Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
azo3540Conserved hypothetical transcriptional regulatory protein. Homology to rsc0599 of R. solanacearum of 63% (trembl|Q8Y1U0). InterPro: Bacterial regulatory proteins GntR family (IPR000524). Pfam: Bacterial regulatory protein, gntR family; Aminotransferase classI and II. no signal peptide. no TMHs; Conserved hypothetical protein. (504 aa)    
Predicted Functional Partners:
gltB
Ferredoxin-dependent glutamate synthase,; Specificity unclear.
     
  0.880
gcvP
Glycine cleavage system P-protein; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.
   
 
 0.698
pheA
Bifunctional chorismate mutase/prephenate dehydratase P-protein, pheA,; High confidence in function and specificity.
    
 0.669
azo0480
Conserved hypothetical irons-sulfur binding oxidase. Homology to cv4235 of C. violaceum of 70% (trembl|Q7NQA5) Pfam: FAD binding domain; FAD linked oxidase, Cterminal domain Tigrfam: glcD: glycolate oxidase subunit GlcD no signal peptide no TMHs; Family membership.
 
  
  0.598
lpdA
Dihydrolipoamide dehydrogenase. Homology to lpdA of N. meningitides of 70% (trembl|Q59099). THE BRANCHED-CHAIN ALPHA-KETO DEHYDROGENASE COMPLEX CATALYZES THE OVERALL CONVERSION OF ALPHA-KETO ACIDS TO ACYL-COA AND CO(2). IT CONTAINS MULTIPLE COPIES OF 3 ENZYMATIC COMPONENTS: BRANCHED-CHAIN ALPHA-KETO ACID DECARBOXYLASE (E1) LIPOAMIDE ACYLTRANSFERASE (E2) AND LIPOAMIDE DEHYDROGENASE (E3) (BY SIMILARITY). InterPro: FAD-dependent pyridine nucleotide-disulphide oxidoreductase (IPR001327); Pyridine nucleotide-disulphide oxidoreductase, classI (IPR001100); biotin/Lipoyl attachment (IPR000089) [...]
     
  0.556
azo1166
Conserved hypothetical iron-sulfur binding oxidase. Homology to pa4772 of P. aeruginosa of 53% (pir|H83050) InterPro: FAD linked oxidase C-terminal (IPR004413) Pfam: FAD binding domain; Fad linked oxidase, C-terminal domain Tigrfam: glcD: glycolate oxidase subunit GlcD no signal peptide no TMHs; Family membership.
    
  0.536
azo3539
Hypothetical secreted protein. no homology of the entire protein to the data bank. no domains predicted. signal peptide. no TMHs.
       0.504
boxA
Benzoyl-CoA oxygenase component A. 84% 4Fe4S_ferredoxin. IPR001709; FPN_cyt_redctse. IPR001433; Oxred_FAD/NAD(P). Pfam:PF00037; Fer4; 2. PF00175; NAD_binding_1; 1; High confidence in function and specificity.
    
   0.490
azo3336
Conserved hypothetical protein,ybgI, 48% identity(67% similarity) to SwissProt;P75743(E.coli)SP|Q8XFW7. SwissProt;Q8XVA0(58% identity)Ralstonia solanacearum. TrEMBL;Q82UH6(53% identity)Nitrosomonas europaea. Has PF01784, NIF3 (NGG1p interacting factor 3);IPR002678, DUF34; This family contains several NIF3 (NGG1p interacting factor 3) protein homologues. NIF3 interacts with the yeast transcriptional coactivator NGG1p which is part of the ADA complex, the exact function of this interaction is unknown.
   
    0.487
azo3485
Conserved hypothetical iron-sulfur binding protein. Homology to pb1470 of B. pertussis of 48% (trembl|Q7VY84). Transfer of electrons in a wide variety of metabolic reactions. InterPro: 4Fe-4S ferredoxin iron-sulfur binding domain (IPR001450). Pfam: 4Fe-4S binding domain. no signal peptide. no TMHs; Family membership.
    
   0.447
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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