node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
azo3529 | cbiC | azo3529 | azo3531 | Probable Precorrin-4 C11-methyltransferase,47% Identity to TrEMBL;Q8GDX1, O26702. SwissProt;O87696. Has PF00590, Tetrapyrrole (Corrin/Porphyrin) Methylases;IPR000878 Cor/por_Metransf; This family uses S-AdoMet in the methylation of diverse substrates. This family includes a related group of bacterial proteins of unknown function, including P45528. This family includes the methylase Dipthine synthase. Uroporphyrin-III C-methyltransferase (EC: 2.1.1.107) (SUMT)catalyzes the transfer of two methyl groups from S-adenosyl-L-methionine to the C-2 and C-7 atoms of uroporphyrinogen III to yiel [...] | Precorrin-8X methylmutase. CATALYZES THE CONVERSION OF PRECORRIN-8X TO HYDROGENOBYRINIC ACID; A Cobalamin biosynthesis precorrin isomerase. METHYL MIGRATION REACTION DURING THE TRANSFORMATION OF PRECORRIN-3 TO FORM COBYRINIC ACID (BY SIMILARITY). InterPro: Precorrin-8X methylmutase CbiC/CobH TIGRFAM: redox_disulf_1: redox-active disulfide; High confidence in function and specificity. | 0.998 |
azo3529 | cbiH | azo3529 | azo3537 | Probable Precorrin-4 C11-methyltransferase,47% Identity to TrEMBL;Q8GDX1, O26702. SwissProt;O87696. Has PF00590, Tetrapyrrole (Corrin/Porphyrin) Methylases;IPR000878 Cor/por_Metransf; This family uses S-AdoMet in the methylation of diverse substrates. This family includes a related group of bacterial proteins of unknown function, including P45528. This family includes the methylase Dipthine synthase. Uroporphyrin-III C-methyltransferase (EC: 2.1.1.107) (SUMT)catalyzes the transfer of two methyl groups from S-adenosyl-L-methionine to the C-2 and C-7 atoms of uroporphyrinogen III to yiel [...] | Precorrin-3B C17- methyltransferase. METHYLTRANSFERASE THAT CATALYZES THE METHYLATION OF C-17 IN PRECORRIN-3B TO FORM PRECORRIN-4 (BY SIMILARITY). InterPro: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; High confidence in function and specificity. | 0.999 |
azo3529 | cbiL | azo3529 | azo3534 | Probable Precorrin-4 C11-methyltransferase,47% Identity to TrEMBL;Q8GDX1, O26702. SwissProt;O87696. Has PF00590, Tetrapyrrole (Corrin/Porphyrin) Methylases;IPR000878 Cor/por_Metransf; This family uses S-AdoMet in the methylation of diverse substrates. This family includes a related group of bacterial proteins of unknown function, including P45528. This family includes the methylase Dipthine synthase. Uroporphyrin-III C-methyltransferase (EC: 2.1.1.107) (SUMT)catalyzes the transfer of two methyl groups from S-adenosyl-L-methionine to the C-2 and C-7 atoms of uroporphyrinogen III to yiel [...] | Precorrin-2 C20-methyltransferase (EC 2.1.1.130) (S-adenosyl-L- methionine:precorrin-2 methyltransferase) (SP2MT). METHYLATES PRECORRIN-2 AT THE C-20 POSITION TO PRODUCE PRECORRIN-3A; High confidence in function and specificity. | 0.998 |
azo3529 | cobB | azo3529 | azo3550 | Probable Precorrin-4 C11-methyltransferase,47% Identity to TrEMBL;Q8GDX1, O26702. SwissProt;O87696. Has PF00590, Tetrapyrrole (Corrin/Porphyrin) Methylases;IPR000878 Cor/por_Metransf; This family uses S-AdoMet in the methylation of diverse substrates. This family includes a related group of bacterial proteins of unknown function, including P45528. This family includes the methylase Dipthine synthase. Uroporphyrin-III C-methyltransferase (EC: 2.1.1.107) (SUMT)catalyzes the transfer of two methyl groups from S-adenosyl-L-methionine to the C-2 and C-7 atoms of uroporphyrinogen III to yiel [...] | Cobyrinic acid AC-diamide synthase. Responsible for the amidation of carboxylic groups at position A and C of either cobyrinic acid or hydrogenobrynic acid. NH(2) groups are provided by glutamine and one molecule of ATP is hydrogenolyzed for each amidation (By similarity). cbiA: cobyrinic acid ac-diamide synthase; High confidence in function and specificity. | 0.984 |
