STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
ureGUrease accessory protein UreG; Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG. (207 aa)    
Predicted Functional Partners:
ureF
Probable urease accessory protein UreF; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
 
 
 0.996
ureE
Probable urease accessory protein UreE; Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly. Belongs to the UreE family.
 
 
 0.978
ureD
Putative urease accessory protein UreD; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
 
 
 0.971
ureC
Urease alpha subunit. Homology to ureC of S. meliloti of 75% (sprot|URE1_RHIME). Urease (urea amidohydrolase, EC: 3.5.1.5) catalyses the hydrolysis of urea to form ammonia and carbamate. The enzyme consists of three structural domains: an alpha subunit (with the C-terminal two-thirds representing the catalytic domain), a beta subunit and a gamma subunit. Pfam: Urease alpha-subunit, catalytic domain; Urease alpha-subunit N-terminal domain no signal peptide no TMHs; High confidence in function and specificity.
 
  
 0.960
ureB
Probable urease beta subunit; Region start changed from 3848352 to 3848310 (-42 bases); Belongs to the urease beta subunit family.
 
  
 0.957
ureA
Urease gamma subunit. Homology to ureA of S. meliloti of 71% (sprot|URE3_RHIME) Urease (urea amidohydrolase, EC: 3.5.1.5) catalyses the hydrolysis of urea to form ammonia and carbamate. The enzyme consists of three structural domains: an alpha subunit (with the C-terminal two-thirds representing the catalytic domain), a beta subunit and a gamma subunit. InterPro: Urease gamma subunit (IPR002026) Pfam: urease, gamma subunit Tigrfam: urease_gam: urease gamma subunit no signal peptide no TMHs; High confidence in function and specificity.
 
  
 0.954
hypA
Probable hydrogenase nickel inorporation protein hypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
  
 
 0.813
azo2062
Conserved hypothetical peptidyl-prolyl cis-trans isomerase. Homology to slyD of E. coli of 41% (sprot|SLYD_ECOLI) but around 30 aa at the C-terminus are missing. Peptidylprolyl isomerases accelerate protein folding by catalyzing the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. InterPro: FKBP-type peptidyl-prolyl cis-trans isomerase (PPIase) (IPR001179). Pfam: FKBP-type peptidyl-prolyl cis-trans isomerase. no signal peptide. no TMHs; Family membership.
    
 
 0.798
hypD
Hydrogenase expression/formation protein hypD. Homology to hypD of A. eutrophus of 71% (sprot|HYPD_ALCEU). HypD is involved in hydrogenase formation. InterPro: Hydrogenase formation hypA (IPR002780) Pfam: Hydrogenase formation hypA family Tigrfam: hypD: hydrogenase expression/formation no signal peptide no TMHs; High confidence in function and specificity; Belongs to the HypD family.
  
  
 0.729
hypC
Probable hydrogenase assembly chaperon HypC. Homology to hypC of R. leguminosarum of 61% (sprot|HYPC_RHILV). Forms a family of small proteins that are hydrogenase precursor-specific chaperones required for this maturation process. They are believed to keep the hydrogenase precursor in a conformation accessible for metal incorporation. Pfam: HypF/HypC family Tigrfam: hypC_hupF: hydrogenase assembly chaperone no signal peptide no TMHs; Function unclear.
  
  
 0.728
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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