STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
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[Homology]
Score
azo3524Conserved hypothetical nitroreductase. Homology to cv1555 of C. violaceum of 72% (trembl|Q7NXS1). Involved in the reduction of nitrogen containing compounds. InterPro: Nitroreductase family (IPR000415). Pfam: Nitroreductase family. no signal peptide. no TMHs; Conserved hypothetical protein. (218 aa)    
Predicted Functional Partners:
cobT
Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).
 
 0.993
cobB
Cobyrinic acid AC-diamide synthase. Responsible for the amidation of carboxylic groups at position A and C of either cobyrinic acid or hydrogenobrynic acid. NH(2) groups are provided by glutamine and one molecule of ATP is hydrogenolyzed for each amidation (By similarity). cbiA: cobyrinic acid ac-diamide synthase; High confidence in function and specificity.
  
 0.941
cobU
Cobinamide kinase/cobinamide phosphate guanylyltransferase; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.
 
 0.889
ubiX
3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family.
     
  0.855
nmoB
Nitrilotriacetate monooxygenase component B (EC 1.14.13.-) (NTA monooxygenase component B) (NTA-MO B). HYDROXYLATION OF NITRILOTRIACETATE. TREMBL:Q93NA5:48% identity, 62% similarity InterPro: IPR002563; Flavin_Reduct. IPR009002; FMN_binding. Pfam:PF01613; Flavin_Reduct Non-secretory protein with low signal peptide probability (0.002) Absence of transmembrane helices; High confidence in function and specificity.
  
 
 0.840
azo1962
Conserved hypothetical flavin reductase. Homology to rsc0763 of R. solanacearum of 43% (TREMBL:Q8Y1C7). Pfam: Flavin reductase like domain. This is a flavin reductase family consisting of enzymes known to be flavin reductases as well as various oxidoreductase and monooxygenase components. no signal peptide. no TMHs; Conserved hypothetical protein.
  
 
 0.840
ntaB
Nitrilotriacetate monooxygenase component B (EC 1.14.13.-) (NTA monooxygenase component B) (NTA-MO B). HYDROXYLATION OF NITRILOTRIACETATE. TREMBL:Q7W4Q0: 46% identity, 65% similarity InterPro: Flavin reductase-like domain Interpro:IPR002563 Pfam:PF01613 No signal peptide No transmembrane helices monomer_idh: isocitrate dehydrogenase NA; High confidence in function and specificity.
  
 
 0.840
cobC
Cobalamin biosynthesis protein, CobC. CobC is probable involved in the conversion of cobyric acid to cobinamide.Similar to pir|B83486 (48%) and to sprot|COBC_PSEDE (42%). InterPro (PF00155): Aminotransferases class-I and II; Specificity unclear.
 
  
 0.837
cobA2
Uroporphyrin-III C-methyltransferase (Urogen III methylase) (SUMT) (Uroporphyrinogen III methylase) (UROM). TIGRFAM: dph5: diphthine synthase; High confidence in function and specificity; Belongs to the precorrin methyltransferase family.
  
 
 0.826
azo0039
Conservd hypothetical protein, 79% identity(85% similarity) to TrEMBL;Q88GU7. Has PF02566, OsmC-like protein; IPR003718; Osmotically inducible protein C (OsmC) (P23929) is a stress -induced protein found in E. Coli. This family also contains a organic hydroperoxide detoxification protein (O68390) that has a novel pattern of oxidative stress regulation. Has PF02624, YcaO-like fatty acid binding protein;IPR003776, DUF181;This is a family of proteins of unknown function.
  
  
 0.791
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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