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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
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a 3D structure is known or predicted
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[Homology]
Score
azo3528Conserved hypothetical membrane protein. Homology to blr3274 of B. japonicum of 33% (gnl|keqq|bja:blr3274(KEGG)). Pfam: weak hit to CbiM, an integral membrane protein involved in cobalamin synthesis. TMHMM reporting 5 transmembrane helices. No signal peptide; Conserved hypothetical protein. (208 aa)    
Predicted Functional Partners:
cbiC
Precorrin-8X methylmutase. CATALYZES THE CONVERSION OF PRECORRIN-8X TO HYDROGENOBYRINIC ACID; A Cobalamin biosynthesis precorrin isomerase. METHYL MIGRATION REACTION DURING THE TRANSFORMATION OF PRECORRIN-3 TO FORM COBYRINIC ACID (BY SIMILARITY). InterPro: Precorrin-8X methylmutase CbiC/CobH TIGRFAM: redox_disulf_1: redox-active disulfide; High confidence in function and specificity.
 
 
 0.939
cbiE
Precorrin-6Y C(5,15)-methyltransferase (decarboxylating); Precorrin-6 methyltransferase (Precorrin-6Y methylase). CATALYZES THE METHYLATION OF BOTH C-5 AND C-15 IN PRECORRIN-6Y TO FORM PRECORRIN-8X. InterPro: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; High confidence in function and specificity.
 
 
 0.932
cbiD
CbiD protein; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.
 
 
 0.915
cbiQ
Putative cobalt transport system permease protein; Part of the ABC transporter complex cbiKMQO involved in cobalt import. Similar to the cobalt transport membrane protein, CbiQ in A. pleuropneumoniae; Function unclear.
 
 
 0.908
azo1044
Conserved hypothetical membrane protein. Homology to ebA4769 of Azoarcus sp. EbN1 of 53% (gnl|keqq|eba:ebA4769(KEGG)). Pfam: Cobalt transport protein. signal peptide. 3 TMHs; Family membership.
  
 
 0.896
azo3529
Probable Precorrin-4 C11-methyltransferase,47% Identity to TrEMBL;Q8GDX1, O26702. SwissProt;O87696. Has PF00590, Tetrapyrrole (Corrin/Porphyrin) Methylases;IPR000878 Cor/por_Metransf; This family uses S-AdoMet in the methylation of diverse substrates. This family includes a related group of bacterial proteins of unknown function, including P45528. This family includes the methylase Dipthine synthase. Uroporphyrin-III C-methyltransferase (EC: 2.1.1.107) (SUMT)catalyzes the transfer of two methyl groups from S-adenosyl-L-methionine to the C-2 and C-7 atoms of uroporphyrinogen III to yiel [...]
  
  
 0.894
cbiL
Precorrin-2 C20-methyltransferase (EC 2.1.1.130) (S-adenosyl-L- methionine:precorrin-2 methyltransferase) (SP2MT). METHYLATES PRECORRIN-2 AT THE C-20 POSITION TO PRODUCE PRECORRIN-3A; High confidence in function and specificity.
 
  
 0.890
cbiX
CbiX conserved hypothetical protein. Function unknown. Cobalamin biosynthesis pathway; Function unclear.
 
  
 0.841
cbiO
Putative cobalt transport system ATP-binding protein; Part of the ABC transporter complex cbiKMQO involved in cobalt import. Probably responsible for the translocation of the substrate across the membrane. 40% AAA_ATPase.IPR003439; ABC_transporter. Pfam:PF00005; ABC_tran; 1. ProDom; PD000006; ABC_transporter; 1. SMART; SM00382; AAA; 1; High confidence in function and specificity.
  
 
 0.828
azo2910
ATP-binding cassette (ABC) transporters form a large family of proteins responsible for translocation of a variety of compounds across biological membranes. They are composed of two transmembrane domains responsible for binding and transport and two nucleotide-binding domains responsible for coupling the energy of ATP hydrolysis to conformational changes in the TMDs, TREMBL:Q8FZX0 (58% identity); TREMBL:Q8U6Y9 (59% identity). InterPro (IPR003593): AAA ATPase. InterPro (IPR001687): ATP/GTP-binding site motif A (P-loop). InterPro (IPR003439): ABC transporter. Pfam (PF00005): ABC transpor [...]
     
  0.816
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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