directed DNA polymerase; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of repl [...] | 0.779 |
| algH | pyrB | azo3459 | azo3462 | Transcriptional regulator,; Specificity unclear; Belongs to the UPF0301 (AlgH) family. | Aspartate carbamoyltransferase (Aspartate transcarbamylase) (Carbamylaspartotranskinase) (ATCase); High confidence in function and specificity; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.875 |
| algH | pyrR | azo3459 | azo3461 | Transcriptional regulator,; Specificity unclear; Belongs to the UPF0301 (AlgH) family. | Phosphoribosyl transferase or bifunctional regulator/uracil phosphoribosyltransferase; High confidence in function and specificity. | 0.827 |
| algH | pyrX | azo3459 | azo3463 | Transcriptional regulator,; Specificity unclear; Belongs to the UPF0301 (AlgH) family. | Probable dihydroorotase. Homology to pyrC' of P. putida of 44% (sprot|PYRX_PSEPU) This protein tends to appear in a large, multifunctional complex with aspartate transcarbamoylase. It is inactive but is required as a non-catalytic subunit of aspartate transcarbamoylase. InterPro: Dihydroorotase multifunctional complex type (IPR004722); Dihydroorotase (IPR002195) Tigrfam: pyrC_multi: dihydroorotase multifunctional complex type no signal peptide no TMHS; High confidence in function and specificity. | 0.671 |
| algH | rhlE1 | azo3459 | azo0316 | Transcriptional regulator,; Specificity unclear; Belongs to the UPF0301 (AlgH) family. | ATP-dependent RNA helicase; Family membership; Belongs to the DEAD box helicase family. | 0.665 |
| algH | rhlE2 | azo3459 | azo1008 | Transcriptional regulator,; Specificity unclear; Belongs to the UPF0301 (AlgH) family. | Putative ATP-dependent RNA helicase rhlE; Family membership; Belongs to the DEAD box helicase family. | 0.704 |
| algH | rhlE3 | azo3459 | azo3522 | Transcriptional regulator,; Specificity unclear; Belongs to the UPF0301 (AlgH) family. | Putative ATP-dependent RNA helicase; DEAD-box RNA helicase involved in ribosome assembly. Has RNA- dependent ATPase activity and unwinds double-stranded RNA. | 0.708 |
| algH | yqgF | azo3459 | azo3460 | Transcriptional regulator,; Specificity unclear; Belongs to the UPF0301 (AlgH) family. | Putative Hollyday junction resolvase; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF nuclease family. | 0.960 |
| azo1411 | algH | azo1411 | azo3459 | Conserved hypothetical ribonucleoside reductase; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. | Transcriptional regulator,; Specificity unclear; Belongs to the UPF0301 (AlgH) family. | 0.979 |
| azo1411 | dnaN | azo1411 | azo0002 | Conserved hypothetical ribonucleoside reductase; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. | DNA-directed DNA polymerase; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of repl [...] | 0.856 |
| deaD | algH | azo2122 | azo3459 | ATP-dependent RNA helicase; DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation. | Transcriptional regulator,; Specificity unclear; Belongs to the UPF0301 (AlgH) family. | 0.665 |
| dnaN | algH | azo0002 | azo3459 | DNA-directed DNA polymerase; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of repl [...] | Transcriptional regulator,; Specificity unclear; Belongs to the UPF0301 (AlgH) family. | 0.779 |
| dnaN | azo1411 | azo0002 | azo1411 | DNA-directed DNA polymerase; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of repl [...] | Conserved hypothetical ribonucleoside reductase; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. | 0.856 |
| pyrB | algH | azo3462 | azo3459 | Aspartate carbamoyltransferase (Aspartate transcarbamylase) (Carbamylaspartotranskinase) (ATCase); High confidence in function and specificity; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | Transcriptional regulator,; Specificity unclear; Belongs to the UPF0301 (AlgH) family. | 0.875 |
| pyrB | pyrR | azo3462 | azo3461 | Aspartate carbamoyltransferase (Aspartate transcarbamylase) (Carbamylaspartotranskinase) (ATCase); High confidence in function and specificity; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | Phosphoribosyl transferase or bifunctional regulator/uracil phosphoribosyltransferase; High confidence in function and specificity. | 0.999 |
| pyrB | pyrX | azo3462 | azo3463 | Aspartate carbamoyltransferase (Aspartate transcarbamylase) (Carbamylaspartotranskinase) (ATCase); High confidence in function and specificity; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | Probable dihydroorotase. Homology to pyrC' of P. putida of 44% (sprot|PYRX_PSEPU) This protein tends to appear in a large, multifunctional complex with aspartate transcarbamoylase. It is inactive but is required as a non-catalytic subunit of aspartate transcarbamoylase. InterPro: Dihydroorotase multifunctional complex type (IPR004722); Dihydroorotase (IPR002195) Tigrfam: pyrC_multi: dihydroorotase multifunctional complex type no signal peptide no TMHS; High confidence in function and specificity. | 0.999 |
| pyrB | yqgF | azo3462 | azo3460 | Aspartate carbamoyltransferase (Aspartate transcarbamylase) (Carbamylaspartotranskinase) (ATCase); High confidence in function and specificity; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | Putative Hollyday junction resolvase; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF nuclease family. | 0.877 |
| pyrR | algH | azo3461 | azo3459 | Phosphoribosyl transferase or bifunctional regulator/uracil phosphoribosyltransferase; High confidence in function and specificity. | Transcriptional regulator,; Specificity unclear; Belongs to the UPF0301 (AlgH) family. | 0.827 |