Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
azo3542Conserved hypothetical glutathione transferase. Homology to psto0703 of P. syringae of 74% (trembl|Q889P6). Bacterial GSTs of known function often have a specific, growth-supporting role in biodegradative metabolism Pfam. Glutathione S-transferase, N-terminal; Glutathione S-transferase, C-terminal. no signal peptide. no TMHs; Family membership. (291 aa)    
Predicted Functional Partners:
lysS
Lysyl-tRNA synthetase (EC 6.1.1.6) (Lysine--tRNA ligase) (LysRS); High confidence in function and specificity; Belongs to the class-II aminoacyl-tRNA synthetase family.
   
  0.802
azo2485
Conserved hypothetical protein. Homology to eca2717 of E. carotovora of 35% (tremble:Q6D3M7). no domains predicted. no signal peptide. no TMHs.
   
  0.802
leuS
Leucine--tRNA ligase; Unnamed protein product; Region start changed from 3544790 to 3544922 (-132 bases); Belongs to the class-I aminoacyl-tRNA synthetase family.
   
 0.779
azo3541
Hypothetical methyltransferase. no Homology of the entire protein with the data bank. Pfam: Putative methyltransferase This is a family of hypothetical proteins which are putative methyltransferases. The aligned region contains the GXGXG S-AdoMet binding site suggesting a putative methyltransferase activity. Interpro: SAM (and some other nucleotide) binding motif(IPR000051) no signal peptide no TMHs.
       0.773
proS
Proline--tRNA ligase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacy [...]
   
  0.772
metG
MetG protein; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
    
 0.756
argS
Putative arginine-tRNA ligase (EC 6.1.1.19). Homology to argS of E. coli of 25% (sprot:SYR_ECOLI) CATALYTIC ACTIVITY: ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg). InterPro: Arginyl-tRNA synthetase (IPR001278); Aminoacyl-transfer RNA synthetase class-I (IPR001412) Tigrfam: argS: arginyl-tRNA synthetase Pfam: tRNA synthetases class I no signal peptide no TMHs; Family membership.
   
  0.749
ileS
IleS protein; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
   
 0.725
rplR
50S ribosomal protein L18; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
   
  0.713
gluQ
Glutamate-tRNA ligase; Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2- cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon; Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily.
   
  0.710
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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