azo3529 | cobC | azo3529 | azo3519 | Probable Precorrin-4 C11-methyltransferase,47% Identity to TrEMBL;Q8GDX1, O26702. SwissProt;O87696. Has PF00590, Tetrapyrrole (Corrin/Porphyrin) Methylases;IPR000878 Cor/por_Metransf; This family uses S-AdoMet in the methylation of diverse substrates. This family includes a related group of bacterial proteins of unknown function, including P45528. This family includes the methylase Dipthine synthase. Uroporphyrin-III C-methyltransferase (EC: 2.1.1.107) (SUMT)catalyzes the transfer of two methyl groups from S-adenosyl-L-methionine to the C-2 and C-7 atoms of uroporphyrinogen III to yiel [...] | Cobalamin biosynthesis protein, CobC. CobC is probable involved in the conversion of cobyric acid to cobinamide.Similar to pir|B83486 (48%) and to sprot|COBC_PSEDE (42%). InterPro (PF00155): Aminotransferases class-I and II; Specificity unclear. | 0.694 |
azo3529 | cobD1 | azo3529 | azo2173 | Probable Precorrin-4 C11-methyltransferase,47% Identity to TrEMBL;Q8GDX1, O26702. SwissProt;O87696. Has PF00590, Tetrapyrrole (Corrin/Porphyrin) Methylases;IPR000878 Cor/por_Metransf; This family uses S-AdoMet in the methylation of diverse substrates. This family includes a related group of bacterial proteins of unknown function, including P45528. This family includes the methylase Dipthine synthase. Uroporphyrin-III C-methyltransferase (EC: 2.1.1.107) (SUMT)catalyzes the transfer of two methyl groups from S-adenosyl-L-methionine to the C-2 and C-7 atoms of uroporphyrinogen III to yiel [...] | Cobalamin biosynthesis transmembrane protein; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. | 0.892 |
azo3529 | cobD2 | azo3529 | azo3518 | Probable Precorrin-4 C11-methyltransferase,47% Identity to TrEMBL;Q8GDX1, O26702. SwissProt;O87696. Has PF00590, Tetrapyrrole (Corrin/Porphyrin) Methylases;IPR000878 Cor/por_Metransf; This family uses S-AdoMet in the methylation of diverse substrates. This family includes a related group of bacterial proteins of unknown function, including P45528. This family includes the methylase Dipthine synthase. Uroporphyrin-III C-methyltransferase (EC: 2.1.1.107) (SUMT)catalyzes the transfer of two methyl groups from S-adenosyl-L-methionine to the C-2 and C-7 atoms of uroporphyrinogen III to yiel [...] | Putative cobalamin biosynthesis protein; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. | 0.941 |
azo3529 | cobO | azo3529 | azo3552 | Probable Precorrin-4 C11-methyltransferase,47% Identity to TrEMBL;Q8GDX1, O26702. SwissProt;O87696. Has PF00590, Tetrapyrrole (Corrin/Porphyrin) Methylases;IPR000878 Cor/por_Metransf; This family uses S-AdoMet in the methylation of diverse substrates. This family includes a related group of bacterial proteins of unknown function, including P45528. This family includes the methylase Dipthine synthase. Uroporphyrin-III C-methyltransferase (EC: 2.1.1.107) (SUMT)catalyzes the transfer of two methyl groups from S-adenosyl-L-methionine to the C-2 and C-7 atoms of uroporphyrinogen III to yiel [...] | Cob(I)yrinic acid a,c-diamide adenosyltransferase; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids. | 0.857 |
azo3529 | cobQ | azo3529 | azo3517 | Probable Precorrin-4 C11-methyltransferase,47% Identity to TrEMBL;Q8GDX1, O26702. SwissProt;O87696. Has PF00590, Tetrapyrrole (Corrin/Porphyrin) Methylases;IPR000878 Cor/por_Metransf; This family uses S-AdoMet in the methylation of diverse substrates. This family includes a related group of bacterial proteins of unknown function, including P45528. This family includes the methylase Dipthine synthase. Uroporphyrin-III C-methyltransferase (EC: 2.1.1.107) (SUMT)catalyzes the transfer of two methyl groups from S-adenosyl-L-methionine to the C-2 and C-7 atoms of uroporphyrinogen III to yiel [...] | Cobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. | 0.986 |
