STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
azo3490Conserved hypothetical protein. Homology to ebA2947 of Azoarcus sp. EbN1 of 58% (gnl|keqq|eba:ebA2947(KEGG)). No domains predicted. No signal peptide. No TMHs. (306 aa)    
Predicted Functional Partners:
fdhD
Putative formate dehydrogenase accessory protein; Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH. Belongs to the FdhD family.
 
  
  0.963
mobA
Probable molybdopterin-guanine dinucleotide biosynthesis protein A; Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor; Belongs to the MobA family.
 
 
 0.901
azo3487
Conserved hypothetical protein. Homology to BPP1929 of B.parapertussis of 34% (trembl:34%). No signal peptide or TMH reported present. No domains predicted.
 
 
 0.877
azo3486
Conserved hypothetical protein. Homology to RS01168 of R.solanacearum of 40% (trembl:Q8XWU3). No domains predicted. No signal peptide or TMH reported present.
 
     0.851
tupB
Probable tungstate permease protein. Homology to tupB of E. acidaminophilum of 40% (tremble: Q93KD5) Permase of an abc-transport system involved in transport of oxyanions. no signal peptide probable 5 TMHs; Family membership.
 
    0.786
azo3832
Putative ABC-type tungstate transport system,permease component; Function unclear.
 
     0.771
azo3843
Putative exported protein.SignalP reporting signal peptice. Most likely cleavage site between pos. 27 and 28: AHA-AP; Function unclear.
 
     0.769
azo3833
31% HTH_9; 1. InterPro: IPR003725; ModE:Molybdenum-binding protein N-terminal. ModE are involved in molybdenum transport.These proteins acts both as a repressor and activator of the mod and moa operons,respectively, depending on the properties of the binding site; High confidence in function and specificity.
 
     0.764
fdhA2
Probable formate dehydrogenase alpha subunit. Homology to fdha of W. succinogenes of 44% (pir|S18213) The formate dehydrogenase catalyzes the oxidation of formate (produced from pyruvate during anaerobic growth) to carbon dioxide with the concomitant release of two electrons and two protons. The electrons are utilized mainly in the nitrate respiration by nitrate reductase InterPro: Prokaryotic molybdopterin oxidoreductases (IPR006655) Pfam: Molybdopterin oxidoreductase; Molydopterin dinucleotide binding domain singal peptide no TMHs; High confidence in function and specificity.
 
     0.734
torD
Putative Chaperone protein TorD. Homology to torD of E. coli of 23% (sprot|TORD_ECOLI). This family consists of several bacterial TorD proteins. Many prokaryotic molybdoenzymes, for example the TMAO reductase (TorA) of Escherichia coli, require the insertion of a bis(molybdopterin guanine dinucleotide) molybdenum (bis(MGD)Mo) cofactor in its catalytic site to be active and translocated to the periplasm. The TorD chaperone increases apoTorA activation up to four-fold, allowing maturation of most of the apoprotein. Therefore TorD is involved in the first step of TorA maturation to make i [...]
 
     0.727
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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