STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
azo3467Conserved hypothetical protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. (237 aa)    
Predicted Functional Partners:
azo3465
Conserved hypothetical YGGT-family protein. Homology to ne0394 of N. europae of 37% (trembl|Q82X94). This family consists of a repeat found in conserved hypothetical integral membrane proteins. The function of this region and the proteins which possess it is unknown. InterPro: YGGT family (IPR003425). Pfam: YGGT family. no signal peptide. 5 TMHs; Conserved hypothetical protein.
 
  
 0.883
proC
Probable 1-pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
 
  
 0.813
azo3611
Maf-like protein; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
    0.802
azo1019
Conserved hypothetical protein. Homology to CV2191 of C.violaceum of 64% (tremble:Q7NVZ9). Has PF02578,Uncharacterised ACR, YfiH family COG1496. InterPro;IPR003730. No signal peptide. No TMHs. TIGR00726: conserved hypothetical protein; Belongs to the multicopper oxidase YfiH/RL5 family.
 
  
 0.791
yggU
Conserved hypothetical protein. Homology to vc0458 of V. clholerae of 48% (sprot:Y458_VIBCH). InterPro: DUF167 (IPR003748). Pfam: Uncharacterized ACR, YGGU family, COF1872. no signal peptide. no TMHs; Belongs to the UPF0235 family.
  
  
 0.713
rpmC
50S ribosomal protein L29; Family membership; Belongs to the universal ribosomal protein uL29 family.
  
    0.690
murF
UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate-D-alanyl-D-alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily.
  
    0.617
pilT
Twitching motility protein; Tfp retraction protein PilT, involved in the twitching motility mechanism together with PilU,; High confidence in function and specificity.
       0.611
rplX
50S ribosomal protein L24; One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
   
    0.605
rlmN
Conserved hypothetical protein; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity; Belongs to the radical SAM superfamily. RlmN family.
 
     0.602
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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