STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
azo3554Putative ABC transporter system, permease protein; Region start changed from 3899167 to 3899122 (-45 bases); Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily. (326 aa)    
Predicted Functional Partners:
azo3553
Putative ABC-type transporter, ATPase component; 37% Similar to the iron(III)-hydroxamate transport membrane protein, fhuC in E.coli.Part of the ABC transporter complex fhuACDB involved in iron(III)-hydroxamate import. Probably responsible for energy coupling to the transport system. SWISSPROT:FHUC_ECOLI:P07821 InterPro:IPR003593; AAA_ATPase.IPR003439; ABC_transporter. Pfam:PF00005; ABC_tran; 1; High confidence in function and specificity.
 
 0.999
btuF
Vitamin B12 transport protein btuF precursor. 34% Similar to BtuF from E.coli. Part of the binding-protein-dependent transport system for vitamin B12. Acts with btuCD to transport vitamin B12 across the inner membrane. SWISSPROT:BTUF_ECOLI:P37028 InterPro:IPR002491; Peripla_BP. Pfam: PF01497; Peripla_BP_2; 1. Signal peptide: present. Contains 1 iron siderophore/cobalamin periplasmic-binding domain; High confidence in function and specificity.
 
 0.996
azo0387
Conserved hypothetical periplasmic binding proten. Homology to rs03250 of R. solanacearum of 53% (trembl|Q8Y2Q2). Interpro: Periplasmic binding protein (IPR002491). Pfam: Periplasmic binding protein (PF01497). This family includes bacterial periplasmic binding proteins. Several of which are involved in iron transport. no signal peptide. no TMHs; Conserved hypothetical protein.
 
 0.987
cobA2
Uroporphyrin-III C-methyltransferase (Urogen III methylase) (SUMT) (Uroporphyrinogen III methylase) (UROM). TIGRFAM: dph5: diphthine synthase; High confidence in function and specificity; Belongs to the precorrin methyltransferase family.
     
 0.833
cobO
Cob(I)yrinic acid a,c-diamide adenosyltransferase; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids.
     
 0.775
cobB
Cobyrinic acid AC-diamide synthase. Responsible for the amidation of carboxylic groups at position A and C of either cobyrinic acid or hydrogenobrynic acid. NH(2) groups are provided by glutamine and one molecule of ATP is hydrogenolyzed for each amidation (By similarity). cbiA: cobyrinic acid ac-diamide synthase; High confidence in function and specificity.
     
 0.767
azo3555
TonB-dependent receptor, putative; COBALAMIN RECEPTOR PROTEIN; Specificity unclear.
 
     0.752
azo3556
Putative outer membrane TonB-dependent receptor,probably involved in iron metabolism. 20% Similar to the IrgA enterobactine outer membrane receptor in V. cholerae. INVOLVED IN THE INITIAL STEP OF IRON UPTAKE BY BINDING FERRIC VIBRIOBACTIN AN IRON CHELATIN SIDEROPHORE THAT ALLOWS V.CHOLERAE TO EXTRACT IRON FROM THE ENVIRONMENT. SWISSPROT:IRGA_VIBCH:P27772. 21% TonB_boxC. Pfam:PF00593; TonB_dep_Rec; 1; Specificity unclear.
 
     0.568
azo1830
Putative TonB-denpendent receptor; Similar to FepA, an iron regulated outer membrane protein. FepA is a receptor for the siderophore complex ferric enterobactin and for colcins B and D. INVOLVED IN THE INITIAL STEP OF IRON UPTAKE BY BINDING FERRIC ENTEROBACTIN THAT ALLOWS E. COLI TO EXTRACT IRON FROM THE ENVIRONMENT. ilvC: ketol-acid reductoisomerase; Function unclear.
 
  
 0.548
azo2156
TonB-dependent outer membrane receptor involved in the first step of iron internalization and metabolism. A short conserved region so called the tonB-box is present in the sequence. This domain is involved in the interaction of the receptor with the TonB protein. Similar to a E. coli iron(III) dicitrate transport protein fecA precursor. InterPro: TonB-dependent receptor protein arcC: carbamate kinase; Function unclear.
 
  
 0.515
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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