Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
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Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
mobAProbable molybdopterin-guanine dinucleotide biosynthesis protein A; Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor; Belongs to the MobA family. (213 aa)    
Predicted Functional Partners:
mobB2
Molybdopterin-guanine dinucleotide biosynthesis protein B. MAY BIND THE GUANINE NUCLEOTIDE REQUIRED FOR THE SYNTHESIS OF MOLYBDOPTERIN GUANINE DINUCLEOTIDE. InterPro: ATP/GTP-binding site motif A (P-loop) TIGRFAM: mobB: molybdopterin-guanine dinucleotide; High confidence in function and specificity.
 0.988
mobB1
Molybdopterin-guanine dinucleotide biosynthesis protein B. may bind the guanine nucleotide required for the synthesis of molybdopterin guanine dinucleotide. mobB: molybdopterin-guanine dinucleotide; High confidence in function and specificity.
 0.982
fdhD
Putative formate dehydrogenase accessory protein; Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH. Belongs to the FdhD family.
 
 
 0.968
moeA2
Molybdopterin biosynthesis protein; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family.
 0.941
moeA1
Molybdopterin cofactor biosynthesis protein; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family.
 0.915
azo3490
Conserved hypothetical protein. Homology to ebA2947 of Azoarcus sp. EbN1 of 58% (gnl|keqq|eba:ebA2947(KEGG)). No domains predicted. No signal peptide. No TMHs.
 
 
 0.910
moaC
Molybdenum cofactor biosynthesis protein C; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family.
  
 0.887
azo0024
Conserved hypothetical protein; Purine catabolism protein pucB. TREMBL:Q8XZ0: 40% identity, 47% similarity Required for xanthine dehydrogenase activity. Could be involved in formation of the molybdenum cofactor required by xanthine dehydrogenase. FUNCTION: Links a guanosine 5'-phosphate to molydopterin (MPT) forming molybdopterin guanine dinucleotide (MGD) (By similarity). PATHWAY: Molybdenum cofactor biosynthesis. SUBCELLULAR LOCATION: Cytoplasmic (By similarity). SIMILARITY: Belongs to the mobA family. Pfam:UPF0007:Uncharacterized protein family UPF000 ispD: 4-diphosphocytidyl-2C-met [...]
    
 0.873
moaA
Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate.
 
 
 0.829
moaE
Molybdenum cofactor biosynthesis protein E; Molybdopterin converting factor subunit 2 (MPT synthase subunit 2) (Molybdopterin synthase subunit 2). Converts molybdopterin precursor Z into molybdopterin. This requires the incorporation of two sulfur atoms into precursor Z to generate a dithiolene group; High confidence in function and specificity.
 
 
 0.805
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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