Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
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[Homology]
Score
ureEProbable urease accessory protein UreE; Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly. Belongs to the UreE family. (159 aa)    
Predicted Functional Partners:
ureF
Probable urease accessory protein UreF; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
  
 0.985
ureD
Putative urease accessory protein UreD; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
 
   
 0.913
ureC
Urease alpha subunit. Homology to ureC of S. meliloti of 75% (sprot|URE1_RHIME). Urease (urea amidohydrolase, EC: 3.5.1.5) catalyses the hydrolysis of urea to form ammonia and carbamate. The enzyme consists of three structural domains: an alpha subunit (with the C-terminal two-thirds representing the catalytic domain), a beta subunit and a gamma subunit. Pfam: Urease alpha-subunit, catalytic domain; Urease alpha-subunit N-terminal domain no signal peptide no TMHs; High confidence in function and specificity.
 
  
 0.903
ureG
Urease accessory protein UreG; Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
 
 
 0.894
ureB
Probable urease beta subunit; Region start changed from 3848352 to 3848310 (-42 bases); Belongs to the urease beta subunit family.
 
   
 0.887
ureA
Urease gamma subunit. Homology to ureA of S. meliloti of 71% (sprot|URE3_RHIME) Urease (urea amidohydrolase, EC: 3.5.1.5) catalyses the hydrolysis of urea to form ammonia and carbamate. The enzyme consists of three structural domains: an alpha subunit (with the C-terminal two-thirds representing the catalytic domain), a beta subunit and a gamma subunit. InterPro: Urease gamma subunit (IPR002026) Pfam: urease, gamma subunit Tigrfam: urease_gam: urease gamma subunit no signal peptide no TMHs; High confidence in function and specificity.
 
  
 0.870
hypB
Probable hydrogenase accessory protein HypB. Homology to hypB of E. coli of 56% (sprot|HYPB_ECOLI). IS REQUIRED FOR THE FORMATION OF HYDROGENASE ISOENZYMES. AFFECTS SOME ASPECT OF THE PROCESSING OF HYDROGENASES and NICKEL INCORPORATION scince HYPB GENE LESIONS CAN BE COMPLEMENTED BY HIGH NICKEL ION CONCENTRATION IN THE MEDIUM. Pfam: HypB/UreG nucleotide-binding domain Tigrfam: hypB: hydrogenase accessory protein Hyp no signal peptide no TMHs; High confidence in function and specificity.
  
 
 0.640
urtD
Conserved hypothetical ABC transporter, ATP binding protein. Homology to pp4844 of P. putida of 70% (trembl|Q88DI1). Probable component of a branched-chain amino-acid transport system. Pfam: ABC-Transporter no signal peptide no TMHs; Family membership.
 
   
 0.637
urtC
Probable ABC transporter, membrane spanning protein. Homology to urtC of Anabaena sp. of 41% (involved in urea transport). Part of the binding-protein-dependent transport system. Probably responsible for the translocation of the substrates across the membrane. InterPro: Binding-system dependent bacterial transporters (araH livH/limM families) Pfam: Branched-chain amino acid transport system signal peptide probable 9 TMHs; Function unclear.
 
   
 0.580
amiC2
Putative aliphatic amidase expression-regulating protein; AmiC regulates the expression of the inducible aliphatic amidase activity in Pseudomonas aeruginosa. Similar to trembl|Q87VQ0 (80%) and to sprot|AMIC_PSEAE (27%). Pfam (PF01094): Receptor family ligand binding region SignalP reporting Signal peptide; Specificity unclear.
 
   
 0.570
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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