Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
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[Homology]
Score
ureAUrease gamma subunit. Homology to ureA of S. meliloti of 71% (sprot|URE3_RHIME) Urease (urea amidohydrolase, EC: 3.5.1.5) catalyses the hydrolysis of urea to form ammonia and carbamate. The enzyme consists of three structural domains: an alpha subunit (with the C-terminal two-thirds representing the catalytic domain), a beta subunit and a gamma subunit. InterPro: Urease gamma subunit (IPR002026) Pfam: urease, gamma subunit Tigrfam: urease_gam: urease gamma subunit no signal peptide no TMHs; High confidence in function and specificity. (100 aa)    
Predicted Functional Partners:
ureC
Urease alpha subunit. Homology to ureC of S. meliloti of 75% (sprot|URE1_RHIME). Urease (urea amidohydrolase, EC: 3.5.1.5) catalyses the hydrolysis of urea to form ammonia and carbamate. The enzyme consists of three structural domains: an alpha subunit (with the C-terminal two-thirds representing the catalytic domain), a beta subunit and a gamma subunit. Pfam: Urease alpha-subunit, catalytic domain; Urease alpha-subunit N-terminal domain no signal peptide no TMHs; High confidence in function and specificity.
 0.999
ureB
Probable urease beta subunit; Region start changed from 3848352 to 3848310 (-42 bases); Belongs to the urease beta subunit family.
 0.999
ureD
Putative urease accessory protein UreD; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
 
 
 0.993
ureF
Probable urease accessory protein UreF; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
 
 
 0.981
ureE
Probable urease accessory protein UreE; Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly. Belongs to the UreE family.
 
  
 0.870
ureG
Urease accessory protein UreG; Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
 
   
 0.869
alc
Allantoicase (Allantoate amidinohydrolase); High confidence in function and specificity; Belongs to the allantoicase family.
    
  0.781
azo3506
Conserved hypothetical protein. Homology to Daro03003730 of Dechloromonas aromatica of 40% (gi|46140350|ref|ZP_00203571.1|(NBCI ENTREZ)). no domains predicted. no signal peptide. no TMHs; Family membership.
       0.664
azo3692
Putative N-acetyltransferase,51% Identity to TrEMBl;Q7WQB1,54% Identity to TrEMBL;Q63LT2,Q7WCA7. Has PF00583, Acetyltransferase (GNAT) family;IPR000182,GCN5acetyl_trans; This family contains proteins with N-acetyltransferase functions. Histone acetylation is carried out by a class of enzymes known as histone acetyltransferases (HATs), which catalyze the transfer of an acetyl group from acetyl-CoA to the lysine E -amino groups on the N-terminal tails of histones. Early indication that HATs were involved in transcription came from the observation that in actively transcribed regions of c [...]
  
    0.626
azo0044
Conserved hypothetical urea amidolyase-related protein. Homology to ybgK of E. coli of 36% (sprot|YBGK_ECOLI). InterPro: DUF183 (IPR003778) Uncharacterized domain in proteins of unknown function. This domain is found in a multifunctional enzyme, urea amidolyase, from yeast. Pfam: DFU182, uncharcterized ACR,COG1984 no signal peptide no TMHs; Function unclear.
     
 0.548
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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