azo3529 | cobU | azo3529 | azo3557 | Probable Precorrin-4 C11-methyltransferase,47% Identity to TrEMBL;Q8GDX1, O26702. SwissProt;O87696. Has PF00590, Tetrapyrrole (Corrin/Porphyrin) Methylases;IPR000878 Cor/por_Metransf; This family uses S-AdoMet in the methylation of diverse substrates. This family includes a related group of bacterial proteins of unknown function, including P45528. This family includes the methylase Dipthine synthase. Uroporphyrin-III C-methyltransferase (EC: 2.1.1.107) (SUMT)catalyzes the transfer of two methyl groups from S-adenosyl-L-methionine to the C-2 and C-7 atoms of uroporphyrinogen III to yiel [...] | Cobinamide kinase/cobinamide phosphate guanylyltransferase; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate. | 0.843 |
cbiC | azo3529 | azo3531 | azo3529 | Precorrin-8X methylmutase. CATALYZES THE CONVERSION OF PRECORRIN-8X TO HYDROGENOBYRINIC ACID; A Cobalamin biosynthesis precorrin isomerase. METHYL MIGRATION REACTION DURING THE TRANSFORMATION OF PRECORRIN-3 TO FORM COBYRINIC ACID (BY SIMILARITY). InterPro: Precorrin-8X methylmutase CbiC/CobH TIGRFAM: redox_disulf_1: redox-active disulfide; High confidence in function and specificity. | Probable Precorrin-4 C11-methyltransferase,47% Identity to TrEMBL;Q8GDX1, O26702. SwissProt;O87696. Has PF00590, Tetrapyrrole (Corrin/Porphyrin) Methylases;IPR000878 Cor/por_Metransf; This family uses S-AdoMet in the methylation of diverse substrates. This family includes a related group of bacterial proteins of unknown function, including P45528. This family includes the methylase Dipthine synthase. Uroporphyrin-III C-methyltransferase (EC: 2.1.1.107) (SUMT)catalyzes the transfer of two methyl groups from S-adenosyl-L-methionine to the C-2 and C-7 atoms of uroporphyrinogen III to yiel [...] | 0.998 |
cbiC | cbiH | azo3531 | azo3537 | Precorrin-8X methylmutase. CATALYZES THE CONVERSION OF PRECORRIN-8X TO HYDROGENOBYRINIC ACID; A Cobalamin biosynthesis precorrin isomerase. METHYL MIGRATION REACTION DURING THE TRANSFORMATION OF PRECORRIN-3 TO FORM COBYRINIC ACID (BY SIMILARITY). InterPro: Precorrin-8X methylmutase CbiC/CobH TIGRFAM: redox_disulf_1: redox-active disulfide; High confidence in function and specificity. | Precorrin-3B C17- methyltransferase. METHYLTRANSFERASE THAT CATALYZES THE METHYLATION OF C-17 IN PRECORRIN-3B TO FORM PRECORRIN-4 (BY SIMILARITY). InterPro: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; High confidence in function and specificity. | 0.997 |
cbiC | cbiL | azo3531 | azo3534 | Precorrin-8X methylmutase. CATALYZES THE CONVERSION OF PRECORRIN-8X TO HYDROGENOBYRINIC ACID; A Cobalamin biosynthesis precorrin isomerase. METHYL MIGRATION REACTION DURING THE TRANSFORMATION OF PRECORRIN-3 TO FORM COBYRINIC ACID (BY SIMILARITY). InterPro: Precorrin-8X methylmutase CbiC/CobH TIGRFAM: redox_disulf_1: redox-active disulfide; High confidence in function and specificity. | Precorrin-2 C20-methyltransferase (EC 2.1.1.130) (S-adenosyl-L- methionine:precorrin-2 methyltransferase) (SP2MT). METHYLATES PRECORRIN-2 AT THE C-20 POSITION TO PRODUCE PRECORRIN-3A; High confidence in function and specificity. | 0.997 |
