STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
vgrGProbable vgr-related protein, 44% identity(54% similarity) to TrEMBL; Q7P238.TrEMBL;Q8XRU3(44% identity). Signal Peptide Present. Has SMART;SM00438,Repressor of transcription;IPR000967, Znf_NFX1;This domain is presumed to be a zinc binding domain. The following pattern describes the zinc finger: C-X(1-6)-H-X-C-X3-C(H/C)-X(3-4)-(H/C)-X(1-10)-C,where X can be any amino acid, and numbers in brackets indicate the number of residues. The two position can be either his or cys. This domain is found in the human transcriptional repressor NK-X1, a repressor of HLA-DRA transcription; the Drosoph [...] (905 aa)    
Predicted Functional Partners:
sciA
Putative cytoplasmic protein,sciA. TrEMBL;Q83SK5, Q7AXZ5 Has PF06812, ImpA-related N-terminal;IPR010657,ImpA_N;This family represents a conserved region located towards the N-terminal end of ImpA and related proteins. ImpA is an inner membrane protein, which has been suggested to be involved with proteins that are exported and associated with colony variations in Actinobacillus actinomycetemcomitans. Note that many family members are hypothetical proteins; Conserved hypothetical protein.
 
  
 0.925
azo1309
Conserved hypothetical protein. Homology to CV3967 of C.violaceum of 45% (tremble:Q7NR18) Has (IPR010732)PF06996:Protein of unknown function (DUF1305);This family consists of several hypothetical bacterial proteins of around 300 residues in length. The function of this family is unknown although one member (Q93IT4) from Salmonella enterica is thought to be involved in virulence. No signal peptide or TMH reported present.
 
 
 0.909
sciB
Putative cytoplasmic protein, sciB. TrEMBl;Q93IT4(36% identity) Has PF06996;Protein of unknown function (DUF1305);IPR010732; This family consists of several hypothetical bacterial proteins of around 300 residues in length. The function of this family is unknown although one member (Q93IT4) from Salmonella enterica is thought to be involved in virulence; Conserved hypothetical protein.
 
 
 0.908
azo1303
Hypothetical protein,50% identity (66% Similarity) to TrEMBL;Q8XRT8. TrEMBL;Q7NR06(60% identity,74% similarity). Has PF05591;Protein of unknown function (DUF770)(IPR008312)This family consists of several proteins of unknown function from various bacterial species. No Signal peptide or TMH present; Function unclear.
 
  
 0.896
sciH
Putative cytoplasmic protein,sciH, 71% identity(87% similarity) to TrEMBL;Q7AXZ1. Has PF05591, Protein of unknown function (DUF770);IPR008312,UCP028301;This family consists of several proteins of unknown function from various bacterial species. These proteins are encoded in pathogenic and symbiotic bacteria as part of an operon (part of the SCI genomic island in Salmonella enterica and the imp locus in Rhizobium leguminosarum) implicated in pathogenicity and protein secretion.These proteins are SciH/ImpB; High confidence in function and specificity.
 
  
 0.894
azo1305
Conserved hypothetical protein. Homology to CV3977 of C.violaceum of 77% (tremble:Q7NR08). Has PF05638:(IPR008514)Protein of unknown function (DUF796);This family consists of several bacterial proteins of unknown function. No signal peptide or TMH present.
 
  
 0.888
sciK
Putative cytoplasmic protein,sciK, 33% identity to TrEMBL;Q7AXZ0. Has PF05638, Protein of unknown function (DUF796);This family consists of several bacterial proteins of unknown function. Signal Peptide or TMH absent; Conserved hypothetical protein.
 
  
 0.882
sciM
Putative cytoplasmic protein,sciM, 33% identity(50% similarity) to TrEMBL;Q7AXY8. Has PF05638,Protein of unknown function (DUF796);IPR008514;This family consists of several bacterial proteins of unknown function; High confidence in function and specificity.
 
  
 0.880
ompA2
Putative outer membrane protein, OmpA family,36% identity(51%similarity) to TrEMBL;Q93IS0.TrEMBL;Q7AXY6(36% identity) TMHMM2 reporting presence of 1 TMH's. Has PF00691, OmpA family;IPR006665, OmpA/MotB:Most of the bacterial outer membrane proteins in this group are porin-like integral membrane proteins (such as ompA) MEDLINE:,but some are small lipid-anchored proteins.It is also found in MotB and related proteins. They are present in the outer membrane of many Gram-negative organisms; Conserved hypothetical protein.
 
  
 0.856
azo1297
Conserved hypothetical protein. Homology to CV3985 of C.violaceum of 42% (tremble:Q7NR00). Has PF07025:(IPR010745)Protein of unknown function (DUF1316);This family consists of several hypothetical bacterial proteins of around 150 residues in length. The function of this family is unknown. No signal peptide or TMH present.
 
  
 0.853
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.