cbiC | cobB | azo3531 | azo3550 | Precorrin-8X methylmutase. CATALYZES THE CONVERSION OF PRECORRIN-8X TO HYDROGENOBYRINIC ACID; A Cobalamin biosynthesis precorrin isomerase. METHYL MIGRATION REACTION DURING THE TRANSFORMATION OF PRECORRIN-3 TO FORM COBYRINIC ACID (BY SIMILARITY). InterPro: Precorrin-8X methylmutase CbiC/CobH TIGRFAM: redox_disulf_1: redox-active disulfide; High confidence in function and specificity. | Cobyrinic acid AC-diamide synthase. Responsible for the amidation of carboxylic groups at position A and C of either cobyrinic acid or hydrogenobrynic acid. NH(2) groups are provided by glutamine and one molecule of ATP is hydrogenolyzed for each amidation (By similarity). cbiA: cobyrinic acid ac-diamide synthase; High confidence in function and specificity. | 0.996 |
cbiC | cobC | azo3531 | azo3519 | Precorrin-8X methylmutase. CATALYZES THE CONVERSION OF PRECORRIN-8X TO HYDROGENOBYRINIC ACID; A Cobalamin biosynthesis precorrin isomerase. METHYL MIGRATION REACTION DURING THE TRANSFORMATION OF PRECORRIN-3 TO FORM COBYRINIC ACID (BY SIMILARITY). InterPro: Precorrin-8X methylmutase CbiC/CobH TIGRFAM: redox_disulf_1: redox-active disulfide; High confidence in function and specificity. | Cobalamin biosynthesis protein, CobC. CobC is probable involved in the conversion of cobyric acid to cobinamide.Similar to pir|B83486 (48%) and to sprot|COBC_PSEDE (42%). InterPro (PF00155): Aminotransferases class-I and II; Specificity unclear. | 0.604 |
cbiC | cobD1 | azo3531 | azo2173 | Precorrin-8X methylmutase. CATALYZES THE CONVERSION OF PRECORRIN-8X TO HYDROGENOBYRINIC ACID; A Cobalamin biosynthesis precorrin isomerase. METHYL MIGRATION REACTION DURING THE TRANSFORMATION OF PRECORRIN-3 TO FORM COBYRINIC ACID (BY SIMILARITY). InterPro: Precorrin-8X methylmutase CbiC/CobH TIGRFAM: redox_disulf_1: redox-active disulfide; High confidence in function and specificity. | Cobalamin biosynthesis transmembrane protein; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. | 0.692 |
cbiC | cobD2 | azo3531 | azo3518 | Precorrin-8X methylmutase. CATALYZES THE CONVERSION OF PRECORRIN-8X TO HYDROGENOBYRINIC ACID; A Cobalamin biosynthesis precorrin isomerase. METHYL MIGRATION REACTION DURING THE TRANSFORMATION OF PRECORRIN-3 TO FORM COBYRINIC ACID (BY SIMILARITY). InterPro: Precorrin-8X methylmutase CbiC/CobH TIGRFAM: redox_disulf_1: redox-active disulfide; High confidence in function and specificity. | Putative cobalamin biosynthesis protein; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. | 0.856 |
cbiC | cobO | azo3531 | azo3552 | Precorrin-8X methylmutase. CATALYZES THE CONVERSION OF PRECORRIN-8X TO HYDROGENOBYRINIC ACID; A Cobalamin biosynthesis precorrin isomerase. METHYL MIGRATION REACTION DURING THE TRANSFORMATION OF PRECORRIN-3 TO FORM COBYRINIC ACID (BY SIMILARITY). InterPro: Precorrin-8X methylmutase CbiC/CobH TIGRFAM: redox_disulf_1: redox-active disulfide; High confidence in function and specificity. | Cob(I)yrinic acid a,c-diamide adenosyltransferase; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids. | 0.534 |
cbiC | cobQ | azo3531 | azo3517 | Precorrin-8X methylmutase. CATALYZES THE CONVERSION OF PRECORRIN-8X TO HYDROGENOBYRINIC ACID; A Cobalamin biosynthesis precorrin isomerase. METHYL MIGRATION REACTION DURING THE TRANSFORMATION OF PRECORRIN-3 TO FORM COBYRINIC ACID (BY SIMILARITY). InterPro: Precorrin-8X methylmutase CbiC/CobH TIGRFAM: redox_disulf_1: redox-active disulfide; High confidence in function and specificity. | Cobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. | 0.983 |
cbiC | cobU | azo3531 | azo3557 | Precorrin-8X methylmutase. CATALYZES THE CONVERSION OF PRECORRIN-8X TO HYDROGENOBYRINIC ACID; A Cobalamin biosynthesis precorrin isomerase. METHYL MIGRATION REACTION DURING THE TRANSFORMATION OF PRECORRIN-3 TO FORM COBYRINIC ACID (BY SIMILARITY). InterPro: Precorrin-8X methylmutase CbiC/CobH TIGRFAM: redox_disulf_1: redox-active disulfide; High confidence in function and specificity. | Cobinamide kinase/cobinamide phosphate guanylyltransferase; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate. | 0.551 |